Drosophila wing imaginal disc
Essential basal cytonemes take up Hedgehog in the Drosophila wing imaginal disc
... the Drosophila wing disc, Hedgehog (Hh) produced by posterior compartment cells distributes in a concentration gradient to adjacent cells of the anterior ...the wing disc, Hh ...
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Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc
... Insulin signaling regulates animal size in response to nutrition, and bovine insulin has been widely used to stimulate growth of explanted discs (Zartman et al., 2013; Handke et al., 2014; Mao et al., 2011, 2013; Legoff ...
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Patterning of wound-induced intercellular Ca2+ flashes in a developing epithelium
... Computational simulations allow us to decouple effects of cell size and anisotropy on intercellular Ca 2+ signaling dynamics. To analyze the potential roles of cell size and cell anisotropy as a driving force of these ...
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Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc
... A few genetic screens have been carried out in imaginal discs to identify regeneration genes. First, a screen of lacZ- containing P-element insertion lines, using a temperature- sensitive cell-lethal mutation to ...
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The control of morphogenesis in 'Drosophila' imaginal disc cell lines 'in vitro'
... Genetic analyses, which employ the use of viable mutations that only manifest themselves in the adult stages of development, strongly suggest that the PS integrins function in maintaining tension transmitting junctions ...
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Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc
... the wing pouch leads to ectopic induction of brk, loss in more central cells does not, suggesting that the relative contribution of Sax to overall Bmp signaling is less in the central cells where Tkv must ...
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Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization
... the wing imaginal disc, to follow the consequences of uniform PVR ...wild-type disc in A with ...contained wing imaginal discs that were approximately five times larger than ...
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Integrating force sensing and signaling pathways in a model for the regulation of wing imaginal disc size
... The wing imaginal disc of Drosophila serves as a widely used model system to study this ...the disc during growth. Growth stops once compression levels in the disc center reach a ...
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Notch signalling coordinates tissue growth and wing fate specification in Drosophila
... developing wing imaginal disc, expression of the homeodomain protein Homothorax (Hth) and the zinc-finger transcription factor Teashirt (Tsh) was restricted to the presumptive body wall, while the ...
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Activation and repression activities of ash2 in Drosophila wing imaginal discs
... in wing imaginal discs is the response to gradients of the morphogen ...the wing imaginal disc (Podos and Ferguson, 1999; Strigini and Cohen, ...in wing development, such as kni ...
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SoxF is part of a novel negative feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc
... Wild-type wing imaginal disc of a late L3 Drosophila larva counterstained with the actin marker rhodamine-phalloidin (B is a cross-section of the disc shown in ...the wing pouch ...
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Differential roles of the Drosophila EMT-inducing transcription factors Snail and Serpent in driving primary tumour growth.
... two Drosophila transcription factors, the classic EMT inducer Snail and the Drosophila orthologue of hGATAs4/6, Serpent, which drives an alternative mechanism of EMT; both Snail and GATA are specifically ...
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Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration
... larval imaginal discs of the genetically tractable model organism Drosophila melanogaster have complex patterning, well- characterized development and a high regenerative capacity, and are thus an excellent ...
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jing Is Required for Wing Development and to Establish the Proximo-Distal Axis of the Leg in Drosophila melanogaster
... an imaginal disc cDNA library con- structed in lgt10 using a fragment of genomic DNA adjacent to the P-element insertion site as ...the imaginal disc library correspond to this larger 7-kb ...
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Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration
... This model contrasts with a model arising from previous work demonstrating that NOS activity in the PG of post- feeding larvae inhibits the nuclear hormone receptor E75, an antagonist of ecdysone biosynthesis (Cáceres et ...
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DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis
... the wing differentiation regulators nubbin (Nub) and scalloped (Sd) ...as wing discs develop- ment progresses, which has indeed been observed for Atf3 expression ...
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TIE DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster
... a disc with seven or eight colors increases, and the likelihood of generating a disc with only three or four colors significantly decreases ...the wing imaginal disc was low; we ...
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Origin and proliferation of blastema cells during regeneration of Drosophila wing imaginal discs
... in Drosophila imaginal discs as a model with which to analyze the relationships between growth and pattern formation during ...3/4 wing disc fragments, examined the distribution of S-phase, ...
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Actin capping protein α maintains vestigial expressing cells within the Drosophila wing disc epithelium
... Drosophila imaginal discs are bilayered epithelial tissues consisting of a columnar monolayer epithelium covered by a squamous peripodial ...In Drosophila, two complexes important for polarity are ...
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Localised JAK/STAT Pathway Activation Is Required for Drosophila Wing Hinge Development
... dipteran wing hinge, a complex structure that is derived from an apparently simple region of the wing imaginal ...of wing hinge ...the wing imaginal disc is required for ...
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