DNA-mediated Charge Transport
Investigating DNA-Mediated Charge Transport by Time-Resolved Spectroscopy
... in DNA is DNA-mediated charge transport ...obases, DNA can serve as a bridge in long-range electron transfer (ET) ...and DNA, 11 DNA-mediated CT results in ...
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Regulation of Wild Type and Mutant p53 through DNA mediated Charge Transport
... for DNA binding to ...the DNA-damaging small molecule ...Although DNA binding is retained when cysteines in p53 (that are not coordinated to the zinc ion) are mutated to serine, 13 WS-1 cells lose ...
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Electrochemical sensors based on DNA mediated charge transport chemistry
... the DNA duplexes on gold electrode surfaces is varied to establish the importance of the length, orientation and flexibility of the linker in forming densely packed DNA ...to DNA by intercalation ...
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DNA Mediated Charge Transport Signaling Within the Cell
... that DNA-mediated signaling is used as a general mechanism by which DNA repair proteins with 4Fe-4S clusters locate damage within ...cluster, DNA-modified electrochemistry was used to ...
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Fundamental mechanisms and biological applications of DNA mediated charge transport
... the DNA double helix can serve as an efficient medium for charge transport ...from DNA-mediated charge transport reaction has particular relevance in the field of aging ...
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DNA Mediated Charge Transport Devices for Protein Detection
... proteins, DNA, and RNA, is vital for fundamental research as well as clinical ...Electrochemical DNA platforms are simple, sensitive, and do not require complex target labeling or expensive ...to DNA ...
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DNA-Mediated Charge Transport for Long-Range Sensing and Protein Detection
... research. In particular I am grateful to the many Barton group members who collaborated on work with me or provided me with helpful guidance. I worked closely with Jason Slinker on several aspects of this work and he ...
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DNA Mediated Charge Transport in DNA Repair
... this DNA-mediated CT process can be considered as a scan of the integrity of intervening DNA, since DNA-mediated CT can only proceed through a well stacked ...the ...
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Activation of Transcription from a Distance: Investigations on the Oxidation of SoxR by DNA Mediated Charge Transport
... on DNA binding of ~500 mV is striking but ...of DNA (11). Since the structures of Endo III with and without DNA were known and showed no significant distortion in the protein (52-54), ...
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DNA-mediated Charge Transport in a Biological Context: Cooperation among Metalloproteins to Find Lesions in the Genome
... that DNA-mediated CT can trigger MutY, we have examined yet another system that includes a metallo transcription factor, ...to DNA (44). Due to the shift seen upon binding to DNA, we ...
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Exploring DNA Mediated Charge Transport with Fast Radical Traps
... in DNA, product yields for different photooxidants scale inversely to the propensity for BET, 13 and attenuating BET, both between the hole donor and the oxidized bridge and between the hole donor and oxidized ...
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DNA-Mediated Hole and Electron Transport
... First and foremost, I must thank my research advisor, Professor Jacqueline K. Barton. She has always been a great mentor to me. She is the person who led me into the fascinating world of DNA-mediated ...
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Electrochemical studies of electron transfer in DNA films with covalently tethered intercalators
... double-stranded DNA probe with a 6-base overhang (probe ...long DNA duplex, which has a nick in sugar-phosphate backbone of each strand, is formed on the ...affect DNA mediated charge ...
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Spectroscopic characterization of DNA-mediated charge transfer
... the DNA double helix 3 ...long-range charge transport was demonstrated 12 ...duplex DNA self-assembled monolayers on gold 14 ...to charge transfer in DNA 18 ...in DNA 24 ...
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Effect Of Orientation On Charge Transport In Molecular Junctions
... electron transport characteristics of interface between Au/Pen, and Si/Pen is done, further to model the electronic properties of metal/molecule interface (Fig 1), and for metal/molecule/metal, two probe systems ...
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Photoelectrode Optimization of Zinc Oxide Nanoparticle Based Dye-Sensitized Solar Cell by Thermal Treatment
... mass transport between FTO substrate and ZnO layer that stimulates oxygen atoms diffusing into both the layers, resulting in a higher sheet resistance of ...
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Investigation of charge transport in single OPE3 molecules
... The orbitals in Figure 2.2 that have a red shaded area are fully occu- pied, whereas the blue shaded areas refer to orbitals that are completely unoccupied. The HOMO level is filled by the left lead, but simultaneously ...
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Polymicrobial Infection and Bacterium Mediated Epigenetic Modification of DNA Tumor Viruses Contribute to Pathogenesis
... There is extensive evidence demonstrating the critical role of bac- terial products in the modulation of viral epigenomes (summa- rized in Table 1). Regardless of tumor virus type or cell type, bac- teria are associated ...
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Microscopic modeling of charge transport in sensing proteins
... the protein network analogue becomes a set of intercross- ing spheres of radius R C . In principle, all the values of R C from zero to tens of nanometers (the protein size) are possible. Actually, this value depends on ...
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BRAIN DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW ON RECENT EXPERIMENTAL AND CLINICAL FINDINGS
... BBB & Drug Delivery to the Brain: The BBB drug delivery problem can be solved, but this requires new approaches to this area of pharmaceutics. The old ways of drilling a hole in the head for trans- cranial brain drug ...
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