Dismutase Gene
Susceptibility of Diabetics with Superoxide Dismutase Gene 2 Polymorphism to Vascular Complications.
... superoxide dismutase gene 2 Ala16Val polymorphism and cardiovascular complications in diabetes ...superoxide dismutase gene causing reuced superoxide dismutase activity can accelerate ...
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A second superoxide dismutase gene in the medfly, Ceratitis capitata.
... was isolated from a medfly third-instar cDNA library, using as a probe a PCR fragment amplified from adult. cDNA[r] ...
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Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene
... The thought that microglial neuroinflammation pro- motes motor neuron degeneration can be traced back to the initial descriptions of activated microglia in human ALS tissues [16]. Since then, the idea of detrimental neu- ...
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Myocardial Protective Effect of Extracellular Superoxide Dismutase Gene Modified Bone Marrow Mesenchymal Stromal Cells on Infarcted Mice Hearts
... superoxide dismutase (ecSOD) is a unique scavenger of superoxide anions and a promising target of gene therapy for ischemia/reperfusion injury ...conventional gene therapies have limitation in ...
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MODULATION OF NITRIC OXIDE SYNTHASE AND SUPEROXIDE DISMUTASE GENE EXPRESSION BY ALTERED THYROID LEVELS IN ADULT RAT BRAIN
... Superoxide dismutase acts as a double edged sword; it scavenges superoxide radical by dismutating it to hydrogen peroxide which can freely move across cell membranes and cause oxidative modification [26] ...
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Molecular and Biochemical Study of Superoxide Dismutase Gene Polymorphisms in Egyptian Patients with Type 2 Diabetes Mellitus with and without Retinopathy
... superoxide dismutase and its genotype distribution in diabetic patients with and without retinopathy, and hence the need for antioxidant supplements to delay the severity of diabetic ...
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Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study
... Four studies examined the association of the Val-9Ala pol- ymorphism with breast cancer risk, with mixed results [17- 20]. Two hospital-based case–control studies found a moderate elevation in risk among women carrying ...
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Detection of Coxiella burnetti by DNA amplification using polymerase chain reaction
... burnetii isolates by PCR in tissue culture material and in direct patient specimens heart valves using oligonucleotide primers derived from the superoxide dismutase gene sequence of C.. [r] ...
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Oxidative Damage and Mutagenesis in Saccharomyces cerevisiae: Genetic Studies of Pathways Affecting Replication Fidelity of 8-Oxoguanine
... ABSTRACT Oxidative damage to DNA constitutes a major threat to the faithful replication of DNA in all organisms and it is therefore important to understand the various mechanisms that are responsible for repair of such ...
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Associations between functional polymorphisms in antioxidant defense genes and urinary oxidative stress biomarkers in healthy, premenopausal women
... Cai Q, Shu XO, Wen W, Cheng JR, Dai Q, Gao YT, Zheng W (2004) Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast ...
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Superoxide Dismutase: Therapeutic Targets in SOD Related Pathology
... Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by death of motor neurons leading to muscle wasting, paralysis, and death, usually within 2 - 3 years of symptom onset. The ...
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Comparative Analysis of Structure and Sequences of Oryza sativa Superoxide Dismutase
... The phylogenetic tree (Figure 1) shows that Cu-Zn SODs evolved independently in Oryza sativa SODs. Short distance between branch points of the Mn SODs and Fe SODs suggests a common phylogenetic origin and likely frequent ...
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Redox signaling in pathophysiology of hypertension
... superoxide dismutase; NE: Norepinephrine; NF- κ B: Nuclear factor kappa B; NGF: Nerve growth factor; NO: Nitric oxide; NOS: Nitric oxide synthase; Nrf2: Nuclear transcription factor E2-related factor 2; O2 • – : ...
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Regulation of lung oxidative damage by endogenous superoxide dismutase in sepsis
... sod3 gene are more sensitive to lethal levels of hyperoxia ...sod3 gene or are treated with a SOD mi- metic have improved lung compliance, decreased neutrophil influx, release of proin- flammatory ...
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Erythrocyte superoxide dismutase as a biomarker of septic acute kidney injury
... AKI: acute kidney injury; AKIN criteria: acute kidney injury network criteria; APACHE II score: Acute Physiology and Chronic Health Evaluation II score; CI 95 %: confidence interval 95 %; CKD: chronic kidney disease; ...
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Determination of catalase, peroxidase, and superoxide dismutase within the genus Legionella
... This medium has been found to give the maximutn production by Legionella cells of both catalase and peroxidase, although Escherichia and Pseudomonas strains which have been grown on this[r] ...
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Superoxide dismutase in Bacteroides fragilis and related Bacteroides species
... Superoxide dismutase SOD activity was demonstrated in cell-free extracts of Bacteroides fragilis, Bacteroides vulgatus, Bacteroides distasonis, Bacteroides ovatus, and Bacteroides thetai[r] ...
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Comparative Protein Modeling of Superoxide Dismutase Isoforms in Maize.
... Sequence homology in grouping reflected the strong similarities in the genetic patterns of these two maize and Arabidopsis plants. However, many sequence-based families are polyspecific, which means they include genes ...
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Protective Role of Superoxide Dismutase against Diabetogenic Drugs
... Copper-zinc superoxide dismutase (SOD) is present in relatively high concentrations in the b-cells of human islets. The activity of the extracted enzyme is partially inhibited upon incubation with the diabetogenic ...
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The crystal structure of superoxide dismutase from Plasmodium falciparum
... A homology model (see Additional file 1) of the mito- chondrially targeted PfFeSOD2 was derived using the cytosolic PfFeSOD structure solved here. The cytosolic PfFeSOD is the closest in sequence of any dismutase ...
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