Dorsal mesoderm
FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development
... the dorsal marginal zone by FoxD3MO ...in dorsal mesoderm ...non-dorsal mesoderm was inhibited throughout the marginal zone by VP16-FoxD3 ...for mesoderm formation in the ...
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EphA4 dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula
... (Fig. 10A,B). The lack of previous involution affects the axis. Chordin is normally expressed in anterior chordamesoderm, but not posteriorly in the lip. By contrast, in DN-Pak1 embryos expression extends into the lip, ...
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Ancestral mesodermal reorganization and evolution of the vertebrate head
... head mesoderm of vertebrates compared with amphioxus indicates that A/P re-arrangement of mesodermal gene expression occurred in the lineage of ...the dorsal mesoderm, such as bra and fgf8/17/18, ...
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Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function
... single dorsal blastomere at the 4-cell stage or a single dorsal vegetal blastomere at the 8-cell ...ectopic dorsal structures such as notochord are formed ...of dorsal mesoderm observed ...
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Negative regulation of Activin/Nodal signaling by SRF during Xenopus gastrulation
... on mesoderm formation as shown in our ...the mesoderm- and endoderm-inducing ...with dorsal mesoderm and endoderm at high concentrations and ventral mesoderm at low concentrations ...
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The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins
... XDSCR6 is a member of the RIPPLY family of proteins known to be involved in somite segmentation (Wardle and Papaioannou, 2008); however, whether it plays an early role in development is not clear. RT-PCR analyses ...
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Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila
... the mesoderm-ectoderm interface To explore the functional importance of the radial protrusions for mesoderm spreading, we sought to identify a way to interfere selectively with their ...of dorsal ...
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Post transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading
... subsequent mesoderm spreading over the ectoderm is abnormal (Nabel-Rosen et ...abnormal mesoderm spreading on later stages of mesoderm development, we analyzed the expression pattern of various ...
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Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation
... Overexpression of XPIASy in the DMZ suppresses dorsalization of embryos, which is similar to the inhibition of XSmad2 (Fig. 3A, parts f,g) and can be largely rescued by co- overexpression with XSmad2 (Fig. 3B, part b). ...
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Origin and evolution of endoderm and mesoderm
... of mesoderm inducers such as Activin or related TGF-ß molecules (Smith et ...to dorsal mesoderm (Smith et ...in mesoderm specification and axis elongation (Beddington et ...and mesoderm ...
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Regulation of TGF β signalling by N acetylgalactosaminyltransferase like 1
... of dorsal (DMZ) and ventral marginal zone (VMZ) explants at stage ...(ventral mesoderm), msx1 (neural crest, epidermis) was reduced in VMZ from embryos microinjected with 200 pg xGalntl-1 mRNA, whereas the ...
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A Failure of Induction in Normal Development
... We are left with the alternatives that the side-plate mesoderm is able to suppress the competence of the lateral ectoderm only while it is still in its place in the whole mesoderm field,[r] ...
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Decoupling of amniote gastrulation and streak formation reveals a morphogenetic unity in vertebrate mesoderm induction
... potent mesoderm inducers (Amaya et ...avian mesoderm formation has also been reported (Chuai et ...Induced mesoderm ring exhibits anamniote-like dorsoventral ...(C) Mesoderm dorsoventral ...
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Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm
... cranial mesoderm [9–12], although these find- ings have been controversial and difficult to ...cranial mesoderm of chick embryos [13, ...cranial mesoderm, a finding long regarded as reflecting ...
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Maternal zygotic medaka mutants for fgfr1 reveal its essential role in the migration of the axial mesoderm but not the lateral mesoderm
... The medaka fish (Oryzias latipes) is an emerging model organism for which a variety of unique developmental mutants have now been generated. Our recent mutagenesis screening of the medaka identified headfish (hdf), a ...
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Mesoderm migration in the Xenopus gastrula
... Int T Dev llinl ~O 305 311 (1996) 305 Mesoderm migration in the Xenopus gastrula RUDOLF WINKLBAUER*, MARTINA NAGEL, ANDREAS SELCHOW and STEPHAN WACKER Universitiit zu KOIn,Zoofogisches fnstitut, KOfn,[.] ...
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Bmp signaling maintains a mesoderm progenitor cell state in the mouse tailbud
... in mesoderm progenitor specification and maintenance (McMahon et ...T-positive mesoderm progenitor zone (Row and Kimelman, 2009), while transgenic expression of a dominant-negative version of the same ...
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The TAF10 containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo
... the mesoderm of T-Cre;Taf10 mutant embryos, we observed a difference in sensitivity to Taf10 loss between the LPM (and the intermediate mesoderm) and the paraxial ...the mesoderm and/or by cell death ...
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Epithelial mesenchymal transitions: the importance of changing cell state in development and disease
... Primary EMT Gastrulation Epiblast Axial mesoderm Embryonic notochord 105 EMT at the primitive streak Paraxial mesoderm somites Skeletal muscles, bones, tendons, satellite cells, compon[r] ...
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BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites
... the mesoderm except axial mesoderm (between ...recruited mesoderm expressing Lefty2 was observed at the middle and distal regions of the primitive streak (F ⬘ , red arrow ...
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