6. An efficient one-pot strategies for the synthesis of [1,3]oxazine derivatives
A Novel One Pot and Efficient Procedure for Synthesis of New Fused Uracil Derivatives for DNA Binding
... of 6-chloro-1-methyluracil followed by condensation of the product with different aromatic aldehyde gives the respective hydrazones which undergoes oxidative cyclization using thionyl chloride to obtain ...
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Polyethylene glycol (PEG 400) as an efficient and recyclable reaction media for the synthesis of substituted 4 (1 aryl 2 nitroethyl) 3 methyl 1H pyrazol 5 ol in catalyst free conditions
... 4-(1-aryl-2-nitroethyl)-3-methyl-1H-pyrazol-5-ol derivatives in good yields under the above conditions (Table ...2, 6- ...(IR, 1 H NMR, 13 C NMR, and ESI-MS) data and also by direct ...
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An Efficient Synthesis of Pyrido[2,3 d]pyrimidine Derivatives via One Pot Three Component Reaction in Aqueous Media
... its derivatives have been studied due to a variety of chemical and biological ...methods. One of the most promising approaches is using water as the reaction media ...
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An Efficient One pot Synthesis of some New Pyrazolyl Appended 1,3,4 Oxadiazole Derivatives as Antibacterial and Antioxidant agents
... The synthesis of 1,3,4-oxadiazole and its derivatives have established scrupulous attention for a long time because of its outstanding biological and pharmacological properties such as, antitubercular ...
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An efficient One pot Synthesis of 1, 4 Dihydropyridine Derivatives under Solvent free Condition
... the synthesis of 1, 4-dihydropyridines (1,4-DHP) ...substituted 1, 4- dihydropyridines exhibit a variety of biological activities such as cardiovascular, vasodilator, bronchodilator, ...
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Chitosan decorated copper nanoparticles as efficient catalyst for one-pot multicomponent green synthesis of novel quinoline derivatives
... the synthesis of quinoline derivatives via four- component one-pot reaction of P-Chlorobenzaldehyde, dimedone, ethyl cyanoacetate and ammonium acetate as the model reaction under ultrasound ...
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An efficient one pot synthesis of 2, 4, 6 triaryl pyridines and their in vitro antimicrobial activity
... and efficient synthesis of 2,4,6-triaryl pyridines is described by the one-pot condensation of substituted acetophenones, 1-phenyl-3-(4’-hydroxy/chloro phenyl) pyrazol-4- ...
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Phase Transfer Catalyzed Intramolecular Hydroaryloxylation and Hydroamination of C≡C Triple Bonds: An Efficient Synthesis of Benzo[b]furan and 3 Methyleneisoindoline 1 one Derivatives
... reaction was application to various propargylnaphthols and phenols, and for the most tested substrates, good results have also been obtained. Naphthols with an elec- tron-donating aryl group at propargylic position ...
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Synthesis and Biological Activities of [1,3] Oxazine Derivatives
... Chalcone derivatives were synthesized by carrying the reaction of benzaldehyde derivatives with p-amino ...heterocyclic derivatives of oxazine 5(a-f) ...( 1 H-NMR), Carbon-13 Nuclear ...
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Bronsted base catalysed efficient one pot three component synthesis of dihydropyrimidinone derivatives
... Table 1, attempt to select the suitable base catalyst from four different bases like MeONa, NaOH, KOH and t-BuOK was done at reflux ...Table 1, where it is clear that the t- BuOK is better catalyst being ...
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Vol 8, No 5 (2019)
... an efficient one-pot three-component synthesis of spirooxoindole derivatives involving isatin, malononitrile and enolizable ketones such as ...
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Novel and Efficient Microwave-Assisted Three Component Reaction for the Synthesis Ofoxazine Derivatives
... min, Anal. Found: C, 78.71; H, 6.28; N, 4.24, Calc. C20H19NO2: C, 78.66; H, 6.72; N, 4.59. IR (KBr, ímax/cm-1): 1027 (sym.C-O-C), 1223 (asym. C-O- C);1H NMR (DMSO-d6, 400 MHz, ä ppm): 1.21 (t, 3H, J = 8 Hz, ...
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Zirconium Oxide Nanoparticles as an Efficient Catalyst for Three-Component Synthesis of Pyrazolo[1,2-A][1,2,4]Triazole-1,3-Diones Derivatives
... 5-tetrahydro-1, 3-dioxo-2-phenylpyrazolo [1,2-a][1,2,4]triazole-6- carbonitrile from the three-component condensation reaction of 4-phenylurazole, malononitrile, and 4-chlorobenzaldehyde under ...
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An Efficient One Pot Multicomponent Synthesis of Spirooxindole Derivatives
... in one-step and easy operation to offer rapid access to drug-like molecules with greater efficiency, lower costs and atom economy [1] that are among the major challenges in organic synthesis in ...
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Efficient one pot synthesis of [1,2,4]triazolo[4,3 α][1,4] benzodiazepines derivatives
... system. 4H-[1,2,4]triazolo[4,3- α ] [1,4] benzodiazepine have not been object of new synthetic development in the last few years and recent reports on their preparation use only classical method. 9 This fact joined us to ...
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One pot Multicomponent Synthesis of Some Pyridine 3 carbonitrile Derivatives and Their Biological Evaluation as Cytotoxic Agent
... nicotinonitriles 1–6 lacked cytotoxic efficacy, yet the bicyclic pyrido[2,3-d]pyrimidine derivatives 7-18 showed overall mild to moderate activity, among which analog 17 (R = 3,4-(OCH 2 O)C 6 ...
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A facile, stereoselective, one-pot synthesis of resveratrol derivatives
... [2, 3], and are the subject of intense interest as potential leads for drug discovery as a conse- quence of their anticancer [4, 5] anti-inflammatory [6] and antioxidant properties ...
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One Pot Synthesis of Octahydroxanthene-1, 8-dione Derivatives using Magnesium Vanadium Oxide
... spectra of the Mg vanadate phases after calcination at 550°C they are in agreement with the standard spectra [4,5,6].In present work, we demonstrated nanoparticle of magnesium vanadium oxide, a heterogeneous mixed oxides ...
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Multi component, one pot synthesis of (1 (4 (1H imidazol 1 yl) phenyl) 1, 2 dihydronaptho[1, 2 e] [1, 3] 3 thione and 3 one derivatives under microwaveassisted conditions
... novel, efficient and one pot synthesis for the preparation of 1-(4-(1H-imidazol- 1-yl) phenyl)-1, 2-dihydronaptho [1, 2-e] [1, 3]-3-thione (or) ...
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One Pot Multi Component Synthesis of Novel Dihydropyridine Derivatives
... containing one nitrogen atom which is called as pyridine has considerable interest in different areas such as medicinal, pesticide, polymer and material ...the 1, 3-diphenyl pyrazole-4- carbaldehyde ...
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