DU 145 cells
Size-dependent cellular toxicity and uptake of commercial colloidal gold nanoparticles in DU-145 cells
... of DU-145 ...with DU-145 ...in cells and mediate biological processes (Jiang et ...the DU-145 cells and hence, this mechanism can be further developed to ...
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Anthocyanin Induces Apoptosis of DU 145 Cells In Vitro and Inhibits Xenograft Growth of Prostate Cancer
... The experimental animals were 6-week-old male BALB/c nude mice, weighing 18‒22 g, provided by Samtaco Bio Co. (Osan, Korea). After a 1-week adjustment period, the animals were maintained in plastic cages, with 5 animals ...
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<p>S100A9 promotes prostate cancer cell invasion by activating TLR4/NF-κB/integrin β1/FAK signaling</p>
... and DU-145 cells was determined by quantitative real-time polymerase chain reaction (PCR) (qRT-PCR) and Western ...The DU-145 cells metastasis in vivo was determined in mice ...
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Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles
... Adenocarcinoma cells were pur- chased from Sigma-Aldrich (Castle Hill, NSW, ...Australia). DU-145 cells originated from the American Type Culture Collection (Manassas, VA, USA) and were a ...
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DU-145 prostate carcinoma cells that selectively transmigrate narrow obstacles express elevated levels of Cx43
... transmigrating cells. Thus, a fraction of DU-145 cells can preferentially transmigrate narrow obstacles in the presence of non-functional ...of DU-145 cell transmigration ...of ...
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Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis
... melanoma cells to TRAIL-induced apoptosis ...LNCaP, DU 145, PC3 cells) and that TRAIL-induced cell death is only linked to the DR5 receptor, moreover they found DcR1 receptor expres- sion to ...
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CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling
... and DU-145 cells being pre-treated with 0, 20, 40, or 80 μM CAPE for 24 h was determined by MWA with 264 different antibodies detecting important signaling proteins (Figure 2A, ...PC-3 cells, ...
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Anti tumor and anti angiogenic effects of Fucoidan on prostate cancer: possible JAK STAT3 pathway
... Methods: DU-145 human prostate cancer cells were treated with 100 – 1000 μ g/mL of ...with DU-145 cells to induce xenograft model, and treated by oral gavage with 20 mg/kg of ...
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Handling Inconsistency in Knowledge Bases
... of cells in ...of cells in S phase compared to ...of cells in the G2 ...cancer cells and xanthorrhizol induces G1 and G2/M arrests in human colon cancer cells ...asynchronized ...
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Nobiletin suppresses cell viability through AKT Pathways in PC-3 and DU-145 prostate cancer cells
... treatment, with a greater inhibition in PC-3 cells. Fur- thermore, it was found that nobiletin inhibited VEGF expression through regulating AKT/HIF-1α pathways in prostate cancer cell line PC-3. Increasing HIF-1α ...
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Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites
... It is possible that UCHL1 has a role in regulating gene expression through changes in the stabilization of shelterin proteins. As several shelterin proteins (TRF1, TRF2, POT1 and RAP1) are ubiquitinated, UCHL1 may have a ...
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Incorporation of a selective sigma-2 receptor ligand enhances uptake of liposomes by multiple cancer cells
... tumor cells, we investigated the utility of the SV119 liposomes for the targeted delivery of anticancer ...The DU-145 cells were pre-treated with DOX-loaded SV119 liposomes (SV119-L[D]), ...
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NIR-Cyanine Dye Linker: a Promising Candidate for Isochronic Fluorescence Imaging in Molecular Cancer Diagnostics and Therapy Monitoring
... This observation also applied for the blue signal in- tensity. The fluorescence intensity of the green fluo- rescence signal derived from the WGA staining of the cell membranes was increased and remained nearly ...
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<p>LncRNA LINC00665 Promotes Prostate Cancer Progression via miR-1224-5p/SND1 Axis</p>
... Figure 4 LINC00665 was a sponge for miR-1224-5p. (A) Luciferase reporter assay was performed using LINC00665 reporter and the ten most potential target miRNAs. (B) Diagram of the putative binding site in LINC00665 with ...
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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells
... 4°C. Cells were then washed once in PBS containing 5 mM EDTA, centrifuged at 2000×g for 5 min, and resuspended in 1 ml of propidium iodide (PI) staining solution (30 µg/ml PI, 300 µg/ml RNase A in ...PBS). ...
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In vitro and in vivo effects of a recombinant anti-PSMA immunotoxin in combination with docetaxel against prostate cancer
... In this study we investigated the antitumor effects of a recombinant immunotoxin targeting the prostate specific membrane antigen (PSMA) in combination with DOC in vitro and in vivo. The immunotoxin consists of an ...
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MiR-145 functions as a tumor suppressor via regulating angiopoietin-2 in pancreatic cancer cells
... cultured cells using TRI- zol ® reagent ...miR- 145-F: 5 ′ -AAG GGA GTC CAG TTT TCC CAG GAA TCC-3 ′ , miR-145-R: 5 ′ -GTC GTA TCC AGT GCA GGG TCC GAG GTA TTC GCA CTG GAT ACG AC-3 ′ ; U6-F: 5 ′ -CTC ...
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The role of HIF lalpha and hypoxia in the preferential response of prostate tumours to microtubule targeting agents
... All cells lines were tested for mycoplasma infections every 2 months. The cell lines used in this study consistently tested negative for mycoplasma contamination. Cell lines were grown in their own specific ...
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Dual-strand tumor-suppressor microRNA-145 miR-145-5p and miR-145-3p ) coordinately targeted MTDH in lung squamous cell carcinoma
... miR- 145-5p (the guide strand of pre-miR-145) and miR-145-3p (the passenger strand of pre-miR-145) were significantly reduced in cancer tissues, suggesting that these miRNAs functioned as ...
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Up-regulated miR-145 Expression Inhibits Porcine Preadipocytes Differentiation by Targeting IRS1
... (DFAT) cells differentiation. In miR-145 overexpressed DFAT cells, adipogenesis was inhibited and triglycerides accumulation was decreased after hormone stimulation ...
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