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Drosophila CNS

Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers

Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers

... of Drosophila CNS midline cell development has been transcriptional ...Berkeley Drosophila Genome Project (BDGP) gene expression database has embryonic in situ hybridization (ISH) data on 7559 genes, ...

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Regulation of synaptic connectivity: levels of fasciclin II influence synaptic growth in the Drosophila CNS

Regulation of synaptic connectivity: levels of fasciclin II influence synaptic growth in the Drosophila CNS

... the CNS (Schuster et ...adult CNS in Drosophila and is, therefore, ideally placed to contribute to central synapse development (Grenningloh et ...the Drosophila CNS (Baines and Bate, ...

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Multiple Notch signaling events control Drosophila CNS
midline neurogenesis, gliogenesis and neuronal identity

Multiple Notch signaling events control Drosophila CNS midline neurogenesis, gliogenesis and neuronal identity

... the Drosophila CNS provide a useful system for the comprehensive study of neurogenesis and ...embryonic CNS midline cells consist of a functionally diverse group of ~22 cells, including midline glia ...

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A genetic cascade involving klumpfuss, nab and castor specifies the abdominal leucokinergic neurons in the Drosophila CNS

A genetic cascade involving klumpfuss, nab and castor specifies the abdominal leucokinergic neurons in the Drosophila CNS

... the CNS of first instar larvae by immunostaining with an anti-Lk antibody: anterior LK (ALK), lateral-horn LK (LHLK), subesophageal LK (SELK) or abdominal LK (ABLK) ...

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Dendritic refinement of an identified neuron in the Drosophila CNS is regulated by neuronal activity and Wnt signaling

Dendritic refinement of an identified neuron in the Drosophila CNS is regulated by neuronal activity and Wnt signaling

... Fig. 7. Model summarizing the data on the regulation of dendritic refinement in Drosophila. (A) After pruning of larval branches, the adult dendrites undergo growth. (B) The innervation of aristal sensory neurons ...

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How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS

How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS

... promotes CNS longitudinal axon growth in two very different ways, constructing a pathway using its canonical signaling mechanism and promoting motility via the Notch/Abl ...

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Postsynaptic protein kinase a reduces neuronal excitability in response to increased synaptic excitation in the Drosophila CNS

Postsynaptic protein kinase a reduces neuronal excitability in response to increased synaptic excitation in the Drosophila CNS

... A diverse range of voltage- and ligand-gated ion channels is known to be modulated by cAMP/PKA phosphorylation (Levi- tan, 1999; Catterall, 2000). In addition to neuronal Na ⫹ chan- nels, one notable example is the ...

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β Spectrin functions independently of Ankyrin to regulate the
establishment and maintenance of axon connections in the Drosophila
embryonic CNS

β Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS

... the Drosophila CNS, we identified three ␤ -spectrin ...to CNS axons, suggesting that ␣ - Spectrin normally limits axonal accumulation of ␤ ...

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Programmed cell death in the embryonic central nervous system of
Drosophila melanogaster

Programmed cell death in the embryonic central nervous system of Drosophila melanogaster

... Although programmed cell death (PCD) plays a crucial role throughout Drosophila CNS development, its pattern and incidence remain largely uninvestigated. We provide here a detailed analysis of the ...

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Slit and Robo control the development of dendrites in Drosophila
CNS

Slit and Robo control the development of dendrites in Drosophila CNS

... embryonic Drosophila CNS have shown a role for Robo in directing growth cones away from the Slit-secreting ...in Drosophila embryos (Kramer et ...

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Fine tuning of secondary arbor development: the effects of the ecdysone
receptor on the adult neuronal lineages of the Drosophila thoracic
CNS

Fine tuning of secondary arbor development: the effects of the ecdysone receptor on the adult neuronal lineages of the Drosophila thoracic CNS

... the Drosophila adult lineages through expression of EcR-DN impact the functionality of the nervous system? Reduced or compacted secondary arbors could result in either absent, decreased or misaligned connections ...

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Drosophila Neurexin IV stabilizes neuron glia interactions at
the CNS midline by binding to Wrapper

Drosophila Neurexin IV stabilizes neuron glia interactions at the CNS midline by binding to Wrapper

... The small size of the differentially spliced Neurexin IV exons precluded in situ hybridization to determine their expression patterns. To test which of the two Neurexin IV mRNA isoforms is expressed in CNS ...

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CNS inflammation and neurodegeneration

CNS inflammation and neurodegeneration

... the CNS, including Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s disease, and the prototypic neuroinflammatory disease multiple sclerosis ...suppress CNS immune mechanisms, while others ...

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Interleukin 18 in the CNS

Interleukin 18 in the CNS

... In the CNS, Northern blot analysis failed to detect the presence of IL-Ra [64] and IL-Rb [65] soon after their cloning. The first evidence that IL-18R compo- nents are expressed in brain tissue was obtained by ...

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CNS resident classical DCs play a critical role in CNS autoimmune disease

CNS resident classical DCs play a critical role in CNS autoimmune disease

... the CNS during EAE and that their depletion or inactivation ame- liorates clinical disability ...murine CNS under physiological conditions are FLT3 dependent, differentiate from transferred pre-DCs, and ...

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CNS-2.ppt

CNS-2.ppt

...  shift rows (permute bytes between groups/columns) shift rows (permute bytes between groups/columns)  mix columns (subs using matrix multipy of groups) mix columns (subs using matri[r] ...

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Initiation and Regulation of CNS Autoimmunity: Balancing Immune Surveillance and Inflammation in the CNS

Initiation and Regulation of CNS Autoimmunity: Balancing Immune Surveillance and Inflammation in the CNS

... the CNS from the blood after this initial phase that are required for disease progression ...the CNS expression profiles of various co-stimulatory signals required for T cell activa- tion during the ...

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CNS-AU.pptx

CNS-AU.pptx

... • MSG4:B response involves decrementing the nonce and new challenge to A, both encrypted using a session key.. • MSG5: A response to B by decrementing the nonce encrypted using a sessio[r] ...

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Drosophila astrocytes cover specific territories of the CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch

Drosophila astrocytes cover specific territories of the CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch

... Remarkably, we found that Prospero is a key effector of the astrogenic effect of Notch. Prospero expression is selectively maintained in newly born and mature astrocytes. Prospero is required for the differentiation of ...

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Dual role for Drosophila lethal of scute in CNS midline precursor formation and dopaminergic neuron and motoneuron cell fate

Dual role for Drosophila lethal of scute in CNS midline precursor formation and dopaminergic neuron and motoneuron cell fate

... Embryo collection, in situ hybridization, immunostaining and confocal imaging were performed as previously described (Kearney et al., 2004; Wheeler et al., 2006; Wheeler et al., 2008). Digoxygenin-labeled or biotin- ...

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