Ectopic bone
Cholesterol accumulation caused by low density lipoprotein receptor deficiency or a cholesterol rich diet results in ectopic bone formation during experimental osteoarthritis
... Murine bone marrow derived macrophages were stimulated with oxidized LDL (oxLDL), whereupon growth factor presence and gene expression were ...contrast, ectopic bone formation was increased within ...
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Enhancing Ectopic Bone Formation in Canine Masseter Muscle by Loading Mesenchymal Stem Cells onto Natural Bovine Bone Minerals.
... a bone fill. This scaffold is indeed a bovine deproteinized bone sterilized by gamma radiation and possesses osteoconductive ...vivo bone formation capacity when being loaded with bone forming ...
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Tourniquet use in combat-injured service members: a link with heterotopic ossification?
... Hypoxic environments and endothelial cell damage have been previously linked with ossification in two murine HO models; however, there remains a knowledge gap and transla- tional concern between small-animal models and ...
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Non Traumatic Intracranial Heterotopic Ossification: A Case from Turkey
... The pathophysiology of neurogenic HO is not clear. Histologically, HO is characterized by local microvascu- lar changes and vascular stasis with encircled edema and swelling. Fibroblast and osteoblast proliferation, os- ...
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Morphological and molecular characterization of developing vertebral fusions using a teleost model
... Figure 4 Immunohistochemistry with TRAP, PCNA and Caspase 3. A: One sample from intermediate group showed weak positive TRAP staining (ar- row) at the ossifying border of the hypertrophic chondrocytes. B. Higher ...
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A 3 year old Girl with Fibrodysplasia Ossificans Progressiva
... The aim of the treatment is to prevent the formation of ectopic bone which causes ankylosis of joints and progressive immobility. Various modalities of treatment have been tried, such as steroids, mineral ...
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Betulinic acid synergically enhances BMP2-induced bone formation via stimulating Smad 1/5/8 and p38 pathways
... of bone defects is a dynamic and orchestrated process that relies on multiple growth factors and cell ...types. Bone morphogenetic protein 2 (BMP2) is a key growth factor for bone healing, which ...
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Efficient in vivo bone formation by BMP-2 engineered human mesenchymal stem cells encapsulated in a projection stereolithographically fabricated hydrogel scaffold
... cing bone healing without the use of native bone tissue [10, ...for bone repair, including femoral defects [13, 14], mandibular defects [15–17], and tibial defects [18, ...as bone ...
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Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2
... show ectopic bone formation with upregulation of Runx2 expression in vivo, Twist1 inhibits osteoblast differentiation in the skull and ribs without affecting Runx2 expression and without the development of ...
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A new platelet cryoprecipitate glue promoting bone formation after ectopic mesenchymal stromal cell-loaded biomaterial implantation in nude mice
... on ectopic bone formation and only after 8 ...enhanced bone formation compared with MSCs expanded in FCS ...enhanced bone-like tissue formation and that the addition of osteogenic medium ...
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Ethical Duties in Ectopic Pregnancy
... An ectopic pregnancy (EP), from Latin roots meaning “out of place,” is a pregnancy that does not correctly implant into its normal location in the endometrium of the ...
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Jin, Jieqi (2018): The effects of low molecular weight hyaluronan on the cementogenic, ligamentogenic and osteogenic differentiation of human mesenchymal stem cells (hMSCs) and periodontal ligament cells (PDL-hTERTs). Dissertation, LMU München: Medizinische Fakultät
... Type I collagen is an essential component of the dermis, bone, and tendon matrix. COL1A1 was also considered as an early marker of osteogenic differentiation (Weinreb et al. 1990). HMW-HA was reported to express ...
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Foxe view of lens development and disease
... an ectopic lens instead of a pituitary (Dutta et ...induce ectopic lens formation is intriguing, the ectopic induction of lens-specific gene expression might not follow the normal sequence of events ...
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Rapid cell culture and pre clinical screening of a transforming growth factor β (TGF β) inhibitor for orthopaedics
... ment bone markers in cultured human osteoblasts [7] and can lead to improvements in bone repair in ortho- paedic animal models [8-10]. However, in cultured murine cell lines, TGF-β acting through SMAD3 was ...
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Extrauterine pregnancies risk factors and management
... Objective: To study the clinical progress, risk factors, management, and outcomes of suspected ectopic pregnancy (EP). Design: Retrospective clinical case study. Population: All 184 patients hospitalized for ...
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Review of Tapered Femoral Stem Fixation in Cemented Total Hip Replacements
... To act as a composite beam, there must be perfect bonding at the stem-to-cement interface and the cement must provide good support. In these conditions the strain in the stem and the cement is identical at the interface ...
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Effect of ectopic high expression of transcription factor OCT4 on the “stemness” characteristics of human bone marrow-derived mesenchymal stromal cells
... Laboratory of our hospital. The informed consents were obtained from the parents or guardians, and the ethics approval was required according to the guidelines from the Children’s Hospital of Zhejiang University School ...
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Ectopic insulinoma: case report
... with ectopic insulin be- cause the positive findings determined by somato- statin receptor imaging were consistent with those indicated by ...of ectopic insu- linoma; therefore, some patients can be ...
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Ectopic cerebellar tissue in the occipital bone: a case report
... occipital bone in the posterior cranial fossa, which was revealed histopathologically to possess typical cerebellar structure with ...this ectopic mass was surrounded by a normal subarachnoid ...this ...
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Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate
... formed bone tissue ...formed bone and host cells were directly responsible for bone formation ...mediated bone formation by host BMSCs, suggesting that trans- planted BMSC-secreted paracrine ...
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