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Double Primary

Unusual synchronous double primary treatment naïve lung adenocarcinoma harboring T790M and L858R mutations in early stage lung cancer

Unusual synchronous double primary treatment naïve lung adenocarcinoma harboring T790M and L858R mutations in early stage lung cancer

... multiple primary lung cancer, and compli- cated mutations (L858R/S768I, L858R/20ins, G719X/ T790M, 19del/T790M, 19del/L858R, and 19del/20ins) have only been found in female patients ...synchronous double ...

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Synchronous double primary hepatic cancer consisting of hepatocellular carcinoma and cholangiolocellular carcinoma: a case report

Synchronous double primary hepatic cancer consisting of hepatocellular carcinoma and cholangiolocellular carcinoma: a case report

... Synchronous double primary hepatic cancer consisting of HCC and intrahepatic cholangiocarcinoma (ICC) is also rarely encountered in clinical ...of primary liver cancers [4]. Only five cases of ...

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Double primary bronchogenic carcinoma of the lung and papillary thyroid carcinoma: a case report

Double primary bronchogenic carcinoma of the lung and papillary thyroid carcinoma: a case report

... He was later readmitted and underwent a left thyroid lobectomy for what appeared to be a nodular goiter. Microscopy revealed a papillary structure with a ground- glass appearance of tumor cell nuclei. Some colloid within ...

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Original Article Possible prognostic significance of p53, cyclin D1 and Ki-67 in the second primary malignancy of patients with double primary malignancies

Original Article Possible prognostic significance of p53, cyclin D1 and Ki-67 in the second primary malignancy of patients with double primary malignancies

... of primary cancers are ...second primary malignancy. Tissue samples were obtained from the second primary cancer site of 43 patients who met the diagnostic criteria for double primary ...

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Case Report Synchronous double primary gastric and endometrial cancer: a case report and literature review

Case Report Synchronous double primary gastric and endometrial cancer: a case report and literature review

... Multiple primary malignant neoplasms (MPMN) are two or more malignancies in an individual without any relationship between the ...Synchronous double primary gastric and endometrial cancer are ...

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Synchronous double primary squamous cell carcinoma and adenocarcinoma of the extrahepatic bile duct: a case report

Synchronous double primary squamous cell carcinoma and adenocarcinoma of the extrahepatic bile duct: a case report

... with double cholan- giocarcinomas are exceptionally ...indeed double primary cancers were ...of double primary cancers ...of double adenocarcinomas of the ...were double ...

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Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer

Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer

... second primary cancer of thyroid on the survival of BC ...second primary cancer. BC patients with metachronous and synchronous double primary TC showed similar ...

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High Grade Extremity Myxofibrosarcoma with Synchronous Mesenteric Leiomyosarcoma: Double Primary Sarcomas

High Grade Extremity Myxofibrosarcoma with Synchronous Mesenteric Leiomyosarcoma: Double Primary Sarcomas

... coexistent primary tumor, thus preclud- ing its ...multiple primary tumors should always be taken into consideration in the differen- tial diagnosis when synchronous sarcomas are encoun- ...

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Targeted sequencing identifies the mutational signature of double primary and metastatic malignancies: a case report

Targeted sequencing identifies the mutational signature of double primary and metastatic malignancies: a case report

... gold standard, is used in the routine assessment of tumor samples for diagnostic purpose. However, in some cases, as in our patient, IHC was only suggestive of the diagnosis and did not provide a conclusive origin of the ...

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Double Synchronous Primary Gynecologic Carcinoma of the Endometrium and Both Ovaries: A Rare Encounter

Double Synchronous Primary Gynecologic Carcinoma of the Endometrium and Both Ovaries: A Rare Encounter

... synchronous primary endometrial and ovarian cancer reported lymphovascular space invasion (LVSI), non- endometrioid type ovarian cancer and stage of ovarian cancer above stage I were independent prognostic factors ...

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Synchronous double cancers of primary hepatocellular carcinoma and cholangiolocellular carcinoma: a case report

Synchronous double cancers of primary hepatocellular carcinoma and cholangiolocellular carcinoma: a case report

... Synchronous double cancers consisting of hepatocellular carcinoma (HCC) and cholangiolocellular carcinoma (CoCC) are extremely ...synchronous double cancers in a patient with primary HCC and ...

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Effect of Triflusal on Primary Vascular Dysregulation Compared with Aspirin: A Double Blind, Randomized, Crossover Trial

Effect of Triflusal on Primary Vascular Dysregulation Compared with Aspirin: A Double Blind, Randomized, Crossover Trial

... This study proceeded in a double-blind, randomized, cross- over design. Fig. 1 describes the overall process of the study. In short, the selected patients were given either triflusal (300 mg, b.i.d.) or aspirin ...

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... With prevalence rates of many allergic diseases increas- ing, new methods for the primary prevention of these condi- tions represent an exciting prospect. While some promising evidence has emerged supporting the ...

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Innovative Design and Analysis of Support Arrangement for Double  Walled Tank Containing Primary Sodium

Innovative Design and Analysis of Support Arrangement for Double Walled Tank Containing Primary Sodium

... To meet the above features, a conical support shell is designed to support the priming tank. The conical support shell is attached to the priming tank through a ring. The double envelope is also attached to the ...

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Original Article Double immunohistochemical staining with laminin 5 (γ2 chain) and collagen IV in colorectal neoplasms

Original Article Double immunohistochemical staining with laminin 5 (γ2 chain) and collagen IV in colorectal neoplasms

... a double immunohistochemical staining for laminin 5 (γ2) and collagen IV in different colorectal ...the primary histopathological diagnoses of tubular adenoma, tubulovillous adenoma, adenoma with ...

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Primary Immunization of Infants With an Acellular Pertussis Vaccine in a Double-Blind Randomized Clinical Trial

Primary Immunization of Infants With an Acellular Pertussis Vaccine in a Double-Blind Randomized Clinical Trial

... of adverse reactions to acellular vaccine, whole-cell vaccine, and placebo injections; (2) to evaluate the antibody response to acellular vaccine as compared to a plain whole-cell vaccin[r] ...

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Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

... Biospecimen collection and analysis. Tumor specimens before and after treatment were obtained at the time of diagnostic evaluation and definitive resection. A representative portion of each tumor (the equivalent of at ...

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DEVELOPMENT OF NOVEL SYNTHETIC METHODOLOGIES AND ITS APPLICATION TOWARDS THE TOTAL SYNTHESIS OF SCYTOPHYCIN-C

DEVELOPMENT OF NOVEL SYNTHETIC METHODOLOGIES AND ITS APPLICATION TOWARDS THE TOTAL SYNTHESIS OF SCYTOPHYCIN-C

... The benzyl group of 20 is selectively deprotected using Li and Naphthalene in THF to afford primary alcohol 21 without disturbing the double bonds in the dihydro[r] ...

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A study of sertraline in dialysis (ASSertID): a protocol for a pilot randomised controlled trial of drug treatment for depression in patients undergoing haemodialysis

A study of sertraline in dialysis (ASSertID): a protocol for a pilot randomised controlled trial of drug treatment for depression in patients undergoing haemodialysis

... Demographic and clinical data will be collected at screening interview, baseline interview and 2 weeks, and every month (up to 6 months) after baseline. The primary outcome is to evaluate the feasibility of ...

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A randomized, double blind, placebo controlled phase III trial of duloxetine in Japanese fibromyalgia patients

A randomized, double blind, placebo controlled phase III trial of duloxetine in Japanese fibromyalgia patients

... The primary efficacy measure was analyzed using a mixed- effects model repeated-measures (MMRM) approach to compare the change from baseline in BPI average pain score at week 14 of study treatment between the ...

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