Differentially Methylated Regions between A12Dhd and
De novo identification of differentially methylated regions in the human genome
... Initial output consists of a data frame describing each region, ranked by its corresponding P value. Useful infor- mation such as genomic coordinates, gene associations and number of constituent CpGs per region are also ...
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De novo identification of differentially methylated regions in the human genome
... Initial output consists of a data frame describing each region, ranked by its corresponding P value. Useful infor- mation such as genomic coordinates, gene associations and number of constituent CpGs per region are also ...
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Detection of differentially methylated regions of irradiated fig tree selections
... polymorphic regions, analyzable by bioin- formatic ...the differentially methylated sites, makes it possible to observe different patterns of methylation by sequencing the treated DNA with sodium ...
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Prediction of gestational age based on genome wide differentially methylated regions
... Tables S5. Practical implications The prediction model described here is based on DNA extracted from cord blood from newborns. Our GA predictor establishes a more assured link between GA and methylation, which may ...
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BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions
... standard regions as ...capture regions. For the first definition of positive and negative regions, we include regions for which at least two out of three can- cer samples and at least two out ...
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Comprehensive methylation analysis of imprinting-associated differentially methylated regions in colorectal cancer
... association between HyMiD-positive status and the above two CIMP ...correlation between CIMP-positive status and KRAS mutations was an unanticipated result, but consistent with previous re- ports ...
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Inter-individual methylation variability in differentially methylated regions between maternal whole blood and first trimester CVS
... differences between fetal and maternal DNA, several groups have managed to identify biomarkers using different ...specific methylated re- gions using the MeDIP-qPCR ...selected regions had distinct ...
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methylCC: technology independent estimation of cell type composition using differentially methylated regions
... either methylated or unmethylated for each purified cell type, our model can account for the platform-specific biases directly and model methylation states using latent ...in regions independent of ...
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Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths
... correlation between DNA methylation in the brain and blood, as shown in a previous analysis [29], highlighting the possible biological relevance of our find- ings on the emergence of ...
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Major chromosomal breakpoint intervals in breast cancer co-localize with differentially methylated regions
... breakpoint regions with differentially methylated regions (DMR), coupled with additional genomic parameters, such as repeat elements and designated “fragile sites” in the reference ...
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Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
... promoter regions and CpG islands, and also covers other potentially relevant features, including downstream genic and intergenic ...tDMRs between the ...in regions outside CGIs or CGI flanking ...
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Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions
... Results: Using whole genome bisulphite sequencing of DNA from the livers of five mice from the A vy colony, we searched for sites at which DNA methylation differed among the mice. A small number of loci, 356, were ...
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Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
... with differentially methylated regions (DMRs) whereby one of the two alleles is DNA methylated depending on the parent of ...regulatory regions associated with a particular gene, only ...
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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
... Discussion We identify hundreds of CpG-sites that exhibit age-related directional changes in methylation. The majority of these effects are hyper-methylated with age, a large proportion replicate in an independent ...
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Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer
... A between-array normalization was applied to the type Ι and type ΙΙ probes separately using the DASEN method within the wateRmelon Bioconductor R package ...the methylated probe intensity and the overall ...
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DMRcaller: a versatile R/Bioconductor package for detection and visualization of differentially methylated regions in CpG and non-CpG contexts
... in tilling bins and pooling together the methylation levels of all cytosines in each bin. Here, we present a new R package DMRcaller, which can compute DMRs between two samples in a methylation con- text dependent ...
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Epigenetic signature of differentially methylated genes in cutaneous melanoma
... Abstract Background: Cutaneous melanoma (CM) is the most aggressive subtype of skin cancer, with increasing incidence over the past several decades. DNA methylation is a key element of several biological processes such ...
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Identification of aberrantly methylated differentially expressed genes targeted by differentially expressed miRNA in osteosarcoma
... correlation between PYCARD hypermethylation and down-regulation in OS, and verified that its low expression levels indicated worse prognosis based on clinical ...
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CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer’s disease
... entially methylated in the hippocampus of AD pa- ...promoter regions of CRTC1 in hippocampal samples from a cohort of neuropathologically defined “pure” AD cases and ...relationship between DNA ...
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Identification of differentially methylated genes in the malignant transformation of ovarian endometriosis
... relationship between methyla- tion of the nine candidate genes and EAOC, but lim- ited by the amount of target tissue obtained from FFPE tissue, especially the ectopic endometrial tissues, we could choose only one ...
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