EGF-like
Localization of heparin binding EGF like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques
... Heparin-binding EGF-like growth factor (HB-EGF) is a potent chemoattractant and mitogen for smooth muscle cells (SMC) in ...HB- EGF was dramatically decreased in young and middle-aged ...
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Gene expression during early ascidian metamorphosis requires signalling by Hemps, an EGF like protein
... It is very likely that the Hemps protein, a key regulator of earlier events of metamorphosis (Eri et al., 1999), plays a central role in the regulation of a large number of these genes, and antibody studies, as discussed ...
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Heparin binding EGF like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder
... and EGF-like molecules (4, 10, 11). Urinary EGF, produced by the distal segments of the kidney nephron, stimulates clonal growth (12) and ornithine decarboxylase activity (4) of transi- tional cell ...
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Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination
... In the present study, we hypothesized that tPA could facilitate OPC migration based on the following facts described above: (i) tPA facilitates neuronal migration [14], (ii) tPA can act on OPCs through its ...
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Original Article EGF like domain multiple 7 regulates the migration and invasion of prostate cancer cells
... Abstract: EGF like domain multiple 7 (EGFL7) and vascular endothelial growth factor (VEGF) were overexpressed in prostate cancer tissues. EGFL7 expression was induced by VEGF ex vivo. The aims of the ...
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Heparin binding EGF like growth factor contributes to reduced glomerular filtration rate during glomerulonephritis in rats
... The current state of knowledge of the mechanisms leading to glomerular immune injury is largely based on studies that have examined the very early phases of glomerular hemodynamic alterations after infusion of anti-GBM ...
11
449.pdf
... The results indicate that dpl00 could be affinity labeled with all the insulin-like and EGF-like growth factors tested (TGF- alpha, EGF, insulin, and IGF-I), and that radiolabel[r] ...
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Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10
... erythrocyte-binding like (EBL) proteins as well as the apical membrane anti- gen 1 (AMA1) play a central ...double EGF-like domain and a glycosylphosphatidylinositol (GPI) anchor at their C-terminus ...
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<p>The Current Understanding Of Asbestos-Induced Epigenetic Changes Associated With Lung Cancer</p>
... including EGF-like and two follistatin domains (TMEFF2), 86 that are detectable in the blood of lung cancer patients as tumours shed tumour DNA into the ...
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Kidney growth and hypertrophy: the role of mTOR and vesicle trafficking
... kidney, like other organs, grows in constant proportion to the rest of the ...by EGF-like peptides, and requires PI3K, PDK, AKT, mTORC2, and activation of mTORC1 through the combined effects of TSC ...
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Amphiregulin-EGFR Signaling Mediates the Migration of Bone Marrow Mesenchymal Progenitors toward PTH-Stimulated Osteoblasts and Osteocytes
... (A) EGF-like ligands are chemotactic factors for mesenchymal ...of EGF-like ligands was added in the lower wells of chemotaxis assays using rat mesenchymal ...
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An extra cysteine in one of the non calcium binding epidermal growth factor like motifs of the FBN1 polypeptide is connected to a novel variant of Marfan syndrome
... non-calcium-binding EGF- like motifs of the fibrillin polypeptide, most probably disturbing the formation of one of the three disulfide bridges known to be essential for the normal conformation of this ...
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Marfan phenotype variability in a family segregating a missense mutation in the epidermal growth factor like motif of the fibrillin gene
... all EGF-like motifs identified in fibrillin, and in all proteins that contain this ...the EGF-like motif of the fibrillin gene are not uniformly associated with severe disease, and that ...
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Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients
... of EGF-like growth factors, showed no differences between RA and ...for EGF-like growth factors between RA and OA synovia, but not for their receptors or ...
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Epidermal growth factor like, corneal wound healing substance in mouse tears
... radioimmunoassay. Removal of the submandibular glands, which produce large amounts of EGF, reduced plasma EGF to an undetectable level and also decreased the concentration of the EGF-like ...
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EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells
... by EGF and HB-EGF and their receptors and is involved in the proliferation of many cell types [14-16], we reasoned that EGF should be able to further stimu- late PCMO ...[17]. EGF was found ...
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The Human Papillomavirus Type 16 E5 Oncoprotein Inhibits Epidermal Growth Factor Trafficking Independently of Endosome Acidification
... analysis, EGF was prebound to EGF-starved HFKs at ...excess EGF and were warmed to 37°C for various periods of time prior to lysis in the presence of SDS and immunoprecipitation of ...
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Effect of blockade of the EGF system on wound healing in patients vaccinated with CIMAvax® EGF
... A 63 year-old man, with moderate chronic obstructive pulmonary disease. He was diagnosed with squamous cell carcinoma of the right lung in May 2003 and started vaccination in the same month. Three years later he was ...
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A Conserved GEF for Rho-Family GTPases Acts in an EGF Signaling Pathway to Promote Sleep-like Quiescence in Caenorhabditis elegans
... The ALA interneuron has been shown to influence C. elegans behavioral quiescence in several different scenarios. For in- stance, ablation of ALA disrupts quiescence during lethargus (Van Buskirk and Sternberg 2007), the ...
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APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis
... Three biomarkers have been described for IC in various patient groups including Chinese IC patients [3-5]. The first one is antiproliferative factor (APF), a low molecular weight frizzled-8 related peptide [6] that ...
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