disease gene loci identification
Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline
... unrecognized loci related to two clinically important pulmonary func- tions in a cross-sectional analysis ...any disease manifesta- tions, or other respiratory diseases such as asthma, or they did not have ...
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Use of Chromosome Segment Substitution Lines for the Identification of Multiple Disease Resistance Loci in Maize.
... maize gene affecting one of these aspects of pathogenesis shared by the three pathogens could confer resistance to multiple diseases (Balint-Kurti et ...pairwise disease resistance trait combinations after ...
248
Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice
... uniform disease progression in inbred animals, polycystic kidney disease (PKD) progression within human families can be highly ...trait loci map- ping of 114 selected pcy/pcy mice (68 with the mild ...
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B-cell malignancies: capture-sequencing strategies for identification of gene rearrangements and translocations into immunoglobulin gene loci
... Notes: (A) Summary of the different B-cell neoplasms, the normal cellular counterparts they arise from, and the main translocations involving the iGH locus they harbor (the disease-defining translocations are ...
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Rule-based induction method for haplotype comparison and identification of candidate disease loci
... as gene expression studies and large scale sequencing ...putative disease-asso- ciated regions, and help focus the analysis of whole gen- ome or exome sequencing data to particular loci; a key ...
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Identification of novel genetic susceptibility loci for Behçet's disease using a genome wide association study
... We have identified 10 possible candidate genes based on the unbiased genome-wide pooling association study. Individual case-control genotyping using TaqMan SNP Genotyping Assays confirmed the genetic association between ...
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Identification of bakanae disease resistance loci in japonica rice through genome wide association study
... Bakanae disease, caused by seed-borne Fusarium species, mainly ...rice disease whose importance is considerably increasing in several rice growing countries, leading to incremental production ...the ...
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Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients
... β-thalassemia disease severity and pharmacogenomic biomarkers for HU treatment efficacy in β-type hemoglobinopathy ...genomic loci that have been reported to increase HbF levels could be considered as phar- ...
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The Fine Mapping of Two Black Shank Resistance Loci and Identification of a Hybrid Lethality Gene in Tobacco.
... Black shank, caused by the oomycete Phytophthora nicotianae, is among the most important diseases impacting field production of tobacco (Nicotiana tabacum L.). Genetic resistance is the most economical means of managing ...
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Analyzing the most frequent disease loci in targeted patient categories optimizes disease gene identification and test accuracy worldwide
... optimal disease testing in regional laboratories (Additional file 1: Table ...specific gene mutations reported in these descendents of a few score of ...
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Identification of 19 loci for reproductive traits in a local Chinese chicken by genome-wide study.
... Genome-wide association studies (GWAS) are used to identify SNPs and functional genes that affect quantitative traits (Jin et al., 2015). This technique is more efficient at identifying genetic characteristics for ...
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Physical and transcriptional mapping studies within the retinitis pigmentosa critical region on chromosome 7p
... autoimmune disease Stiff-Man syndrome, as it was discovered that a subset of patients with this disease accompanied by breast cancer seem to be positive for autoantibodies directed against amphiphysin ...
286
Hominid retrotransposons as a modulator of genomic function
... reporter gene constructs (Michelhaugh et ...a gene altering to take advantage of the transcription factor complement in a cell to expand or lay extra complexity upon the gene’s ...
267
ON THE TIME FOR GENE SILENCING AT DUPLICATE LOCI
... The agreement in Table 6 between the approximate analytic results and LI’S simulations is reasonable and shows (in conjunction with Tables 3 and 4) that when mutation is lo[r] ...
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The evolution of haemoglobin gene loci in amniotes
... Our prediction of nine pHS for the platypus β -globin cluster identified one region (pHS#2) that shared matches to two transcription factor binding site motifs within the therian HS3. However, it did not cause any ...
206
A STUDY OF LINKAGE DISEQUILIBRIUM IN BRITISH POPULATIONS OF DROSOPHILA SUBOBSCURA
... Relations between gene arrangements and closely linked e n z y m e loci: There are strong associations between allele frequencies and gene arrangements at three loci (LAP, PEPT[r] ...
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Nuclear envelopathies: a complex LINC between nuclear envelope and pathology
... LMNB1 gene, very few mutations in LMNB2 have been associated with human ...LMNB2 gene is a case of acquired partial lipodystrophy, also called Barraquer-Simons syndrome ...This disease is a rare ...
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Constructing an integrated gene similarity network for the identification of disease genes
... out disease gene is ranked as top 1 among the control gene set, we consider it a successful ...control gene sets in all validation ...of disease genes that are ranked above a particular ...
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Identification, Characterization, and Phylogenetic analysis of Pigeon pea (Cajanus cajan L. Mill sp.) Resistance Gene Analogs using PCR cloning and in silico methods
... The relationships between RGA gene nucleotide sequences were also examined. Using five RGA-specific primer sets, 40 sequences were amplified and sequenced from the eight pigeonpea genotypes. Phylogenetic analysis ...
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Identification of Linked Markers for Delayed Fruit Ripening in Tomato Using Simple Sequence Repeat (SSR) Markers
... nor loci on chromosomes 5 and 10 spanning was constructed by using combination of bulked segregation analysis as well as classical restriction fragment length polymorphism (RFLP) (Giovannoni et ...response ...
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