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engineered nanomaterials (ENMs)

Structure-activity relationship models for hazard assessment and risk management of engineered nanomaterials

Structure-activity relationship models for hazard assessment and risk management of engineered nanomaterials

... of engineered nanomaterials (ENMs) make them ideal for several applications in almost every industrial ...of ENMs and their commercial use increase, it becomes more and more difficult to ...

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Innate Immune Responses to Engineered Nanomaterials During Allergic Airway Inflammation

Innate Immune Responses to Engineered Nanomaterials During Allergic Airway Inflammation

... utilizes engineered nanomaterials (ENMs), which are ultrafine particulates with at least one dimension less than 100 nm ...[5-7]. ENMs have a variety of chemical and physical properties that ...

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Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs

Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs

... experienced by the specific cell culture system under a real- istic exposure scenario. In other words, delivered dose (or the dose range) is mainly dependent on the cell type used in the study, and the administered dose ...

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The current state of engineered nanomaterials in consumer goods and waste streams: the need to develop nanoproperty-quantifiable sensors for monitoring engineered nanomaterials

The current state of engineered nanomaterials in consumer goods and waste streams: the need to develop nanoproperty-quantifiable sensors for monitoring engineered nanomaterials

... of nanomaterials in the environment or in medical ...make engineered nanomaterials so attractive for use in consumer products interact at the nano/bio ...

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Comparative lung toxicity of engineered nanomaterials utilizing in vitro, ex vivo and in vivo approaches

Comparative lung toxicity of engineered nanomaterials utilizing in vitro, ex vivo and in vivo approaches

... Although engineered nanomaterials (ENM) are currently regulated either in the context of a new chemical, or as a new use of an existing chemical, hazard assessment is still to a large extent reliant on ...

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IoT Applications in Future Foreseen Guided by Engineered Nanomaterials and Printed Intelligence Technologies a Technology Review

IoT Applications in Future Foreseen Guided by Engineered Nanomaterials and Printed Intelligence Technologies a Technology Review

... ‘engineered nanomaterials’ using inorganic, organic, and biomolecular building-blocks for improving the characteristics of microelectronic/microsystems (MEMS/NEMS) based sensors/actuators, ...

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In vitro detection of in vitro secondary mechanisms of genotoxicity induced by engineered nanomaterials

In vitro detection of in vitro secondary mechanisms of genotoxicity induced by engineered nanomaterials

... Background: It is well established that toxicological evaluation of engineered nanomaterials (NMs) is vital to ensure the health and safety of those exposed to them. Further, there is a distinct need for ...

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How to consider engineered nanomaterials in major accident regulations?

How to consider engineered nanomaterials in major accident regulations?

... Major accident regulations aim at protecting the population and the environment from possible accidental releases of chemicals. To achieve this goal, the regulations need to be reassessed in light of the development of ...

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Approaches to the safety assessment of engineered nanomaterials (ENM) in food

Approaches to the safety assessment of engineered nanomaterials (ENM) in food

... Most human involvement with food also modifies foodstuff at the nanoscale. Traditional cooking practices and industrial food processing are intended to improve the nutritional and storage properties of many food ...

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Environmental impact of engineered nanomaterials

Environmental impact of engineered nanomaterials

... of nanomaterials in consumer products. Engineered nanomaterials today are already being used in diverse commercial products in the fields of energy, sensing, food technology, electronics, ...

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A Review of Control Banding and Traditional Industrial Hygiene Sampling Methods for Determining Risk Assessment of Engineered Nanomaterials in the Workplace

A Review of Control Banding and Traditional Industrial Hygiene Sampling Methods for Determining Risk Assessment of Engineered Nanomaterials in the Workplace

... Currently, there are very few sampling methods that can be used to characterize exposure to ENM. NIOSH has developed the Nanoparticle Emission Assessment Technique (NEAT) to qualitatively determine the release of ...

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An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

... [2]. Engineered nanomaterials are manu- factured from a diverse group of substances each with an array of unique physicochemical characteristics, hence a varied range of materials need to be evaluated for a ...

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Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

... nm), ENMs can be synthesized in different shapes, and with different surface charges and functionalization, all of which are shown to influence ENM-induced toxicity ...to ENMs is more hazardous than ...

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An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials

An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials

... Fine tuning and troubleshooting experiments to eliminate toxicity of small intestine digest It is worth noting that in initial experiments, we observed that the small intestinal digesta without ENMs (control) was ...

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An integrated approach for the in vitro dosimetry of engineered nanomaterials

An integrated approach for the in vitro dosimetry of engineered nanomaterials

... industrially-relevant ENMs. Furthermore, the RID functions presented here for 20 ENMs in a variety of in vitro conditions can assist nanotoxicologists in ad- dressing dosimetry issues in their in vitro ...

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Engineered nanomaterials: exposures, hazards, and risk prevention

Engineered nanomaterials: exposures, hazards, and risk prevention

... of ENMs into the researcher ’ s breathing zone and laboratory environment and identified the variables affecting ...withdrew ENMs, releasing them outside the ...release ENMs (their production, ...

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Identifying the Potential Environmental Impacts of Engineered Nanomaterials

Identifying the Potential Environmental Impacts of Engineered Nanomaterials

... The second major challenge in nano-risk assessment is the importance of using more sophisticated metrics [22]. Traditional toxicology uses mass or concentration (mass/volume) to quantify dose, however for ...

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Longitudinal follow-up of health effects among workers handling engineered nanomaterials: a panel study

Longitudinal follow-up of health effects among workers handling engineered nanomaterials: a panel study

... of engineered nanoparticles, this study used the control banding nano- tool risk level matrix that was proposed by ...the nanomaterials were collected from industrial survey of individual factory, including ...

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Why a Prevention-Based Approach to Managing the Risks of Engineered Nanomaterials Makes Sense and How To Get There

Why a Prevention-Based Approach to Managing the Risks of Engineered Nanomaterials Makes Sense and How To Get There

... Modest risk to workers and consumers but some concern to developers End-of-life and environmen- tal risk Uncertain: capping agents promote spread Nano-composites may disinte[r] ...

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Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays

Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays

... In this study, which was part of the German national lead project NanoCare [18], we have evaluated and stan- dardized common in vitro assays measuring three differ- ent cytotoxic endpoints (oxidative stress, metabolic ...

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