Endometriotic lesions
Original Article Vascular endothelial growth factor receptor-2 inhibitor cediranib causes regression of endometriotic lesions in a rat model
... Abstract: Vascular endothelial growth factor (VEGF) receptor-2 plays an essential role in angiogenesis, and it also expressed in the glandular epithelium and stromal cells of ectopic endometrium. Cediranib is a protein ...
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Perineural invasion in endometriotic lesions contributes to endometriosis-associated pain
... in endometriotic lesions of the Pni (+) group (A), compared to that of the Pni (−) group ...in endometriotic lesions of the Pni (+) group than that of the Pni (−) group (C and ...
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Chronic pelvic pain and the role of exploratory laparoscopy as diagnostic and therapeutic tool: a retrospective observational study
... However, if the association between painful symptoms and endometriosis or adhesions is well accepted, the pre- cise causal relationship is still poorly understood. Endo- metriosis is still found in 2–50% of asymptomatic ...
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Original Article Depletion of NEDD9, a target gene of TGF-β, inhibits the proliferation and invasion of ectopic endometriotic stromal cells
... Endometriosis, first microscopically discovered by Karl von Rokitansky in 1860, is a chronic disease characterized by the growth of endo- metrial-like tissue outside the uterus [1]. Endometriosis affects 6% to 10% of ...
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The emerging use of aromatase inhibitors for endometriosis treatment
... While the majority of the literature suggests that letrozole may be effective in treating patients with endo- metriosis, not all clinical trials using letrozole were suc- cessful. An open-label prospective study in 2007 ...
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PubMedCentral-PMC5738435.pdf
... CD31 and Ki67 Immunohistochemistry. Paraformaldehyde fixed, paraffin embedded endometriotic lesions from mice were sectioned at 5 μm thickness. After deparafinization in series of graded alcohols and citro- ...
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Original Article NME1 suppression of endometrial stromal cells promotes angiogenesis in the endometriotic milieu via stimulating the secretion of IL-8 and VEGF
... of endometriotic lesions consisting of endometrial glands and stroma outside the uterine cavity ...otic lesions still remains controversial despite extensive ...these lesions are crucially ...
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Expression Pattern of Stemness-Related Genes in Human Endometrial and Endometriotic Tissues
... Many studies thus far have focused on the biomolecular and cellular characteris- tics of endometriosis compared to endo - metrium and with the possible molecular mechanisms at the basis of the develop- ment of ...
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Doxycycline reduces MMP-2 activity and inhibits invasion of 12Z epithelial endometriotic cells as well as MMP-2 and -9 activity in primary endometriotic stromal cells in vitro
... in endometriotic cells when compared to normal endometrium ...by endometriotic cells may de- grade the extracellular matrix leading to vascularization and growth of endometriotic lesions and ...
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ROLE OF MATRIX METALLOPROTEINASES IN THE DEVELOPMENT OF ENDOMETRIOSIS IN WOMEN WITH INFERTILITY
... Endometriosis, characterized by an ectopic growth of the endometrium outside the uterus, staying viable in the presence of immune control factors despite ectopic location, presents a certain «riddle» for the scientists ...
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Biological characteristics of endometriotic mesenchymal stem cells isolated from ectopic lesions of patients with endometriosis
... human endometriotic lesions was first reported in 2007, and a subsequent study demon- strated significant increases in the mRNA and protein levels of stemness-related markers, including UTF1, TCL1, ZFP42, ...
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Endometriosis and ovarian cancer - what they have in common?
... Ovarian tumors associated with endometriosis are commonly known as Endometriosis-Related Ovarian Neoplasms (ERONs) [18]. Besides ovarian cancer, several other tumors were also observed in women with endometriosis, ...
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Knockdown of vascular cell adhesion molecule 1 impedes transforming growth factor beta 1-mediated proliferation, migration, and invasion of endometriotic cyst stromal cells
... After excision, the human endometriotic tissue was rinsed with phosphate buffered saline (PBS). The endo- metrial lining was detached from the myometrium, minced in Hank’s balanced salt solution, and then digested ...
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Original Article The M2 polarization of macrophage induced by fractalkine in the endometriotic milieu enhances invasiveness of endometrial stromal cells
... to have phenotypic and functional alterations leading to poor phagocytotic capacity, which is closely related to the severity of endometriosis [12]. Our previous work has indicated that mac- rophages are involved in ...
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Download Download PDF
... with endometriotic cyst and those with non-en- dometriotic cyst, and its difference between endometriosis ...with endometriotic cyst and 25 women with non- endometriotic cyst, which had undergone ...
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Original Article Silencing of CTHRC1 inhibits proliferation and metastasis of endometriotic stromal cells
... Endometriosis (EM) is a common gynecological disorder which may lead to symptoms such as dysmenorrheal and even infertility. Histologi- cally, EM is defined as stroma outside the uter- ine cavity and the presence of ...
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ABDOMINAL COCOON IN ASSOCIATION WITH ADENOMYOSIS AND LEIOMYOMATA OF THE UTERUS AND ENDOMETRIOTIC CYST : UNUSUAL PRESENTATION
... It was possible that this patient may be having several unrelated pathology at one time, which were primary SEP, adenomyosis and leiomyomata of the uterus and endometriotic cyst. However it was unlikely as the ...
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An endometriosis classification, designed to be validated
... whether endometriotic cells are different from endometrial cells or whether only the environment is ...pocket lesions, estimated by their area or ...cystic lesions with the rAFS classification is ...
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Insulinlike Growth Factor-1Ec (MGF) Expression in Eutopic and Ectopic Endometrium: Characterization of the MGF E-Peptide Actions In Vitro
... Semiquantitative analysis of the IGF-1 transcript expression using PCR methods revealed that endometriotic cysts ex- pressed IGF-1 transcripts at a significantly lower level than eutopic endometrium and red ...
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Imageology features of different types of multifocal choroiditis
... inflammation lesions, inactive inflammation lesions, and secondary active CNV, secondary inactive CNV ...MFC lesions, single optical examination method is not sufficient for the detection and ...
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