EGFR Expression
Original Article TTF-1 and EGFR expression are related to EGFR mutation in lung adenocarcinoma
... of EGFR muta- tions. EGFR TKIs are shown to be superior to chemotherapy in first-line therapy of advanced NSCLC patients with EGFR ...Although EGFR mutations are strongly correlated to ...
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EGFR specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma
... + EGFR-positive laryn- geal carcinoma cell line UD-SCC-8 and ...low expression of EGFR, kindly provided by ...an EGFR expression, which was 675-fold higher in the cell line UD-SCC-8 ...
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Original Article Clinical significance of EGFR expression in tumor stroma of NSCLC
... of EGFR in tumor stroma of NSCLC were investi- ...of EGFR was evaluated in 145 patients with NSCLC using two different antibodies (sc-03 from Santa Cruz Biotechnology and ab2430 from ...of EGFR ...
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Phosphorylated EGFR expression may predict outcome of EGFR-TKIs therapy for the advanced NSCLC patients with wild-type EGFR
... of EGFR activation. Helfrich et al. showed not only EGFR mutant cell line (H3255) but also EGFR TKIs sensitive wild-type cell lines (H322 and Calu3) had higher pTyr1068 expression and more ...
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Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification
... of EGFR overexpression in ...protein expression and clinicopathologic features ...of EGFR expression, since many patients with EGFR expressing CRC failed to respond [10,11], or those ...
8
Predictive Values of EGFR Expression for the
... Abstract: Background: This retrospective study evaluates the survival effects of metronomic maintenance therapy with fluoropyrimidine in patients with stage III colorectal cancer (CRC) according to epidermal growth ...
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<p>Affibody-Modified Gd@C-Dots with Efficient Renal Clearance for Enhanced MRI of EGFR Expression in Non-Small-Cell Lung Cancer</p>
... assess EGFR expression, total protein samples were extracted from HCC827 and NCI-H520 cells in lysis buffer (RIPA) containing protease inhibitor ...anti-human EGFR monoclonal (1:1000, Abcam) and ...
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p53 and EGFR Expression in Glioblastoma Multiforme: An Immunohistochemical study
... represented tumors that progressed from low grade astrocytoma. This variant was more likely to show loss of chromosome 17p than tumors without p53 alterations (p<0.04). Seventy five percent of tumors with loss of one ...
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<p>RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro</p>
... of EGFR Tyr845, which is phosphory- lated in most hepatocellular carcinomas, 19 but also induced reduction of EGFR total protein amount in a dose-dependent manner in Huh7 cells (Figure ...of EGFR are ...
8
Overexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system
... demonstrate EGFR status as an independent prognostic ...the EGFR status, and this could explain the correlation of EGFR status and poor survival we ...for EGFR expression is lacking or ...
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Regulation of Cell Signaling by Mig6 and Sprouty2 in Cancers With Egfr Mutations
... wild-type EGFR. Additional data indicate that SPRY2 expression reduces EGFR endocytosis rate primarily by promoting EGFR expression, which overwhelms the saturable EGFR endocytic ...
170
EGFR as a therapeutic target for human, canine, and mouse ACTH secreting pituitary adenomas
... nuclear EGFR expression in both canine and human Cushing ...Nuclear EGFR local- ization has previously been reported in breast, ovarian, and thyroid cancers (46–48), likely as a result of ...
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Adrenal cortical neoplasms: a study of clinicopathological features related to epidermal growth factor receptor gene status
... Overall, EGFR expression was detected in 14 ACC cases ...addition, EGFR immunoreactivity was moderate (2+) in 3 cases and weak (1+) in 5 cases, whereas no specific staining was de- tected in 8 cases ...
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Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging
... between EGFR expression in cells and EGF uptake using fluorescence imaging To understand the EGFR specificity of EGF-HPPS nano- particles, two cell lines were chosen based on their endogenous ...
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<p>An <em>EGFR</em>-Amplified Cervical Squamous Cell Carcinoma Patient with Pulmonary Metastasis Benefits from Afatinib: A Case Report</p>
... of EGFR- ampli fi ed metastatic cervical squamous carcinoma patient bene fi ted from afatinib as a single ...of EGFR has been frequently seen in cervical squamous carcinoma, 5,10 whereas the EGFR ampli ...
5
Epidermal growth factor expression as a predictor of chemotherapeutic resistance in muscle-invasive bladder cancer
... Methods: The database from the Urology and Nephrology Center at Mansoura University was reviewed. BC patients who were treated with radical cystectomy and adjuvant chemotherapy for adverse pathological features or node ...
8
The therapeutic target of estrogen receptor alpha36 in estrogen dependent tumors
... and EGFR are mainly localized on plasma membrane, they have a positive correlation with each other in breast cancer and endometrial cancer ...[33]. EGFR signaling might induce the promoter activity of ...
12
Epidermal growth factor receptor (EGFR) overexpression in endometrial carcinoma: association with histopathologic parameters
... high expression of EGFR in endometrial ...67.1% expression of EGFR in a study in- volving 140 patients of endometrial ...of EGFR expression with grade and age, however no ...
5
Original Article Significance of elevated ERK expression and its positive correlation with EGFR in Kazakh patients with esophageal squamous cell carcinoma
... the EGFR-ERK pathway in Kazakh patients with esophageal squamous cell carcinoma (ESCC) have not been ...protein expression of EGFR and ERK in 90 ethnic Kazakh patients with ESCC and 48 adjacent ...
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High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in
... the expression level of EGFR, phosphorylated (p-) Akt or phosphorylated (p-) Erk could be used as factors to predict the overall survival (OS) in these patients was ...high EGFR expression ...
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