dopamine receptors
Comparison of Effects of Light Anesthetics, Diethyl Ether and Carbon Dioxide, on Hypothalamic Paraventricular Nucleus D1 and D2 Dopamine Receptors- and Glucosensitive Neurons-Induced Food Intake in Fasted Conscious Rats
... 4 receptors in PVN may be a pharmacological tar- get for ...2 Dopamine Receptors (DR) and also Gluco sensitive Neurons (GSNs) in the hypothalamic Paraventricular Nucleus (PVN) increased food intake ...
6
Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis
... for dopamine receptors (DRs), is shown to induce the differentiation of cancer stem cells in leukemic disease and breast cancer, but it is not known if this drug would affect liver ...HCC, dopamine ...
10
Potential link between genetic polymorphisms of <em>catechol-O-methyltransferase </em>and dopamine receptors and treatment efficacy of risperidone on schizophrenia
... Methods: A total of 690 schizophrenic patients (case group) were selected and 430 healthy people were included as the controls. All patients received risperidone treatment continuously for 8 weeks. Next, peripheral ...
9
Structural basis for ligand-binding and activation of D1-like dopamine receptors
... anhydride, dopamine, IBMX, pargyline, propranolol, SKF38393, and triethyleneamine, and 2’-O-monosuccinyladenosine 3’:5’- monophosphate tyrosyl methyl ester (ScAMP-TME) were purchased from Sigma-Aldrich ...
201
Structure and function studies of the human dopamine receptors
... of dopamine to the ...of dopamine, the interaction with Asn316 fulfils the ability of the amino group to form favorable interactions with any other ...why dopamine exhibits reduced binding to the D 5 ...
118
Dopamine Stimulation of Active Na and Cl Absorption in Rabbit Ileum: INTERACTION WITH α2 ADRENERGIC AND SPECIFIC DOPAMINE RECEPTORS
... of dopamine on active intestinal ion transport have been ...technique. Dopamine, in the presence of 1 mM ascorbic acid, added to the serosal bathing solution caused a dose-dependent decrease in ...
10
Chemical Scale Studies of the 5 HT₃ and D2 Dopamine Receptors
... The ligand binding site of aminergic GPCRs is a crevice formed between the seven transmembrane helices (16, 17) (figure 3.2). Key elements of this site include a cluster of conserved aromatic residues and a highly ...
173
Transdermal iontophoresis of dopaminergic (pro) drugs : from formulation to in vivo application
... the dopamine receptors to reduce development of motor ...a dopamine agonist, bromocriptine, showed promising efficacy but has not been widely used in Parkinson’s disease ...other dopamine ...
232
Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat
... of dopamine receptors, impairs PPI [13]; and agents with the ability to reverse disruptive effect of apomorphine on PPI have been considered as potential antipsychotics ...
8
Adenosine A2 Receptor: Novel Target for the Management of Parkinsonism
... A2A receptors in basal ganglia that are richly innervated by dopamine, and their antagonistic role towards the stimulation of dopamine receptors, have positioned A2A receptor antagonists as an ...
5
Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non atrophying and atrophying conditions
... brain, dopamine controls a multitude of functions including locomotor activity, cognition, emotion, positive reinforcement, food intake and endo- crine ...periphery, dopamine modulates cardiovascular ...
8
In vitro pharmacological characterization of SPN-810M (molindone)
... 2L dopamine receptors and the serotonin receptor 5-HT 2B ; it is not as potent for the 5-HT 2A ...2L receptors, and that the parent drug, SPN-810M, and not the major human metabolites (P1-2 and ...
9
Original Article Dopamine receptor expression on primary osteoblasts and bone marrow mesenchymal stem cells of rats
... specific receptors. The structures of dopamine receptors of the same subfamily are similar; the transmembrane do- mains of D1R and D5R exhibit 80% ...[3]. Dopamine receptors have been ...
7
Formulation and Evaluation of Quetiapine Fumarate Sustained Release Tablets
... D2 receptors in the dopamine pathways of the brain. Dopamine released in these pathways has less ...of dopamine in the mesolimbic pathway has been linked to psychotic ...the dopamine ...
6
Interactions between striatal dopamine and adenosine receptors: effects of aminophylline on a pharmacological model of parkinson's disease
... The most common hypokinetic motor disorder of NB is Parkinson's disease, characterized by (1) muscle stiffness that is present in all muscle groups, both flexors and extensors, which is usually accompanied by sudden ...
11
Etiology, drugs and incidence in Cotard syndrome
... Several times antipsychotics benzodiazepines antagonists of dopamine receptors have been shown as effective alternative for treatment of patients with Cotard [15,31]. Among the most used atipical ...
7
Persistent defective coupling of dopamine 1 receptors to G proteins after solubilization from kidney proximal tubules of hypertensive rats
... hypertensive rat (SHR), partly because of defective DA-1 receptor-adenylate cyclase (AC) coupling in renal proximal convoluted tubules. To investigate this defective coupling, DA-1 dopamine receptors from ...
6
DOPAMINE RECEPTOR D3R AND D4R MRNA LEVELS IN PERIPHERAL LYMPHOCYTES IN PATIENTS WITH SCHIZOPHRENIA AND ITS CORRELATION WITH SEVERITY OF ILLNESS
... PBL dopamine receptors mRNA expression levels can operate as peripheral diagnostic markers for schizophrenia or for sub-typing of illness are highly ...
11
Hypotension and bradycardia, a serious adverse effect of piribedil, a case report and literature review
... of dopamine receptors (which include the D2, D3, D4 receptors), but the ergot DAs have a higher affinity for alpha-adrenergic (alpha-1 and alpha-2) and serotonergic (5-HT1 and 5-HT2) receptors ...
5
Dopamine D2 receptors in the pathophysiology of insulin resistance
... that dopamine receptors might be involved in the beneficial effect of calorie restriction on glucose ...that dopamine receptors are part of the mechanism underlying the beneficial effect of ...
168