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diet-induced obesity

Mice lacking ghrelin receptors resist 
the development of diet induced obesity

Mice lacking ghrelin receptors resist the development of diet induced obesity

... mice to a challenge with a Western-type, calorie-dense diet. Indeed, our results suggest that ghrelin signaling is required for the full development of diet-induced obesity. In particular, ...

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Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet- induced obesity model

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet- induced obesity model

... fat diet (LFD, 3% Kcal fat) or diet-induced obesity treatment (DIO) with medium fat diet (MFD 14% Kcal fat), fructose in water (5%), and a single intraperitoneally ...

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Paradoxical resistance to diet induced obesity in UCP1 deficient mice

Paradoxical resistance to diet induced obesity in UCP1 deficient mice

... to obesity in the human popu- ...to obesity occur even when the levels of food intake and physical activity are similar, individual differences in metabol- ic efficiency and thermogenesis probably are ...

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 ANTI-OBESITY PROPERTY OF HEXANE EXTRACT FROM THE LEAVES OF GYMNEMA SYLVESTRE IN HIGH FED CAFETERIA DIET INDUCED OBESITY RATS

 ANTI-OBESITY PROPERTY OF HEXANE EXTRACT FROM THE LEAVES OF GYMNEMA SYLVESTRE IN HIGH FED CAFETERIA DIET INDUCED OBESITY RATS

... cafeteria diet induced obesity in Sprague dawley ...basal diet without any treatment, Group-II (obesity control) were induced obesity and only on basal diet without ...

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Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

... Results: Our parabiosis and bone marrow transplantation experiments revealed a significant infiltration of circulating LysM GFP cells into the liver, skeletal muscle, choroid plexus, and leptomeninges but not in the ...

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Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

... increased diet-induced hypothalamic inflammation Because LIF expression was rapidly induced in the hypothal- amus of OR mice fed a HFD, we hypothesized that it could play a protective role against ...

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Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis

Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis

... Three hundred and thirty-two high-fat diet responsive genes were used for core network analysis identified previously (Do et al. 2011). General study flow for the network analysis is illustrated in Fig. 1. To ...

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Diet-induced obesity in rats leads to a decrease in sperm motility

Diet-induced obesity in rats leads to a decrease in sperm motility

... Background: Obesity is rapidly becoming a worldwide epidemic that affects children and ...between obesity and infertility, but until now it remains ...high-fat diet-induced obesity on ...

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INFLUENCE OF ALPINIA GALANGA RHIZOMES ON CAFETERIA DIET 
INDUCED OBESITY IN RATS

INFLUENCE OF ALPINIA GALANGA RHIZOMES ON CAFETERIA DIET INDUCED OBESITY IN RATS

... cafeteria diet fed obese rats. Obesity was induced in albino rats by feeding cafeteria diet daily for 6 weeks in addition to normal ...weight induced by cafeteria diet, without ...

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Thrombin promotes diet induced obesity through fibrin driven inflammation

Thrombin promotes diet induced obesity through fibrin driven inflammation

... to diet-induced obesity, fibrin(ogen) immunohistochemis- try was performed on epididymal white adipose tissue and liver sections from WT mice fed either a control diet (CD) or a high-fat ...

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Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

... treat obesity [13,23], it remains unclear whether zebrafish can be used as a model for diet-induced obesity (DIO), similar to that observed in ...

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Clostridium ramosum Promotes High Fat Diet Induced Obesity in Gnotobiotic Mouse Models

Clostridium ramosum Promotes High Fat Diet Induced Obesity in Gnotobiotic Mouse Models

... in obesity development in gnotobiotic ...high-fat diet (HFD) or a low-fat diet ...of obesity and metabolic diseases were ...intake, diet digestibility, gut permeability, and parameters ...

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Mice lacking the syndecan 3 gene are resistant to diet induced obesity

Mice lacking the syndecan 3 gene are resistant to diet induced obesity

... of obesity that also clearly depends on gene-envi- ronment interactions (8, ...HF dietinduced obesity due to both reduced caloric intake and increased energy expenditure; in contrast, female ...

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Diet-induced obesity increases NF-κB signaling in reporter mice

Diet-induced obesity increases NF-κB signaling in reporter mice

... We observed increased NF-jB activity in the thoracic region of HFD-fed female mice, indicative of increased activity in the thymus and/or thoracic lymph nodes (i.e. axillary, brachial lymph nodes). To what extent HFD may ...

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Anti-obesity and antioxidant effects of Probucol against high fat diet-induced obesity in rats

Anti-obesity and antioxidant effects of Probucol against high fat diet-induced obesity in rats

... into obesity and diabetes [50]. In the present study, high-fat diet was administered to 8-week-old to induce severe obesity and diabetes and the effects of probucol were ...High-fat diet is ...

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Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity

Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity

... of obesity among indi- vidual animals was addressed by the experimental and control cohorts containing animals individually match-paired by pretreatment body mass and body composition ...

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Effect of Phoenix deactylifera on high fat diet induced obesity

Effect of Phoenix deactylifera on high fat diet induced obesity

... Body weight increased significantly in rats fed on HFD compared with controls (fed on normal diet) (Table 2). Treatment with Phoenix dactylifera reduced body weight of HFD fed obese rats. Similar reports of ...

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IL-33, diet-induced obesity, and pulmonary responses to ozone

IL-33, diet-induced obesity, and pulmonary responses to ozone

... 16S rRNA gene sequencing of fecal DNA was performed to evaluate differences in the gut microbial community structures induced by ST2 deficiency, cohousing, and HFD feeding. Sequencing was performed at the ...

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Ablation of TRIP-Br2, a novel regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

Ablation of TRIP-Br2, a novel regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

... with HFD (n=6 per group). (b) Left, rectal temperature measured for WT or KO mice fed chow diet at room temperature (n=9 per group). Right, rectal temperature measured for WT or KO mice on chow diet housed ...

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The Role of AEBP1 in Sex-Specific Diet-Induced Obesity

The Role of AEBP1 in Sex-Specific Diet-Induced Obesity

... that obesity is associated with accumulation in adipose tissue of macrophages, which par- ticipate in inflammatory pathways that are activated in adipose tissues of obese individuals ...

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