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Endosomal trafficking

Endosomal trafficking of yeast membrane proteins

Endosomal trafficking of yeast membrane proteins

... membrane trafficking pathways transport molecules through the endosomal system of eukaryotic cells, where trafficking decisions control the localisation and activity of a diverse repertoire of ...

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Late Endosomal Trafficking of Alternative Serotype Adenovirus Vaccine Vectors Augments Antiviral Innate Immunity

Late Endosomal Trafficking of Alternative Serotype Adenovirus Vaccine Vectors Augments Antiviral Innate Immunity

... late endosomal compartment and the associated Ad innate sensing ...intracellular trafficking, we utilized Ad35k5, a chimeric Ad35 with its fiber knob domain replaced with that of Ad5, and Ad5f35, a chimeric ...

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Murine Cytomegalovirus Perturbs Endosomal Trafficking of Major Histocompatibility Complex Class I Molecules in the Early Phase of Infection

Murine Cytomegalovirus Perturbs Endosomal Trafficking of Major Histocompatibility Complex Class I Molecules in the Early Phase of Infection

... protein trafficking in the secretory ...perturbs endosomal trafficking in the early phase of ...early endosomal antigen 1 (EEA1)-positive and lysobisphosphatidic acid (LBPA)-negative ...

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Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

... of endosomal compartments that affect “transport” of antimicrobial drugs and is likely a com- mon pathway for macrophage scavenging ...for endosomal trafficking and HIV are not perfectly ...

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Early Steps in Cell Infection by Parvoviruses: Host-Specific Differences in Cell Receptor Binding but Similar Endosomal Trafficking

Early Steps in Cell Infection by Parvoviruses: Host-Specific Differences in Cell Receptor Binding but Similar Endosomal Trafficking

... and trafficking have been examined by using cells fixed at various times after uptake and then antibody stained for virus and cellular markers or by expressing green fluores- cent protein (GFP)-labeled ...of ...

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Local Cytoskeletal and Organelle Interactions Impact Molecular Motor-Driven Early Endosomal Trafficking

Local Cytoskeletal and Organelle Interactions Impact Molecular Motor-Driven Early Endosomal Trafficking

... early endosomal trafficking. Live-cell imaging of an endosomal cargo (endocytosed epidermal growth factor- conjugated quantum dots) combined with high-resolution tracking was used to analyze the ...

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Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus

Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus

... Receptors are considered necessary cell surface mol- ecules instrumental for successful virus infection [34]. Herpesvirus entry occurs via viral glycoprotein engage- ment of target cell receptor molecules. Those recep- ...

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Hepatitis C Virus Egress and Release Depend on Endosomal Trafficking of Core Protein

Hepatitis C Virus Egress and Release Depend on Endosomal Trafficking of Core Protein

... Earlier reports indicated that Rab5, an early endosomal protein, interacts with NS4B (31) and is required for HCV RNA replication. This effect was demonstrated in Rab5 small interfering RNA (siRNA)-transfected ...

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Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

... The observation of an ordered dAMP within a conserved binding site in the majority of the crystal structures of AAVs determined to date (20, 31, 36, 37) suggests a role for the interacting residues, particularly P422 and ...

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Endosomal and AP-3-Dependent Vacuolar Trafficking Routes Make Additive Contributions to Candida albicans Hyphal Growth and Pathogenesis

Endosomal and AP-3-Dependent Vacuolar Trafficking Routes Make Additive Contributions to Candida albicans Hyphal Growth and Pathogenesis

... vacuolar trafficking routes required for hyphal growth and virulence are ...two trafficking routes deliver material from the Golgi apparatus to the ...when endosomal trafficking is ...

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Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes

Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes

... ing, endosomal trafficking and axonal transport abnor- malities and induces gene expression changes that are reminiscent of early stages of sporadic ...

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Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

... Overexpression of the IFN-inducible antiviral protein IFITM3 has been linked to LE/L cholesterol accumulation (6, 10), and yet the functional relevance of this link, especially in the context of IFN-driven viral ...

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A measure of endosomal pH by flow cytometry in Dictyostelium

A measure of endosomal pH by flow cytometry in Dictyostelium

... To generate calibration curves, one must be able to impose a defined pH in endosomal compartments in order to determine fluorescence emission at known pH values. To test various protocols, we allowed cells to ...

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Rhinovirus-mediated endosomal release of transfection complexes.

Rhinovirus-mediated endosomal release of transfection complexes.

... abolished reporter gene expression mediated by HRV14. In- terestingly, only minor effects were seen when HRV2 was used in NIH 3T3 cells. In HeLa cells, reporter gene expression increased about 2.5- and 5-fold in the ...

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Sex Trafficking: A Gender Based Civil Rights Violation

Sex Trafficking: A Gender Based Civil Rights Violation

... sex trafficking from the hands of their profiteers and victimizers and taking them to safety and ...anti- trafficking organizations and efforts into a real “abolition movement”, is the attention and ...

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The Lost Sanctuary: Examining Sex Trafficking through the Lens of United States v. Ah Sou

The Lost Sanctuary: Examining Sex Trafficking through the Lens of United States v. Ah Sou

... Whether the domestication of international human rights norms against slavery and trafficking has created meaningful avenues of relief for trafficking victims in the [r] ...

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Asylum for Trafficked Women: Escape Strategies Beyond the T Visa

Asylum for Trafficked Women: Escape Strategies Beyond the T Visa

... Although the legislative history of the Act indicates concern for the victims of trafficking and recognizes that trafficking violates women's human rights, the T vis[r] ...

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Swedish Gender Equality for Trafficked Women? Radical Official Remedies and Ethnic Otherness

Swedish Gender Equality for Trafficked Women? Radical Official Remedies and Ethnic Otherness

... of trafficking is acknowledged in the preparatory work for the specific rules of the Aliens Act, and the relation between the trafficker and the trafficked woman is recognized as a power ...

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The Definition of Trafficking in Adult Persons for Various Forms of Exploitation and the Issue of Consent: A Framework Approach that Respects Peculiarities

The Definition of Trafficking in Adult Persons for Various Forms of Exploitation and the Issue of Consent: A Framework Approach that Respects Peculiarities

... The exploitation of the prostitution of others and other forms of sexual exploitation constitute the classical practices associated with the concept of trafficking since the end of the XIX century. They represent ...

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Trafficking in Human Beings in Albania

Trafficking in Human Beings in Albania

... concerning trafficking begins with Law ...human trafficking interpreted in a broader sense provided notions in domestic and international legislation, including the criminal activity related to the ...

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