endocrine cells
Synaptic like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones
... To define the role of glutamate in pinealocytes, the signal- transduction pathway by which glutamate inhibits melatonin synthesis was investigated. It was found that pinealocytes express functional metabotropic glutamate ...
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Menin determines K RAS proliferative outputs in endocrine cells
... pancreatic endocrine cells of the islets of ...different cells (1–3, 31, 32) and provides an explanation for the divergent role of KRAS in the transformation of these 2 major pancreatic cell types ...
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Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors
... pancreatic endocrine hormones such as insulin, glucagon, and somatostatin at day ...insulin-positive cells were glucagon-positive (double posi- tive) and some of them were also somatostatin-positive (triple ...
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Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling
... as endocrine cells normally delaminated from ductal epithelium during late embryonic ...delaminating endocrine cells is similar between embryonic tissue and TGF- induced hyperplastic ...12 ...
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Immunohistochemical study of the endocrine cells in the stomach and pyloric caeca of the mountain trout, Salmo trutta macrostigma
... Gastrointestinal endocrine cells dispersed through the epithelia and gastric glands of the alimentary tract, synthesize various kinds of gastrointestinal hormones and play in fish, as in mammals, important ...
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α-Synuclein in gut endocrine cells and its implications for Parkinson’s disease
... Parkinson’s disease (PD) is a debilitating neurodegenerative disease characterized by motor disturbances, including resting tremor, rigidity, and slow movements, as well as gastrointestinal symptoms, such as con- ...
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Pancreatic neurogenin 3 expressing cells are unipotent islet precursors
... 600 cells scored per embryo) or to total endocrine cells (right scale; adults, n4-5 mice, 60,000 and 150,000 cells scored at 2 and 10 months, ...of cells are labeled; this proportion ...
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Conditional inactivation of Myc impairs development of the exocrine pancreas
... acinar cells (Kawaguchi et ...epithelial cells of wild-type embryo ...epithelial cells for PDX1 revealed a significantly reduced epithelial mass with weakly branched structures in both buds of PMycKO ...
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Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish
... beta cells emerge during pancreas development in two sequential ...beta cells in zebrafish show high similarity to second wave mammalian beta cells in developmental ...and endocrine cell ...
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Mouse ES cells over expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin expressing cells
... The endocrine α , β , δ and PP cells are secreting glucagon, insulin, somatostatin and pancreatic polypeptide, ...pancreatic cells within the competent endo- ...progenitor cells (Offield et ...
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Spatiotemporal patterns of multipotentiality in Ptf1a expressing cells during pancreas organogenesis and injury induced facultative restoration
... pro- endocrine TFs (Pdx1, Ngn3). Our Ptf1a-lineage-labeled endocrine cells were often found next to duct-apposed small endocrine ...duct cells proper (Xu et al., 2008). Speculatively, ...
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Rfx6 is an Ngn3 dependent winged helix transcription factor required for pancreatic islet cell development
... pancreatic endocrine development, we abrogated Rfx6 protein expression in the zebrafish embryo by injecting two distinct antisense ...ghrelin-expressing cells together with a drastic reduction in the number ...
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The cytoskeleton as a barrier to exocytosis in secretory cells
... Since synapsini is not present in endocrine cells, the role of linking the granules to the cytoskeletal lattice is probably taken by fodrin, which is able to bind to granule membranes an[r] ...
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Enteric neuromodulators and mucus discharge in a fish infected with the intestinal helminth Pomphorhynchus laevis
... The endocrine cells with a basal euchromatinic nucleus were approximately pyram- idal ...thelial cells without a free border toward the gut ...These endocrine cells contained few ...
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HISTOPATHOLOGICAL AND ULTRASTRUCTURAL STUDIES OF THE EFFECT OF FENUGREEK SEED EXTRACT ON PANCREAS OF ALLOXAN INDUCED DIABETIC MICE
... Endocrine cells: In control group there were no obvious differences between alpha and beta cells in light microscope, while they were clearly identified and distinguished morphologically by the ...
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Overexpression of regenerating gene Iα appears to reflect aberration of crypt cell compartmentalization in sessile serrated adenoma/polyps of the colon
... crypts, endocrine cells and Paneth cells exist, in general, in prolif- erative and intermediate regions, and goblet cells are present only in the intermediate region [19]; however, in SSA/Ps, ...
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Pancreatic-Polypeptide in the Human Pancreas: Expression and Quantitative Variation During Development and in Ductal Adenocarcinoma
... retory cells of the pancreas. It gives rise to α cells which produce glucagon, β cells which produce insulin, and δ cells which produce somatostatin during weeks ...8–10. Cells ...
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Betacellulin and activin A coordinately convert amylase secreting pancreatic AR42J cells into insulin secreting cells
... AR42J cells possess exocrine and neuroendocrine ...neuron-like cells. In activin-treated cells, mRNA for pancreatic polypeptide (PP) but not that for either insulin or glucagon was detected by ...
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Abstract: Recent technical advances in the stem cell field have enabled the in vitro generation of
... Recently was reported the first generation of 3D human gastric organoids through directed in vitro differentiation of hESCs and hiPSCs. The authors recapitulated in vivo human stomach development by inducing first the ...
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Dr Anant Dattatray Dhanwate, Dr Swapna Ashok Ambekar and Dr Madhavi Dattatray Gaikwad
... EECs first appear in the gastric epithelium (at 9 to 10 weeks) as small proto-endocrine cells. Fairly differentiated EC-, D- and GLI-cells are observed by the 10th week. Pyloric G-cells and ...
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