Differential sensitivity
Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signalling
... Hedgehog (Hh) signalling has been implicated in the development of osteoblasts and osteoclasts whose balanced activities are critical for proper bone formation. As many mouse mutants in the Hh pathway are embryonic ...
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Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032
... of Raf, as has been described for cell lines with acquired resistance to a different Raf-inhibitor, AZ628, which show increased signaling through C-Raf [23]. The increase in pErk in an NRAS Q61L mutant cell line could be ...
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Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation
... Our findings are consistent with the notion that resis- tance against depotentiation requires protein synthesis [9]. In other words, LTP2 is more resistant to depotentiation because of the nature of the potentiation ...
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Differential Sensitivity of Bacillus Sp. Isolated from Archive Materials to Plant Extracts
... Previous research has shown that the antimicrobial activity of plant extracts is due to different secondary metabolites present in the plants, including: essential oils, triterpenoids,[r] ...
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Genetic signature of differential sensitivity to stevioside in the Italian population
... We found evidence that TAS2R14 rs3741843 (A/G) has a significant impact on bitterness perception. Through com- paring the ‘‘bitter-low’’ and ‘‘bitter-high’’ groups, the allelic frequency of this SNP was found to be ...
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Differential sensitivity of normal and transformed human cells to reovirus infection.
... Because observation of infected cells indicated that trans- infection of L cells results in an inhibition of forned WI-38 cells were more sensitive to reo- cullular DNA synthesis which o[r] ...
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DIFFERENTIAL SENSITIVITY OF MOUSE SPERMATOGENESIS TO ALKYLATING AGENTS
... Chromosome breaks estimated by anaphase fragments are plotted in Figure 1 A, which shows that (1) the sensitivity of various stages is different for the three compounds; and [r] ...
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DIFFERENTIAL SENSITIVITY OF NH4+ AND NO2? OXIDATION TO CdCl2 AND AlCl3 IN AN AQUEOUS SYSTEM
... has been reported by several investigators [3,7]. Olson [10] and Ward et al. [16] have reported the differential photoinhibition of the two steps of the nitrification process and later Diab and Shilo [3] showed ...
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Differential Sensitivity of Murine Leukemia Virus to APOBEC3-Mediated Inhibition Is Governed by Virion Exclusion
... code an APOBEC3 protein that is active in restricting HIV-1 infectivity (16), even though no rodent lentiviruses are known, suggests that the APOBEC3 proteins may have originally evolved to prevent the replication of ...
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FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism.
... retained sensitivity to HSP90 inhibitor treatment by the ansamycins 17-AAG and 17-DMAG yet displayed intrinsic resistance to ganetespib or AUY922, both second-generation resorcinol-based ...
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Wheat starch biosynthesis : organ specific expression of genes encoding ADP glucose pyrophosphorylase
... In view of the differential sensitivity of wheat leaf and wheat endosperm ADP-glucose pyrophosphorylase enzymes to activation by 3-phosphoglycerate and inhibition by orthophosphate Fente[r] ...
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Leukotriene receptors as potential therapeutic targets
... Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction in vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.. Am[r] ...
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Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation.
... T h e separation of functions in these alleles does not reflect differential sensitivity of all cells with impaired Cbflp function to one of the growth media since both an[r] ...
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Effect of interleukin 1β on spinal cord nociceptive transmission of normal and monoarthritic rats after disruption of glial function
... a differential sensitivity of normal and monoarthritic rats to IL-1β administra- tion into the spinal cord, suggesting that adjuvant-induced arthritis in rat did not result in marked upregulation of glial ...
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BASE-CHANGE MUTAGENESIS AND PROPHAGE INDUCTION IN STRAINS OF ESCHERICHIA COLI WITH DIFFERENT DNA REPAIR CAPACITIES
... Since the differential sensitivity to mutation between wild type (denoting the wild-type DNA repair capacity) and Exc- paralleled that to killing, we conclude that the same exc[r] ...
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Enhanced Sensitivity of the Postnatal Lung to Environmental Insults and Oxidant Stress
... of differential sensitivity and differential response of the “differentiating” respiratory epithelium can be seen in studies comparing the initiation of inflamma- tion after endotoxin exposure in ...
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Polymorphism, mesomorphism, and metastability of monoelaidin in excess water
... ABSTRACT The polymorphic and metastable phase behavior of monoelaidin dry and in excess water was studied by using high-sensitivity differential scanning calorimetry and time-resolved x-[r] ...
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Sensitivity analysis for parametric vector optimization problems using differential equations approach
... obtaining sensitivity information for parametric vector opti- mization problems (VOP) v is presented, where the parameters in the objective functions and anywhere in the ...
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Theoretical foundations for traditional and generalized sensitivity functions for nonlinear delay differential equations
... theoretical sensitivity results for the DDE example for HIV dynamics with measure dependent or distributional parameters given in [10]; however they only present results for the the sensitivity with respect ...
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Electrochemical Behavior of Ambroxol and Its Determination in Pharmaceutical Dosage Forms on MWCNT/Nafion Modified Glassy Carbon Electrodes
... by differential pulse ...anodic differential pulse voltammetric scan was made and the peak current was ...measured. Differential pulse voltammetry was employed for the measurement of ABX under the ...
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