Double hit
Effect of Microalloying on Double hit Compression Behavior of AZ31 Alloy
... Abstract. Double-hit compression tests were performed on the AZ31 and ...second hit, the flow stress first decreased rapidly and then slowly to a certain ...
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Double-hit lymphomas: clinical, morphological, immunohistochemical and cytogenetic study in a series of Brazilian patients with high-grade non-Hodgkin lymphoma
... DHL: Double-hit lymphomas; DLBCL: Diffuse large B-cell lymphoma; Fish: Fluorescence in situ hybridization; GCB: B germinal centre; HE: Hematoxylin and eosin; LDH: Lactic dehydrogenase; MO: Bone marrow ...
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Establishment and characterization of a novel MYC/BCL2 “double-hit” diffuse large B cell lymphoma cell line, RC
... Background: Diffuse large B cell lymphoma (DLBCL) is the most common type of lymphoid malignancy worldwide. Approximately 5 % of cases of DLBCL are so-called double-hit lymphomas (DHL), defined by a ...
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Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma
... MYC/BCL2 double hit lymphoma (DHL) has been the subject of many studies; however, no study has systemically compared the clinicopathologic features and prognostic factors between patients with de novo ...
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Original Article Double-hit mantle cell lymphoma with MYC gene rearrangement or amplification: a report of four cases and review of the literature
... as double hit lymphoma, MCL with both CCND1 and MYC gene rearrangements is specified as double hit MCL ...as double hit MCL, even though the “second hit” by deregulated ...
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Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury
... Acute Respiratory Distress Syndrome (ARDS) is a life- threatening syndrome consisting of acute onset respiratory failure caused by noncardiogenic edema and characterized by hypoxemia and radiological bilateral lung ...
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Original Article A modified “double-hit” induced acute lung injury model in rats and protective effects of tetramethylpyrazine on the injury via Rho/ROCK pathway
... Then, we used histological examination to access “double-hit” induced lung injury in rats. In contrast to the control animals, LPS caused marked leukocyte infiltration, thickening of interalveolar membranes ...
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Case Report Double-hit and triple-hit lymphomas arising from follicular lymphoma following acquisition of MYC: report of two cases and literature review
... Abstract: Double-hit or triple-hit B-cell lymphomas (DHL and THL) are rare subtype lymphomas usually associated with poor prognosis. It is defined by two or three recurrent chromosome translocations; ...
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Rare double-hit with two translocations involving IGH both, with BCL2 and BCL3, in a monoclonal B-cell lymphoma/leukemia
... with lymphocytosis, and who was found to have a marked bone marrow involvement by neoplastic lymphocytes showing a B-cell line of differentiation as determined by flow cytometry and immunohistochemistry. Morphologic- ...
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Simultaneous targeting of XPO1 and BCL2 as an effective treatment strategy for double-hit lymphoma
... Double-hit lymphoma (DHL) is among the most aggressive and chemoresistant lymphoma subtypes. DHLs carry genomic abnormalities in MYC, BCL2, and/or BCL6 oncogenes. Due to the simultaneous overexpression of ...
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Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors
... single hit (MYC/IG; SH) seen in Raji and Ramos Burkitt lymphoma cell lines; MYC rearrange- ment with BCL2 gene (MYC/BCL2; DHL) seen in OCILY1, OCILY10, SUDHL2, and DOHH2 cell lines; or MYC rearrangements with both ...
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Prognostic impact of diffuse large B-cell lymphoma with extra copies of MYC, BCL2 and/or BCL6: comparison with double/triple hit lymphoma and double expressor lymphoma
... “ double-hit ” (DHL) or “ triple-hit ” lymphoma (THL) ...“ double- expressor ” lymphoma (DEL), which accounted for approximately 19 – 34% of cases of DLBCL ...
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Maximizing Precision of Hit Predictions in Baseball
... Ballpark Factor 3 , which approximates the advantage that a park gives to hit- ters, relative to other ballparks. A simple batting average over all of the at-bats in the park would not work, because that is highly ...
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Hit identification of IKKβ natural product inhibitor
... In conclusion, we have discovered a new small molecule IKKβ inhibitor from a large natural product library of 90,000 compounds using high-throughput structure- based molecular docking.. [r] ...
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Hit Miss Networks with Applications to Instance Selection
... In supervised learning, a training set consisting of labeled instances is used by a learning algo- rithm for generating a model (classifier) that is subsequently employed for deciding the class label of new instances ...
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Single Hit Energy-resolved Laue Diffraction
... Single Hit Energy-resolved Laue Diffraction (SHiELD) has been demonstrated as a technique for performing in- situ Laue x-ray diffraction with the additional advantage of being able to measure both unit cell volume ...
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Physical Evidence in Hit and Run Traffic Deaths
... In many hit-and-run cases there are no eyewitnesses and the victim is past talking, so physical tidence becomes all important, and the solution fthe crime depends on the recognition, pro[r] ...
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Argatroban for an alternative anticoagulant in HIT during ECMO
... of HIT linked to cardiac surgery ...of HIT during cardiac surgery, but carries a risk of renal failure and anaphylactic shock [15] and is no more ...of HIT treatment with fon- daparinux has also been ...
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Automating the composition of popular music : the search for a hit
... University of Huddersfield Repository Millea, Timothy A and Wakefield, Jonathan P Automating the composition of popular music the search for a hit Original Citation Millea, Timothy A and Wakefield, Jo[.] ...
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Simulation and Optimization of the Performance in Hit Solar Cell
... The doping concentration and the thickness of different layers in the Hetero-junction with Intrinsic Thin layers solar cells (HIT) strongly influence their performances. We simulated, using AFORS-HET simulation ...
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