dry powder inhalation
Formula Optimization of Rifampicin Dry Powder Inhalation with Chitosan-Xanthan Carrier Using Response Surface Methodology
... This study was aimed to obtain an optimum formula of rifampicin dry powder inhalation (DPI) with chitosan-xanthan (CX) as a carrier by spray drying method using response surface methodology (RSM). ...
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Simultaneous Estimation of Formoterol Fumarate Dihydrate and Fluticasone Propionate in Dry Powder Inhalation Formulation by HPTLC
... Literature survey revealed that various analytical methods such as spectrophotometry [5-9], HPLC[10-18], HPTLC [19] and NMR [20]have been reported for determination of Formoterol fumarate dihydrate (FFD) and Fluticasone ...
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FORMULATION AND EVALUATION OF ENGINEERED PHARMACEUTICAL FINE PARTICLES OF BUDESONIDE FOR DRY POWDER INHALATION (DPI) PRODUCED BY AMPHIPHILIC CRYSTALLIZATION TECHNIQUE: OPTIMIZATION OF PROCESS PARAMETERS
... for Dry Powder Inhalation, produced by environmentally driven Amphiphilic crystallization technique process by using different nonionic surfactants at different concentration and at different ...
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Development of a microparticle-based dry powder inhalation formulation of ciprofloxacin hydrochloride applying the quality by design approach
... classification, dry powder inhalation formulation tests were successfully performed in ...The dry powder formulations prepared were examined by particle size analysis, scanning electron ...
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Knowledge and practice of dry powder inhalation among patients with chronic obstructive pulmonary disease in a regional hospital, Nepal
... a dry powder inhaler device, and a purposive sampling technique was ...about dry powder inhaler (DPI) and inhalation while a Dutch Asthma Foundation observation checklist for rotahaler ...
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Development of chitosan-based dry powder inhalation system of cisplatin for lung cancer
... In the present study, in vitro inhalation performance of microspheres was evaluated using twin stage glass impinger. Chitosan microspheres, when formulated as DPI formulation without using any carrier particles, ...
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Assessment of satisfaction with different dry powder inhalation devices in Greek patients with COPD and asthma: the ANASA study
... During the first visit (day 0), patients were informed about the study and a written consent was obtained. Demographics and medical history were obtained and patients were cat- egorized in one of the three available ...
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Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols
... as dry powder inhalations (DPIs) via spray drying and jet milling under various parameters, to comprehensively characterize the physicochemical properties of the BST hydrate microparticles, and to evaluate ...
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Development of a novel dry powder inhalation formulation for the delivery of rivastigmine hydrogen tartrate
... Outlet temperature, yield of spray dried powders, RHT loading, geometric particle size, bulk and tapped density, residual solvent content, glass transition and aerodynamic characteristic[r] ...
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Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage
... of dry powder inhalation (DPI) ...microparticles. Powder X-ray diffraction (PXRD) studies revealed that the RIF API (active pharmaceutical ingredient) exists as molecular dispersion in ...
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Effectiveness and tolerability of formoterol plus glycopyrronium combination in patients with chronic obstructive pulmonary disease: FINE registry
... Methods: This was an open-label, observational registry in which COPD patients, who were prescribed forglyn (a brand of FDC of glycopyrronium 25 mcg and formoterol fumarate dihydrate 6 mcg dry powder ...
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DEVELOPMENT AND VALIDATION OF ULTRA PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR THE ANALYSIS OF PULMONARY DRUG PRODUCT CONTAINING FORMOTEROL FUMARATE AND FLUTICASONE PROPIONATE
... The study was undertaken to develop and validate a simple, sensitive and rapid analytical UPLC method for simultaneous estimation of Formoterol fumarate and Fluticasone propionate in dry powder ...
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Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis
... new dry powder formulations of colistimethate sodium (Colobreathe; Forest Laboratories, Dartford, UK) and tobramycin (TOBI Podhaler; Novartis Pharmaceuticals, Camberley, UK) have become available, delivered ...
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Particle engineering of materials for oral inhalation by dry powder inhalers I Particles of sugar excipients (trehalose and raffinose) for protein delivery
... of powder collected from the device, capsule and impactor was calculated, and the analysis was accepted if this fell within 75% - 125% of the nominal loaded dose (USP, ...
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ADVANCEMENTS IN DRY POWDER INHALER
... These are spray dried, small, porous particles containing phospholipids. The drug is dissolved in a solvent and then precipitated to produce fine particles [25,26]. This technique allows for greater control of particle ...
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Interim Best Practices for Working with Nanoparticles
... At this time, relatively little is known about the potential toxicity of nanoparticles, especially engineered nanoparticles. Recent toxicology studies, however, suggest possible adverse health effects associated with ...
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Pulmonary Hypersensitivity Associated With Pancreatin Powder Exposure
... induced by casual, repeated inhalation of pancreatin powder (desiccated pork pancreas) is described.. The powder was being employed as a dietary supplement for the patient’s son,.[r] ...
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Colistimethate sodium for the treatment of chronic pulmonary infection in cystic fibrosis: an evidence-based review of its place in therapy
... sodium inhalation treatment, a 2-week intravenous treatment with tobramycin plus β -lactam antibiotics was ...of inhalation colistin treatment as an adjunct to regular intravenous therapy has been proposed ...
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The Development of A New Dry Powder Inhaler
... formulation, powder processing and ...in powder preparation would not affect the aerosol performance, but charge produced in powder filling and packaging would affect its ...mannitol powder ...
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Evaluating inhaler use technique in COPD patients
... 200 inhalation demonstrations from the 103 patients were used for the analysis per ...of inhalation) revealed significant differences in incorrect inhalation techniques between the devices, as ...
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