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Drug-Induced

Role of hepatic transport proteins in drug disposition and drug-induced liver injury

Role of hepatic transport proteins in drug disposition and drug-induced liver injury

... Hepatic transport proteins may provide a protective role against drug-induced hepatotoxicity through changes in transporter expression (Ananthanarayanan et al., 1994). Intrahepatic and obstructive ...

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Drug-induced impairment of renal function

Drug-induced impairment of renal function

... of drug nephrotoxicity is increased in the patient with AKI or chronic kidney disease ...toxic drug effects on the ...for drug-induced renal impairment because cirrhotic patients tend to have ...

12

Drug-induced parkinsonism: diagnosis and management

Drug-induced parkinsonism: diagnosis and management

... Abstract: Drug-induced parkinsonism (DIP) has been known for >60 ...upon drug withdrawal in most ...a drug-free interval of at least 6 months is generally ...ing drug withdrawal or ...

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Drug-induced psoriasis: clinical perspectives

Drug-induced psoriasis: clinical perspectives

... This narrative review is based on a nonsystematic literature search in Medline and Embase databases. The search date was performed in January 2017 with an update of the search in June 2017. The following keywords were ...

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The 6R’s of drug induced nephrotoxicity

The 6R’s of drug induced nephrotoxicity

... approach drug induced nephrotoxicity focused on Risk assessment, early Recogni- tion, targeted Response, timely Renal support and Re- habilitation coupled with Research (the 6R ...

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CLINICAL UPDATES ON DRUG – INDUCED CARDIOTOXICITY

CLINICAL UPDATES ON DRUG – INDUCED CARDIOTOXICITY

... the drug-induced cardiotoxicity but the exact molecular involvement of toxicity is not much ...one drug approved for doxorubicin-related cardiotoxicity ...

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Drug-induced uveitis

Drug-induced uveitis

... of drug-induced uveitis. The mechanism(s) underlying drug-induced uveitis are generally unclear, al- though both inflammatory and toxic reactions have been suggested to play a role ...of ...

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Review Article Drug-induced megaloblastic, aplastic, and hemolytic anemias: current concepts of pathophysiology and treatment

Review Article Drug-induced megaloblastic, aplastic, and hemolytic anemias: current concepts of pathophysiology and treatment

... In drug-induced aplastic ane- mia, multipotent hematopoietic stem cells undergo damage before their differentiation to committed stem cells ...of drug-induced aplastic anemia is 2/million in ...

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Is the drug induced hypersensitivity syndrome (DIHS) due to human herpesvirus 6 infection or to allergy mediated viral reactivation? Report of a case and literature review

Is the drug induced hypersensitivity syndrome (DIHS) due to human herpesvirus 6 infection or to allergy mediated viral reactivation? Report of a case and literature review

... namely Drug-Induced Hypersensitivity Syndrome (DIHS), also called drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, anticonvulsant hypersensitivity syndrome (AHS), or ...

5

DRUG INDUCED HEMATOLOGICAL DISORDERS- A REVIEW

DRUG INDUCED HEMATOLOGICAL DISORDERS- A REVIEW

... a drug can cause more than one adverse ...adverse drug reaction of a drug. Some of the drug-induced syndromes include aplastic anaemia, ...

8

Drug induced muscle disorders

Drug induced muscle disorders

... Drug induced musculoskeletal disorders can potentially affect the spectrum of anatomical structures including bone, connective tissue and the ...cause drug induced disorders ranging from ...

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Drug induced gingival enlargement

Drug induced gingival enlargement

... of drug-induced gingival enlargement ...administered drug and clinical characteristics and it can include non-surgical treatments, surgical treatments as drug replacement ...

8

Drug Induced Parkinsonism: A Causality, Severity, and Preventability Assessment study in a Tertiary Care Hospital

Drug Induced Parkinsonism: A Causality, Severity, and Preventability Assessment study in a Tertiary Care Hospital

... DIP is often misdiagnosed as Parkinson’s disease, hence exact incidence and prevalence are not clearly known. Chlorpromazine (CPZ) was the first antipsychotic drug to be studied for extapyramidal side effects, ...

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Management of Drug Induced Gingival Overgrowth

Management of Drug Induced Gingival Overgrowth

... A 43 years old female patient reported to Department of Dental surgery with a chief complaint of swollen gums and bleeding on brushing from last 2 weeks. On elaborating the history of presenting illness she noticed ...

5

Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches

Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches

... HRCT is currently the best non-invasive method to as- sess the presence of drug-induced lung disease. The results of HRCT in DILD are similar to those of ILDs from other causes or those of idiopathic ...

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Drug-Induced Fatty Liver

Drug-Induced Fatty Liver

... damage induced by chemotherapy in patients undergoing neoadjuvant chemotherapy for colorectal liver metastasis, and the results showed that steatosis is a common histological finding, with different possible ...

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Drug induced erythrocyte membrane internalization

Drug induced erythrocyte membrane internalization

... Nevertheless, differences between vacuole formation in whole red blood cells and ghosts are indicated by the lack of inhibition of ghost membrane internalization by PHMPS Table V and the[r] ...

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Evolution of Fluconazole Resistant Candida albicans Strains by Drug Induced Mating Competence and Parasexual Recombination

Evolution of Fluconazole Resistant Candida albicans Strains by Drug Induced Mating Competence and Parasexual Recombination

... acquired drug resistance mutations during treatment with the commonly used antifungal agent fluconazole rapidly develop further increased resistance by genome rearrangements that result in simultaneous loss of ...

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Severe DRESS Syndrome Managed With Therapeutic Plasma Exchange

Severe DRESS Syndrome Managed With Therapeutic Plasma Exchange

... Y. Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among her- pesviruses and antiviral and antidrug im- mune ...

7

Characterisation of molecular mechanisms involved in nevirapine- induced hypersensitivity

Characterisation of molecular mechanisms involved in nevirapine- induced hypersensitivity

... In order to assess the specificity of the elevated miR-205 levels for mild and/or severe skin reactions, additional work is needed to confirm if miR-205 is a specific marker of drug-induced cADRs. ...

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