dopamine D2 receptor
Associations between dopamine D2 receptor gene polymorphisms and schizophrenia risk: a PRISMA compliant meta-analysis
... Method: The PubMed, Embase, and China National Knowledge Infrastructure databases were searched to identify relevant literature published up to February 2016. The allele contrast model was used. Stata software was used ...
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Relationship between calorie intake, physical activity, and dopamine D2 receptor Taq1A gene polymorphism in normal-weight, overweight, and obese students of the faculty of medicine of university of Sumatera Utara
... and dopamine D2 receptor Taq1A (DRD2 Taq1A) gene polymorphism in normal- weight, overweight, and obese students of the Faculty of Medicine of University of Sumatera, ...
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THE INHIBITORY EFFECT OF ASCORBIC ACID ON APOMORPHINE-INDUCED LICKING BEHAVIOR IS MEDIATED BY DOPAMINE D2 RECEPTOR MECHANISMS IN RAT
... and dopamine receptors ...different dopamine receptor antagonists on apomorphine- induced licking behavior were ...of dopamine D1 receptor antagonist, SCH 23390 ...of dopamine ...
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Dopamine D2 receptor functional selectivity as a mechanism of atypical antipsychotic drug action
... that receptor is ...in receptor density and/or the strength of stimulus-response ...a receptor to the same degree as the endogenous ligand for that ...specific receptor should antagonize every ...
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Regulation of Akt and Wnt signalling by the dopamine D2 receptor and metabotropic glutamate receptor 2/3
... Wnt proteins are secreted glycoproteins that bind to Frizzled (Fz) receptors and the co-receptor low-density lipoprotein receptor-related protein 5/6 (LRP5/6). This event can activate one or more of the 3 ...
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The expression profile of Dopamine D2 receptor, MGMT and VEGF in different histological subtypes of pituitary adenomas: a study of 197 cases and indications for the medical therapy
... to dopamine agonists is related to the activity of the D2 receptor which belongs to the family of G protein- coupled receptors and acts through AMP cyclase en- zyme inhibition ...that D2 ...
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A thieno[2,3 d]pyrimidine scaffold is a novel negative allosteric modulator of the dopamine D2 receptor
... of dopamine binding and/or ...of dopamine efficacy, we identified analogues of 1 that displayed modulatory effects upon dopamine affinity ...both dopamine affinity and efficacy ...with ...
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Discovery of a novel class of negative allosteric modulator of the dopamine D2 receptor through fragmentation of a bitopic ligand
... G protein-coupled receptors (GPCRs) are the largest superfamily of cell surface receptors and are targeted by approximately one third of current medicines. 1 There has been an increasing interest in targeting allosteric ...
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Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?
... with dopamine release mea- sured indirectly by displacement of radio ligands of dopamine D2 receptors in this brain area 21 ...that dopamine-dependent encoding of reward-anticipatory Table 1 ...
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Interaction between the trace amine associated receptor 1 and the dopamine D2 receptor controls cocaine’s neurochemical actions
... amine-associated receptor 1 (TAAR1) plays a pivotal role in the regulation of dopamine (DA) transmission and cocaine’s ...2 receptor antagonist, L-741,626, rescued cocaine’s ability to produce ...
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Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure
... Retrograde ureteral infusion of AAV-9 vector provides efficient gene transfer in the kidney. The efficiency of renal gene transfer by AAV-9 following systemic administration was determined using an AAV vector encoding ...
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Comorbid Migraine with Aura, Anxiety, and Depression Is Associated with Dopamine D2 Receptor (DRD2) NcoI Alleles
... DRD2 NcoI allele frequencies were determined in The major finding of the present study is that the individuals based on the presence or absence of incidence of the clinical diagnoses of [r] ...
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Association between the traditional Chinese medicine pathological factors of opioid addiction and DRD2/ANKK1 TaqIA polymorphisms
... The dopamine D2 receptor (DRD2) was characterized previously with TaqIA, TaqIB, and TaqID SNPs based on restriction digestion of this region with the TaqI ...
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A Randomized, Prospective Comparative Study to Evaluate the Efficacy and Safety of Lurasidone and Risperidone in Treatment of Schizophrenia
... effects. Dopamine was one of the approximately 10 neurotransmitters distributed diffusely throughout the brain considered for pathophysiology of ...between dopamine function and schizophrenia came from ...
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<p>Once-Monthly Subcutaneously Administered Risperidone in the Treatment of Schizophrenia: Patient Considerations</p>
... Population pharmacokinetics and prediction of dopamine D2 receptor occupancy after multiple doses of RBP-7000, a new sustained-release formulation of risperidone, in schizophrenia patien[r] ...
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Thesis
... the dopamine D2 receptor (D2R), the primary target for antipsychotic drugs, to 17 human ...with D2- selective drug, quinpirole, and the D2R endogenous ligand, ...that dopamine and ...
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BIOCHEMICAL, NEUROCHEMICAL AND BEHAVIOURAL RESPONSES FOLLOWING ADMINISTRATION OF 6-FLUORO-3-(PIPERIDIN-4-YL) BENZO[D] ISOXAZOLE DERIVATIVES AND ANTIPSYCHOTIC DRUGS IN MICE
... with dopamine D2 receptor with lesser affinity and serotonin 5HT2a receptors with comparably higher affinity as possible drug molecules with fewer propensities to cause ...
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Disruption of Drug Effects (Dopamine, Nicotine, Pilocarpine, κ Opioid) in Planarians by UV Light
... by receptor-binding ...selective dopamine D2 receptor antagonist (–)sulpiride ...acetylcholine receptor agonist nicotine (1, 3, 5 mM) and the selective mus- carinic acetylcholine ...
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Effects of Ovariectomy and 17β Estradiol Replacement on Dopamine D2 Receptors in Female Rats: Consequences on Sucrose, Alcohol, Water Intakes and Body Weight
... of dopamine D2 receptors in the regula- tion of food intake and body ...that D2 receptor KO mice showed reduced food intake and body weight along with an increased basal energy expenditure ...
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Sensitivity to Dopamine D1/D2 Receptor Stimulation in Mice Lacking Connexin-32 or Connexin-36
... D1/D2 receptor interactions described above hold true under normal conditions, but the requisite D1/D2 synergism is broken down with prolonged DA depletion in the ...or D2 agonists become ...
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