EGFR signaling
EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors
... of EGFR signaling in the AMPs, which is sufficient for their proliferation and might also promote their ...of EGFR activation used by tendon cells during muscle/tendon development is probably not the ...
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New Negative Feedback Regulators of Egfr Signaling in Drosophila
... We also tested for phenotypic effects of overexpression of CG6234 and Sulf1, using cDNA transgenes. We analyzed these genes further because in situ analysis (see below) dem- onstrated that both genes were expressed in ...
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The Regulation Of Egfr Signaling And Kras Tumorigenesis By Receptor Palmitoylation
... increases EGFR-dependent cell migration and enhances Gefitinib- induced ...(F) EGFR signaling is required for the increased chemotaxis of shDHHC20 ...
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Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair
... of EGFR in KYSE-150 and KYSE-150R ...of EGFR were detected in both cells, radiation induced a significantly higher level of phosphorylation in KYSE-150R cells, as compared with the level in KSYE-150 cells ...
10
Coordinated Targeting of the EGFR Signaling Axis by MicroRNA- 27a*
... the EGFR signaling ...of EGFR signaling pathway components decreased the overall effect of miR-27a* on HNSCC cell viability, suggesting the possibility that other signaling pathways may ...
11
Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer
... of EGFR in ...of EGFR-TKIs in GC cell lines and xenograft ...of EGFR signaling activation, including the phosphorylation of ...with EGFR-TKIs ...
11
Sulforaphane attenuates EGFR signaling in NSCLC cells
... attenuate EGFR signaling, and thus could prove useful for the treatment of TKI-resistant ...harbor EGFR double mutations (L858R and T790M), were the most sensitive to sulforaphane treatment in vitro ...
9
Mevastatin promotes healing by targeting caveolin-1 to restore EGFR signaling
... found EGFR signaling to be downregulated in tissue samples obtained from patients with DFUs compared with patients with AWs and that treatment with statins resensitized DFUs to EGF signaling by ...
14
A wave of EGFR signaling determines cell alignment and intercalation in the Drosophila tracheal placode
... As a candidate signal for coordinating the boundary smoothing and cell intercalation, we studied the expression pattern of EGFR signaling. Active ERK MAP kinase was visualized with an anti- double ...
10
Inhibition of EGFR Signaling Protects from Mucormycosis
... if EGFR signaling governs the establishment and/or progres- sion of mucormycosis in a well-established in vivo murine model of ...in EGFR die within the first 8 days of life (39), thus precluding our ...
13
Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics
... are signaling proteins. GSTP1, one of the EGFR- regulated proteins, associated with chemoresistance was ...an EGFR signaling network based on the identified EGFR-regulated ...
11
The maintenance and regeneration of the planarian excretory system are regulated by EGFR signaling
... how EGFR-5 might influence protonephridia function, we examined protonephridia regeneration in EGFR-5(RNAi) ...arborizations, EGFR-5(RNAi) animals displayed only short, partly posteriorly misoriented ...
12
Dominant Enhancers of Egfr in Drosophila melanogaster: Genetic Links Between the Notch and Egfr Signaling Pathways
... Further examination of the phenotypic interactions be- tween E@, H, and p revealed that reductions in E& activity enhanced both the bristle loss associated wit[r] ...
15
CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells
... in EGFR expression, we firstly performed quantitative PCR (qPCR) to evaluate the effect of siCD24 on EGFR tran- scriptional ...of EGFR mRNA was not affected in serum or serum-free conditions in ...
13
Original Article Curcumin inhibits oral squamous cell carcinoma proliferation and invasion via EGFR signaling pathways
... bated with primary antibodies over night at 4°C. The primary antibodies used in this study including anti-MMP-2, anti-MMP-9, anti-uPA, anti-uPAR, anti-EGFR, anti-p-EGFR, anti-Akt, anti-pAkt, anti-ERK1/2, ...
9
Brinker possesses multiple mechanisms for repression because its primary co repressor, Groucho, may be unavailable in some cell types
... Transcriptional repressors function primarily by recruiting co-repressors, which are accessory proteins that antagonize transcription by modifying chromatin structure. Although a repressor could function by recruiting ...
10
RANKL/RANK pathway abrogates cetuximab sensitivity in gastric cancer cells via activation of EGFR and c-Src
... between EGFR pathways and other tyrosine kinase receptors, might be involved in the interaction between EGFR and RANKL/RANK ...on EGFR signaling in GC cells. The activation of c-Src, ...
11
<p>RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro</p>
... Purpose: Histone deacetylase 3 (HDAC3) has been suggested to play a role in hepatocel- lular carcinoma (HCC). In the present report, we aimed to identify the effects of RGFP966, a speci fi c HDAC3 inhibitor, on the cell ...
8
Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity
... the EGFR signaling pathway, including MAPK and ...of EGFR and the downstream signaling pathway. And we found that EGFR expression is critical for the effect of LRIG1 on bladder cancer ...
9
Xie_unc_0153D_15129.pdf
... block EGFR signaling, showed that EGFR is required to prevent cardiac ...ERBB2 signaling through heterodimerization, this result is more likely due to the blockage of ERBB2 ...ERBB2 ...
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