Disease progression
Rab11 in Disease Progression
... of Rab11 function in fibroblasts of HD patients has been observed to perturb vesicle formation from recycling endosomes. Rab11 is involved in synaptic dysfunction prior to the onset of HD symptoms, with the aim of ...
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Crevicular fluid biomarkers and periodontal disease progression
... noted for many permutations of the different parameters evaluated. Pla- que pathogens provided good sensi- tivity and specificity for prediction of PDP, 63% (95% CI = 49, 77) and 69% (95% CI = 55, 83) respectively. A ...
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Association of specific biotypes in patients with Parkinson disease and disease progression
... Parkinson’s Progression Markers Initiative (PPMI; ...ported disease-spreading ...early disease and might predict the type of symptoms or disease pro- gression that a patient will ...of ...
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The effect of immune responses in HCV disease progression
... the disease progression, we have proposed a mathematical model which includes healthy liver cells, infected liver cells, virus population and CTL ...for disease free as well as endemic ...the ...
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Marital distress and disease progression: A systematic review
... or disease progres- ...and disease progression appear to have bidirectional influence on each ...on disease progression among spous- es with ...and disease progression ...
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Calprotectin as a Biomarker for Melioidosis Disease Progression and Management
... Infections of Macaca mulatta and other NHPs faithfully replicate human melioidosis, and these laboratory disease models can be used to study many aspects of infection (13). We first used an M. mulatta model of ...
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Predictors of disease progression in HIV infection: a review
... affecting disease progression can aid treatment commencement and therapeutic monitoring ...for disease stage and progression ...and disease progression remains ...of ...
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Effective chronic disease progression model
... Understanding disease progression can help investigators detect healthcare insurance frauds early ...Existing disease progression methods often ignore complex relations, such as the time -gap ...
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Riemannian geometry learning for disease progression modelling
... a disease is key to understand its progression as well as to design prognosis and early diagnostic ...a disease is more informative than static observations of the symptoms, especially for ...
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Overlap between age-at-onset and disease-progression determinants in Huntington disease
... onset, disease progression, and age at death, the only possibility that would allow for a disease duration independent of CAG repeat size 9 would be a dif- ferent neuroanatomical basis for, on the ...
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A retrospective analysis of hand tapping as a longitudinal marker of disease progression in Huntington’s disease
... of disease progression including grip force and tongue protrusion ...to disease onset and in manifest patients in comparison to controls ...to disease onset in premanifest patients ...
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Urinary miR 196a predicts disease progression in patients with chronic kidney disease
... and disease progression of FSGS patients, we set the progression to ESRD or 40% eGFR reduction as composite end points, which reflect the current concept of clinical trial end points in CKD ...of ...
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The Chronic Kidney Disease Model: A General Purpose Model of Disease Progression and Treatment
... simulating disease progression while accounting for uncertainties in out- comes using a range of possible ...of disease progression which are conditional on patient character- istics must be ...
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How to detect disease progression in pulmonary arterial hypertension
... PAH disease progression and most tools and variables used to detect clinical deterioration are reflecting RV ...detect disease progression both at diagnosis and during follow-up of patients ...
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The Role of SNCA Rep1 Microsatellite in Parkinson’s Disease Progression
... study showed that a variant of α-synuclein gene (SNCA), namely the 263bp allele of Rep1 was associated to faster motor progression in PD. On the contrary, a recent report failed to detect a detrimental effect of ...
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Comparison of disease progression subgroups in idiopathic pulmonary fibrosis
... of disease course sub- groups as applied here, reported that patients with a rapid disease course had less gastro-esophageal reflux and more diabetes and lung cancer than patients with a slow disease ...
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Clinical Predictors of disease progression in Parkinson's disease
... for disease progression patterns in PD, and important strengths of our study are related to the large cohort size, the long follow-up duration and the limited ...
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Hypoxemia in patients with COPD: cause, effects, and disease progression
... Abstract: Chronic obstructive pulmonary disease (COPD) is a leading cause of death and dis- ability internationally. Alveolar hypoxia and consequent hypoxemia increase in prevalence as disease severity ...
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Applications of miRNAs in cardiac development, disease progression and regeneration
... proliferation, migration and specification into appropriate cell types [8]. These structural defects do not repair them- selves as the cardiac stem cells terminally differentiate and exit the cell cycle postnatally and ...
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Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease
... We next examined tau pathology, which is a pathological hallmark of AD and prominent in our mutant AD mouse model. Hyperphosphorylated tau forms insoluble aggregates that pro- mote NFTs. The expression of total tau ...
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