E-Selectin
Role of ICAM-1 and E-selectin gene polymorphisms in pathogenesis of PAOD in Egyptian patients
... The statistical analysis was undertaken using SPSS software (version 17; SPSS Inc., Chicago, IL, USA). Descriptive statistics in form of mean and standard deviation for parametric data were used, while frequency and ...
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Leukocyte adhesion in angiogenic blood vessels Role of E selectin, P selectin, and beta2 integrin in lymphotoxin mediated leukocyte recruitment in tumor microvessels
... of E-selectin, P-selectin, VCAM-1, and ICAM-1,2,3 have been associated with tumors (12–16), the expression of VCAM-1 was found to be suppressed in the small tumor vessels ( , 80 mm) of the lung ...of ...
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Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
... expression of other established BAT genes [8–10]. Thus irisin can promote energy expenditure via thermogenesis [11]. Release of irisin has also been described from adi- pose tissue, suggesting that this hormone is an ...
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Usefulness of circulating E-selectin to early detection of the atherosclerotic process in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
... with E-selectin values reinforces a role of insulin resist- ance for atherosclerosis ...of E-selectin on the atherosclerotic process, our results may motivate further investigation of its ...
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Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins and Their Metabolites in an In-Vitro Model of Atherosclerosis
... Taken together, our results have shown that Peo-3-glc and Pet-3-glc, but not VA and MetGA, decrease the attachment of monocytes to endothelial cells via E-selectin reduction. These results were documented ...
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Severe inflammatory defect and reduced viability in CD18 and E selectin double mutant mice
... important venules, carrying the most leukocytes, are eliminated from contributing to leukocyte recruitment. In conclusion, we have identified an overlapping func- tion of CD18 integrins and E-selectin at a ...
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P selectin glycoprotein ligand 1–deficient mice have impaired leukocyte tethering to E selectin under flow
... or E-selectin–IgM chimeras or a control CD45-IgM chimera ...the selectin chimeras was detected by incubation with FITC-con- jugated goat anti–human IgM polyclonal Ab’s (Chemi- con International, ...
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E-selectin and vascular cell adhesion molecule-1 as biomarkers of 3-month outcome in cerebrovascular diseases
... Methods: Levels of four CAMs (E-selectin, P-selectin glycoprotein ligand-1, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 (VCAM-1)) and six other known biomarkers ...
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E selectin supports neutrophil rolling in vitro under conditions of flow
... to E-selectin expressed on the apical surface of L cell ...inhibited E-selectin-dependent adhesion under flow by > 65%, and there was a highly significant correlation between surface levels ...
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<p>Role of Galectin-9 in Atopic Dermatitis — Is It Mediated Through E Selectin? A Clinical and Immunohistochemical Study</p>
... Application of the primary antibody; one slide tissue sections is then incubated with gal-9 and the other with e selectin, horizontally in a humidity chamber over-night, at room temperature. Negative ...
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Early Clinical Markers for the Development of Bronchopulmonary Dysplasia: Soluble E-Selectin and ICAM-1
... in E- Selectin or ICAM-1 suggests that the effects of peri- natal factors on P-Selectin expression and cleavage are different from the same effects on the other two adhesion ...P- Selectin is ...
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Differential effects of fenofibrate versus atorvastatin on the concentrations of E-selectin and vascular cellular adhesion molecule-1 in patients with type 2 diabetes mellitus and mixed hyperlipoproteinemia: a randomized cross-over trial
... and E-selectin, but not with ...of E-selectin levels [8]. This decrease of E- selectin was weakly associated with the observed and well- known increase of HDL cholesterol during ...
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The Effects of Two Different Types of Resistance Training Exercise plus Omega-3-6-9 Supplement on E-selectin and ICAM-1 Adhesion Molecules in Young Overweight Men
... males with long-standing hyperlipidemia reduced cir- culating markers of endothelial activation [19].A lower risk of heart disease was associated with regular exer- cise programs and anti-inflammatory supplements [13, ...
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Investigation of the E-Selectin rs5368 (C468T) Single Nucleotide Polymorphism Role INA Group of Type Two Diabetes Mellitus Iraqi Patients
... ≥126 mg/dL (7.0 mmol/L), or HBA1C ≥ 6.5% (48 mmol/mol) [17]. Sixty-one healthy subjects (31males and 30 female) were included along with patients group as a control group. This control group consisted of non-diabetic ...
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Higher affinity oligosaccharide ligands for E selectin
... with E-selectin-Ig, P-selectin-Ig binding to immobilized BSA-sLea was blocked modestly by most oligosaccharides at 1 mM, with no substantial differences among ...
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Effects of low intensity and high intensity cycling with diesel exhaust exposure on soluble P selectin, E selectin, I CAM 1, VCAM 1 and complete blood count
... This is the first study to determine the effects of DE exposure with exercise of varying intensities on adhesion molecules and markers of inflammation. We found that sICAM-1 was significantly lower immediately following ...
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Soluble E-Selectin, Soluble L-Selectin and Soluble ICAM-1 in Bronchopulmonary Dysplasia, and Changes With Dexamethasone
... is a borderline significant association between low cortisol and increased risk of BPD (P ⫽ .08). We have observed that dexamethasone decreased sE-selectin and increased sL-selectin in plasma. Therefore, it ...
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Evaluation of serum amyloid A, soluble E-selectin and soluble E-cadherin as lung cancer biomarkers
... Methods: An observational and cross-sectional study comprised of three groups with 20 subjects each of proven lung cancer cases, patients with non-malignant respiratory diseases and healthy controls. Levels of SAA, ...
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Impaired Flow-Mediated Vasodilation, Carotid Artery Intima-Media Thickening, and Elevated Endothelial Plasma Markers in Obese Children: The Impact of Cardiovascular Risk Factors
... OBJECTIVES. Childhood obesity contributes to the development of adult obesity and subsequent cardiovascular disease. The present study aimed to assess vascular status (flow-mediated vasodilation [FMD], intima-media ...
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Syndecan 3 is selectively pro inflammatory in the joint and contributes to antigen induced arthritis in mice
... agent for 60 min at room temperature. Sections were in- cubated for 60 min with rabbit anti-murine CXCL1 polyclonal antibody (PeproTech) at 2 μg/ml or rat anti- murine E-selectin monoclonal antibody at 5 ...
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