Enhancer of split
Difference in transducin-like enhancer of split 1 protein expression between basal cell adenomas and basal cell adenocarcinomas - an immunohistochemical study
... Transducin-like enhancer of split 1 (TLE1) belongs to the Groucho/TLE family, and it functions in the “ off ” state in the Wnt/ β -catenin signaling ...
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The Effect of Polymorphisms in the Enhancer of split Gene Complex on Bristle Number Variation in a Large Wild-Caught Cohort of Drosophila melanogaster
... the Enhancer of split ...complete Enhancer of split locus revealed 550 frequent polymorphisms, where the minor allele was seen in at least 2/16 alleles, and 167 of these were geno- typed in a ...
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Genetic analysis of enhancer of split, a locus involved in neurogenesis in Drosophila melanogaster.
... A third, rather strong indication of the genetic complexity of E(sp1) is provided by the embryonic phenotype of the C4 group of mutants, in particular with respec[r] ...
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A tripartite interaction among alleles of Notch, Delta, and Enhancer of split during imaginal development of Drosophila melanogaster.
... If the phenotypic reversion were due to a modifying mutation extragenic to the E(sp1) locus, then we predicted that meiotic recombina- tion would lead to separation of [r] ...
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Two zebrafish Notch dependent hairy/Enhancer of split related genes, her6 and her4, are required to maintain the coordination of cyclic gene expression in the presomitic mesoderm
... Several observations suggest that Notch signalling is a central component of the oscillatory mechanism: 1 the cycling expression of mouse Hes1 depends on the Notch ligand Dll1 Jouve et a[r] ...
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Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster.
... The no-hole progeny is increased to 82% by addition of E8/E8; embryos of this class have no head defects either, just thin or disorganized ventral denticles, proba[r] ...
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The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells.
... That is to say, at least three genes of the E(spl)-C have to be present in the genome in order to obtain a noticeable rescuing effect. It seems thus that a res- cuing eff[r] ...
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Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.
... A basic region is found at the amino terminus of all four proteins, immediately followed by two clusters of mainly hydrophobic amino acids (Figure 3), reminiscent of the [r] ...
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Patterning of proneuronal and inter proneuronal domains by hairy and enhancer of split related genes in zebrafish neuroectoderm
... Role of the inter-proneuronal domains in neurogenesis Although neurog1, deltaA, neurod4 and elavl3 were ectopically expressed in the inter-proneuronal domains in the her3/her9 morphant e[r] ...
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The LRF transcription factor regulates mature B cell development and the germinal center response in mice
... Considering that a Lrf opposes Notch function at the HSC/progenitor levels 13 and b hairy and enhancer of split 1 Hes1, a Notch target gene, was upregulated in Lrf-deficient transitional[r] ...
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Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia
... antibodies: monocyte chemoattractant protein-1, MCP-1 (rabbit polyclonal IgG 1:100) (Santa Cruz Biotechnology, Cat. No. sc-28879); Notch-1 (rabbit polyclonal IgG 1:100) (Santa Cruz Biotechnology, Cat. No. sc- 6014-R); ...
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An in silico study on the interaction between RU486, a glucocorticoid antagonist and some regulatory proteins of lipid metabolism
... hairy enhancer of split -1 (HES-1), peroxisome proliferator- activated receptor γ (PPARγ), sterol regulatory element-binding protein 1c (SREBP-1c), cluster differentiation 36 (CD36), acetyl-CoA Carboxylase ...
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Original Article Involvement of Notch1/Hes signaling pathway in ankylosing spondylitis
... Keywords: Notch1, hairy enhancer of split, hip joint ligament, ankylosing spondylitis, mRNA expressions, protein expressions, clinical course, signaling pathway.. Introduction Ankylosing[r] ...
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To split or not to split: capital allocation with convex risk measures
... A special case takes place when the risk measure is additive over sub- portfolios. In that case the aggregation and diversification effects cancel each other out in the portfolio and the holder should be indifferent as ...
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To split or not to split: Capital allocation with convex risk measures
... a relation holds, and assuming that allocated risk capital carries a cost, the allocation does not give an incentive to split Y from the aggregate portfolio X, as since the this would yield a increase in the level ...
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D17 Surplus Annoucement pdf
... Description Split accumulator left shift Accumulator left shift Split left word left shift Split leftword right shift Split accumulator right shift Accumulator right shift Split right wo[r] ...
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Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites
... Fig. 4. Bridging of MEF2C-bound MEF2 sites by myocardin-935. (A) Schematic of the in vitro pull-down assay. (B) qPCR detection of co-precipitated MEF2 site 1 after incubation with biotinylated MEF2 site 2 in the presence ...
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Split and Rephrase
... We propose a new sentence simplifica- tion task (Split-and-Rephrase) where the aim is to split a complex sentence into a meaning preserving sequence of shorter sentences. Like sentence simplification, ...
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Regulatory logic driving stable levels of defective proventriculus expression during terminal photoreceptor specification in flies
... To determine how these transcription factors dictate cell type- specific levels of Dve expression, we analyzed the cis-regulatory logic controlling dve and identified two enhancers, yR7 enh and outer enh, that together ...
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