dopamine D1 receptor
Association of dopamine D1 receptor gene polymorphism with schizophrenia: a meta-analysis
... DRD1, dopamine receptor 1, dopamine D1 receptor, dopamine receptor D1, schizophrenia, polymorphism, and ...
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Dopamine D1 receptor-mediated NMDA receptor insertion depends on Fyn but not Src kinase pathway in prefrontal cortical neurons
... study D1 receptor activation-mediated NR2B expression in cultured PFC neurons, the cultures were treated for 10 min with DMSO ...selective dopamine D1 receptor agonist SKF-81297 (10 ...
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Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice
... beta receptor (1:50, Santa Cruz), goat anti-ionized calcium-binding adapter molecule 1 (Iba 1, 1:200, Abcam), and rabbit anti-MPO (1:100, Abcam) at 4 °C ...
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Impaired dopamine D1 receptor-mediated vasorelaxation of mesenteric arteries in obese Zucker rats
... ceptor expression and ability to inhibit Na, K-ATPase and Na,H-exchanger activities in renal proximal tubules [13,28,30]. These authors suggested that the renal dopa- minergic dysfunction in obese Zucker rats is acquired ...
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Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells
... the D1 receptor agonist SKF-38393 could significantly enhance Runx2 expression compared with the expression observed in the control group; however, the D2 receptor agonist pramipexole seemed to have ...
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Effects of dopamine D1 receptor blockade on the ERG b- and d-waves during blockade of ionotropic GABA receptors
... FS. Dopamine modulates GABAc receptors mediating inhibition of calcium entry into and transmitter release from bipolar cell terminals in tiger salamander ...A. Dopamine and serotonin modulate human GABA ρ 1 ...
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PSD 95 expression controls l DOPA dyskinesia through dopamine D1 receptor trafficking
... PSD-95 and shPSD conditions, respectively (n = 121–2,695 tra- jectories; Figure 5G). In addition, the D1R diffusion pattern was examined by plotting the mean squared displacement (surface explored by the receptor) ...
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Genetic association between the dopamine D1-receptor gene and paranoid schizophrenia in a northern Han Chinese population
... To determine the role of DRD1 genetic polymorphisms as a risk factor for schizophrenia, we undertook a case-control study to look for an association between the[r] ...
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Dopamine D1 receptor stimulation modulates the formation and retrieval of novel object recognition memory: role of the prelimbic cortex
... Comparison between the systemic drug studies (experiments 1 – 3) provides the temporal resolution to distinguish effects at encoding versus retrieval in the NOR procedure. Since both encoding and retrieval were affected, ...
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The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium
... A68930 phosphorylates CREB through PKA and/or MEK in 16HBE14o- cells and NCI-H292 cells. A68930 (1 μM, 20 min) significantly increased phosphorylation of CREB in 16HBE14o- cells (P < 0.05, n = 3) and NCI- H292 cells ...
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Dopamine D1 receptor involvement in latent inhibition and overshadowing
... Latent inhibition (LI) manifests as poorer conditioning to a stimulus that has previously been experienced without consequence. There is good evidence of dopaminergic modulation of LI, as the effect is reliably disrupted ...
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Methamphetamine-induced changes in the striatal dopamine pathway in μ-opioid receptor knockout mice
... of dopamine receptors in the stria- tum: D1 and ...express dopamine D1 receptors whereas most striatopallidal neu- rons express dopamine D2 receptors ...of dopamine D1 and ...
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Dopamine D1-D5 receptor protein immunohistochemistry in dog pial arteries
... anti-dopamine D1 receptor protein antibody alone (a) or pre-adsorbed with the corresponding blocking peptide ...D2 receptor antibody alone (c) or pre- adsorbed with the corresponding ...
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Role of the nervous system in cancer metastasis
... its receptor tropomyosin related kinase A (TrkA) [61, 72, ...its receptor GFRα1 stimulates PNI via GDNF-(Ret proto-oncogene) RET signaling pathway ...
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Original Article Dopamine receptor expression on primary osteoblasts and bone marrow mesenchymal stem cells of rats
... anti-dopamine receptor D1R polyclonal anti- body (1:400; Abcam, Cambridge, MA, USA) or rabbit anti-dopamine receptor D2R polyclonal antibody (1:400; Abcam, Cambridge, MA, USA) at 4°C overnight ...
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Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non atrophying and atrophying conditions
... 81297 treatment on both casted and non-casted TA and MG muscles, the magnitude of the reduction in muscle mass loss in the casted leg muscle (3.2 mg averaged difference in muscle mass between SKF 81297 and vehicle ...
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Comparative pharmacological characterization of D1 like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatus suggests pleiotropic signaling in mosquito vector lineages
... mine receptors (DARs) show promise as a new class of insecticides against the mosquito vectors Aedes aegypti and Culex quinquefasciatus [4–7]. Several antagonists are potent inhibitors of the Ae. aegypti AaDOP2 and C. ...
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Cocaine Self-Administration: Adaptations to the Glutamatergic System and Consequences for Offspring Emotional Control
... surface receptor expression would not be possible without accessory proteins to aid in the trafficking and stabilization of GluA1 subunits (Anggono and Huganir, 2012; Lisman et ...
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Modulation of spinal motor networks by astrocyte derivsed adenosine is dependent on D1 like dopamine receptor signalling
... in locomotor networks, adenosine (75 M) (Witts et al. 2012) was bath applied to isolated spinal cords in which locomotor- related activity was induced by bath-applied NMDA and 5-HT. Importantly, descending dopaminergic ...
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Dopamine D3 receptor and GSK3β signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice
... subsequent appearance of bipolar symptoms [6, 7]. DAT-knockdown (KD) mice show a 90% decrease in DAT expression and a 70% increase in extracellular DA concentration in the striatum [8]. As a result, DAT-KD mice exhibit ...
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