DNA rearrangements
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
... genomic DNA [15] and, typically, generate a new L1 insertion via target- primed reverse transcription (TPRT) ...pre-existing DNA double strand breaks, producing inser- tions that lack TPRT hallmarks ...in ...
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Role of Histone Deacetylation in Developmentally Programmed DNA Rearrangements in Tetrahymena thermophila
... Effects of TSA treatment on conjugating cells. Since the effects of TSA treatment on the life cycle of Tetrahymena have never been reported, we investigated the process of conjuga- tion in the presence of TSA. Vegetative ...
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LIA4 Encodes a Chromoshadow Domain Protein Required for Genomewide DNA Rearrangements in Tetrahymena thermophila
... to DNA damage, the authors hypothesized that the ␥ H2AX appears in developing macronuclei after double- strand breaks are introduced upon IES ...for DNA rearrangements. (A) DNA rearrangement ...
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Sequence requirements for DNA rearrangements induced by the terminal repeat of herpes simplex virus type 1 KOS DNA.
... If the recombination event that gave rise to the inversion fragment occurred by cleavage-ligation at the position of site-specific cleavage directed by pacl case 1, then the 5'-flanking [r] ...
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DNA rearrangements in organ-specific variants of polyomavirus JC strain GS.
... ATG is the start codon for the early and late genes, and AT is the TATA box; 58 bp and 46 bp are the lengths of gene segments that were absent in the control region of the brain-derived [r] ...
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DNA REARRANGEMENTS ASSOCIATED WITH REVERSION OF BACTERIOPHAGE MU-INDUCED MUTATIONS
... To study the process of Mucts X excision from the lacZ gene, we have analyzed large numbers of Mel+ (imprecise excision events) and Lac+ (precise excision events) revertants [r] ...
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Programmed DNA Rearrangements During Differentiation: Immunoglobulin Class Switching
... ABSTRACT 'A preliminary analysis of several heavy chain variable V and constant region C gene segments from sperm undifferentiated and myeloma differentiated DNA has revealed the followi[r] ...
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Tudor Nuclease Genes and Programmed DNA Rearrangements in Tetrahymena thermophila
... of DNA elimination of some deletion elements are very precise, while others are more vari- able, and how these borders are determined is not well under- stood ...Tetrahymena DNA. However, “misplaced” ...
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Rearrangements of the DNA in Carbon Ion-Induced Mutants of Arabidopsis thaliana
... GACCAAG-3⬘; USP2, 5⬘-CTTCACTGCCGCTTCTTTGC-3⬘; two contained inversions and/or translocations, and and USP3, 5⬘-CGATGTCCTGTCTGGTGTCC-3⬘, and the arbi- one had a point-like mutation (Shikazono et al. 1998b). trary ...
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Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development
... that DNA transposases rely on cellular DNA repair to mediate DNA rearrangements, including ligation of DNA target sites ...NHEJ DNA repair machinery, involving the heterodimeric ...
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Molecular analysis of variant plasmid forms of a bivalent Salmonella typhi Shigella sonnei vaccine strain
... Since restriction fragment analysis had indicated that DNA rearrangements might be occurring in the vaccine plasmid, large plasmid DNA isolated from the clonal variants was digested with[r] ...
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Gene Loss, Silencing and Activation in a Newly Synthesized Wheat Allotetraploid
... 1-kb DNA Southern blot analysis of the transcripts showing al- ladder molecular weight marker ...with DNA rearrangements or with changes in cytosine methylation, a Southern blot In these cases it is ...
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The structure of adenovirus type 12 DNA integration sites in the hamster cell genome.
... Ad12 DNA and hamster cellular ...Ad12 DNA (map in ...the DNA sequence determined and partly presented in panel ...Ad12 DNA sequence as position ...Ad12 DNA sequence (italic characters) ...
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IgH gene rearrangements as plasma biomarkers in Non- Hodgkin’s Lymphoma patients
... Enthusiasm has been growing for risk-adapted therapy in the treatment of diffuse large B cell lymphoma. Mid cycle FDG PET has been used to guide decisions on switching chemotherapy regimens and to select patients for ...
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Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from a chronically infected liver.
... Southern blot analysis of the normal cellular flanking sequences, using flanking sequence probes from the clone, showed that no detectable rearrangements of cellular DNA less than 50 bas[r] ...
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Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA.
... Extensive rearrangements of HPV16 sequences occur in HPV16-transfected human cells; the presence of bands greater than 7.9-kbp in the BamHI-digested DNA from HPV16-transfected human cell[r] ...
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Defects in DNA Lesion Bypass Lead to Spontaneous Chromosomal Rearrangements and Increased Cell Death
... more DNA lesions become substrates for dHJ pathways upon elimination of Mph1 and ...aberrant DNA structures may not be the only cause for Mec3-dependent cell cycle arrest of mph1 ⌬ srs2 ⌬ ...stability. ...
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Chato, a KRAB zinc finger protein, regulates convergent extension in the mouse embryo
... In Xenopus and zebrafish embryos, elongation of the anterior-posterior body axis depends on convergent extension, a process that involves polarized cell movements and is regulated by non-canonical Wnt signaling. The ...
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Rearrangements of steroids
... Although a large number of epoxide rearrangemc.:'!nts have been found to lead to the formation of these products of backbone migration, the factors influencing the relative yields of the[r] ...
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Rearrangements of steroids
... TONE adduct of 9p-cholesm-5, 7-dien-5p-o1 To a solution of 9f-cholestQ~,7-dien-5p-ol 85b 549 mg in dichloromethane was added tetracyanoethylene TONE 152 mg and the mixture stirred at roo[r] ...
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