disability progression
Relating relapse and T2 lesion changes to disability progression in multiple sclerosis: a systematic literature review and regression analysis
... EDSS progression across a wide range of RCTs for RRMS ...and disability progression in other forms of ...of disability progression than new and enlarging T2 ...EDSS progression ...
14
Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study
... disease progression fell short of statistical significance and showed high heterogeneity (Handel et ...disease progression in multiple sclerosis is of particular interest in view of reports on a negative ...
7
The effect of disease modifying therapies on disability progression in multiple sclerosis: A systematic overview of meta analyses
... sustained disability progression) in their ...of disability progression also varied between meta-analyses and, at times, between studies included in the ...
25
Evolution of Cortical and Thalamus Atrophy and Disability Progression in Early Relapsing Remitting MS during 5 Years
... Subjects. In total, 180 patients with RRMS (90 patients each in the SDP and stable disease groups, according to the 5-year classification) were included in the study. The disability progression status was ...
9
Long-term disability progression of pediatric-onset multiple sclerosis
... years) had no measurable effect on the longer-term trajectory of disease, though only 15 persons were in this category, therefore the analysis may have been underpowered to detect a difference. While the vast majority had ...
11
A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression
... In MS, T2W-lesions are attributable to a variety of pathological reactions, including inflammatory demye- lination, gliosis, edema, and axonal swelling and loss [22, 23], whereas brain volume loss reflects neuro-axonal ...
11
Smoking cessation and the reduction of disability progression in Multiple Sclerosis: a cohort study
... on progression is independent of disease duration, age at onset, sex, initial type of MS, and DMTs ...each disability landmark were not associated with the risk of reaching EDSS ...
26
Health Assessment Questionnaire disability progression in early rheumatoid arthritis: Systematic review and analysis of two inception cohorts
... functional disability over time and (ii) to identify common trajectories of HAQ progression over 15 years in two large prospective observational studies from the UK, ...
14
Brain Atrophy Is Associated with Disability Progression in Patients with MS followed in a Clinical Routine
... The present study is one of the first large cohort studies of brain atrophy measurement in patients with MS and CIS followed in a clinical routine. The study showed that T2-FLAIR– derived LVV measurement was the most ...
6
Effects of disease modifying therapies on brain and grey matter atrophy in relapsing remitting multiple sclerosis
... An exploratory analysis on the cladribine tablets treating multiple sclerosis orally (CLARITY) study (phase-3, double-blind, placebo-controlled, multicenter trial in patients with RMS assessing the effects of cladribine ...
10
Update on immunopathogenesis and immunotherapy in multiple sclerosis
... reduced disability progression and relapse rates (reduction of relapse rate by 63% during the first year and 68% during the second year of treatment compared with placebo) in highly active relapsing- ...
10
The short and long-term effects of pregnancy on multiple sclerosis and experimental autoimmune encephalomyelitis
... Portaccio, E., et al., Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs. Vukusic, S., et al., Pregnancy and m[r] ...
27
Scaling the mountain: The topography of disability and transition to Higher Education in the Republic of Ireland
... education” (National Council for Curriculum and Assessment /HEA, 2010) provides post-primary students with an opportunity to learn about strengths, interests and abilities, and post-secondary educational opportunities. ...
466
What is the impact of socioeconomic status on multiple sclerosis?About multiple sclerosis
... To see if socioeconomic status (SES) affected MS-related disability, the authors reviewed 2 databases containing information on patients with MS. One was from British Columbia, Canada, and the other from Cardiff, ...
5
Sports Injuries to High School Athletes With Disabilities
... study, we did not observe any seizure-induced injuries. However, athletes with histories of seizures were at increased risk for all other sports-related injury, not necessarily seizure-induced injuries. On one hand, this ...
9
Incidence, prevalence, and hybrid approaches to calculating disability-adjusted life years
... The second apparent solution to our original puzzle is to take the opposite route and to change the method for calculating YLLs to bring it in line with that used when calculate YLDs [10]. Rather than looking at events ...
7
Understanding Disability: Biopsychology, Biopolitics, and an In-Between-All Politics
... commonality. APA is a field that, as the editors of this volume in their personal correspondence reminded me, that focuses on the moving body. But what do we do to this body and what are the potential consequences? APA ...
25
Evaluating the External Validity of High-Incidence Special Education Disability Categories.
... Despite their advantages, many researchers warn of the unintended yet harmful consequences associated with categorizingstudents with disabilities (Triano, 2000). As an example, Hollenweger (2008) notes that the stigma of ...
144
Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson’s disease: the LEAP-study
... First, we discuss the stratification for type of hospital, age and disease duration. We stratified by type of hos- pital (university medical centre versus non-university medical centre) because of possible differing ...
8
Atrophy in multiple sclerosis: Measurement and clinical implications
... breakdown. Thirdly the relationship of enhancement over 10 months to the development of atrophy over 12 and 18 months was examined. It is possible that this is misleading and that the development of atrophy may be a ...
147