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disease associations

Benchmark of computational methods for predicting microRNA disease associations

Benchmark of computational methods for predicting microRNA disease associations

... miRNA-disease associations for less-studied diseases ...prioritized disease causal miRNAs; therefore, the pre- diction scores cannot be considered as a primary reference for screening target miRNAs ...

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Predicting metabolite-disease associations based on KATZ model

Predicting metabolite-disease associations based on KATZ model

... the associations between metabolites and diseases is only a tip of the iceberg, which indicates that thousands of potential metabolism and disease associations need to be tested and ...potential ...

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Ontology based mining of pathogen–disease associations from literature

Ontology based mining of pathogen–disease associations from literature

... pathogen–disease associations which needs to be cre- ated and could also be useful for developing machine learning based ...covering disease and pathogen names such as the Experimental Factor ...

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Probability-based collaborative filtering model for predicting gene–disease associations

Probability-based collaborative filtering model for predicting gene–disease associations

... In this study, we proposed a probability-based collabora- tive filtering model (PCFM) for prediction of gene–disease relationships. As neighborhood models can not cover over- all demonstrated information, latent ...

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Challenges in the construction of knowledge bases for human microbiome-disease associations

Challenges in the construction of knowledge bases for human microbiome-disease associations

... unique disease annotations, covering only 1082 unique disease concepts, whereas the Comparative Toxicogenomics Database (CTD) MEDIC dictionary contains 11,885 unique disease concepts (1082/11,885 = ...

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Inferring drug-disease associations based on known protein complexes

Inferring drug-disease associations based on known protein complexes

... drug-disease associations is critical in unveiling disease mechanisms, as well as discovering novel functions of available drugs, or drug ...and disease are constructed, where we assign ...

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Prediction of CircRNA-Disease Associations Using KATZ Model Based on Heterogeneous Networks

Prediction of CircRNA-Disease Associations Using KATZ Model Based on Heterogeneous Networks

... Circular RNAs (circRNAs) are a large group of endogenous non-coding RNAs which are key members of gene regulatory processes. Those circRNAs in human paly significant roles in health and diseases. Owing to the ...

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An Update on the Streptococcus bovis Group: Classification, Identification, and Disease Associations

An Update on the Streptococcus bovis Group: Classification, Identification, and Disease Associations

... clinical microbiology laboratories. Studies published to date sug- gest that the accuracy of MALDI-TOF MS is highly dependent on the system used and the databases employed. For these systems, the responsibility falls on ...

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Discovery of Gene disease Associations from Biomedical Texts

Discovery of Gene disease Associations from Biomedical Texts

... The paper aims to automatically identify the associations of the human genetic diseases and genes from the biomedical literatures. We first use the MBSP system to get the parsing information. Then we apply a rule ...

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Disease associations depend on visit type: results from a visit-wide association study

Disease associations depend on visit type: results from a visit-wide association study

... and disease phenotypes extracted from the ...– disease associations within EHRs linked with Biobanked genetic data ...structured disease codes and investi- gated genes associated with these ...

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Cerebral and Coronary Vasculature in Disease Associations and Dissociations in the South Indian Population.

Cerebral and Coronary Vasculature in Disease Associations and Dissociations in the South Indian Population.

... cerebrovascular disease (CVD) with the aim to decide on early neurological ...Significant disease was found in only ...vessel disease including internal carotids but not so much with large ...vessel ...

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MicroPro: using metagenomic unmapped reads to provide insights into human microbiota and disease associations

MicroPro: using metagenomic unmapped reads to provide insights into human microbiota and disease associations

... organism associations for disease prediction, it has been shown that the oral microbiota can influence the gut microbiome and has been detected in the stools of patients with cirrhosis ...

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Inherited deficiency of the second component of complement  Rheumatic disease associations

Inherited deficiency of the second component of complement Rheumatic disease associations

... rheumatic disease including 137 with systemic lupus erythematosus (SLE), 274 with juvenile rheumatoid arthritis, and 134 with rheumatoid ...of disease and less antinuclear antibody when compared with the C2 ...

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Complement regulator CD46: genetic variants and disease associations

Complement regulator CD46: genetic variants and disease associations

... 60 disease-associated mutations in MCP have now been ...microangiopathic-based disease, atypical hemolytic uremic syndrome (aHUS), but new putative links to systemic lupus erythematosus, glomerulonephritis, ...

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Clinical associations between gout and multiple sclerosis, Parkinson’s disease and motor neuron disease: record-linkage studies

Clinical associations between gout and multiple sclerosis, Parkinson’s disease and motor neuron disease: record-linkage studies

... of disease associations ...neurological disease). As a check, we estimated the risk of each neurological disease in the reference cohort to ensure that it does not include conditions that have ...

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DachsLife 2015: an investigation of lifestyle associations with the risk of intervertebral disc disease in Dachshunds

DachsLife 2015: an investigation of lifestyle associations with the risk of intervertebral disc disease in Dachshunds

... A previous study identified moderate, rather than in- frequent, stair climbing was associated with reduced IVDD risk in SWH Dachshunds [19], the variety at low- est risk in our study. The current study also found a trend ...

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Associations between Virulence Factors of Shiga Toxin ProducingEscherichia coli and Disease in Humans

Associations between Virulence Factors of Shiga Toxin ProducingEscherichia coli and Disease in Humans

... Among over 100 serotypes that have been recovered from humans, serotypes O157:H7 and O157:H2 clearly represent the majority of isolates associated with disease. However, STEC or- ganisms of many other serotypes ...

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Leptospira seroprevalence and associations between seropositivity, clinical disease and host factors in horses

Leptospira seroprevalence and associations between seropositivity, clinical disease and host factors in horses

... Multivariable logistic regression was used (when sero- prevalence was > 8%) to model two outcomes: titres ≥ 1:100 to the agents sv Bratislava and Icterohaemorrhagiae for associations with possible risk factors. ...

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Motor phenotypes, medication and mood: further associations with impulsive behaviours in Parkinson's disease

Motor phenotypes, medication and mood: further associations with impulsive behaviours in Parkinson's disease

... [16] Christenson GA, Faber RJ, de Zwaan M, Raymond NC, Specker SM, Ekern MD, Mackenzie TB, Crosby RD, Crow SJ, Eckert ED, et al. (1994) Compulsive buying: descriptive characteristics and psychiatric comorbidity. J Clin ...

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Associations of Streptococcus suisSerotype 2 Ribotype Profiles with Clinical Disease and Antimicrobial Resistance

Associations of Streptococcus suisSerotype 2 Ribotype Profiles with Clinical Disease and Antimicrobial Resistance

... observed associations between ribotype profiles and clinical-pathological observations because the clinical-patho- logical observations could partly be a result of different infec- tion ...

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