entorhinal cortex
Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology
... within the medial temporal regions (EC ⫹ hippocampus). Most impor- tant, this effect remained significant after controlling for hippocampal vol- ume. Finally, we found a robust rela- tionship between EC thickness and ...
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Comparative MR Analysis of the Entorhinal Cortex and Hippocampus in Diagnosing Alzheimer Disease
... the entorhinal cortex on MR images has been introduced (11), and the sensitivity of the entorhin- al cortex alone in diagnosing Alzheimer disease has also been reported (3, ...al cortex to ...
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MRI based volumetric analysis of entorhinal cortex in elderly subjects with mild cognitive impairment and in subjects with normal cognition to see effects of aging on volume of ERC
... A dedicated protocol was followed and images were acquired covering whole of ERC with tilted coronal T1W, 3-D magnetization-prepared rapid acquisition gradient-echo (MP-RAGE) sequence (4.5min) with a slice thickness of ...
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The role of the entorhinal cortex in epileptiform activities of the hippocampus
... Background: Temporal lobe epilepsy (TLE) is the commonest type of epilepsy in adults, and the hippocampus is indicated to have a close relationship with TLE. Recent researches also indicate that the entorhinal ...
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Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex
... EC: entorhinal cortex; IEI: inter-event intervals; LTP: long term potentiation; mGluR5: metabotropic glutamate receptor 5; MPEP: 2-methyl-6-(phenylethynyl)pyridine hydrochloride; NGF: nerve growth factor; ...
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Chenani, Alireza (2018): Influence of medial entorhinal cortex on CA1 population bursts. Dissertation, LMU München: Fakultät für Biologie
... Sharp wave-ripples are large amplitude, irregularly occurring LFP patterns that are observed in mammals during waking immobility and during slow wave sleep (SWS), as well as during consumma- tory behaviors (i.e. ...
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Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer’s disease
... The apolipoprotein E (APOE) ε4 allele associates with accelerating the conversion from amnestic mild cognitive impairment (aMCI) to Alzheimer’s disease (AD), whereas the protective APOEε2 allele appears to be against the ...
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Response Dynamics of Entorhinal Cortex in Awake, Anesthetized, and Bulbotomized Rats. <i>Brain Research</i> <b>911</b>(2)
... Rhythmic oscillations and coherent neuronal activity are thought to be important aspects of brain function because of their presence within and across many brain regions and their correlation with behavioral states [31, ...
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Lateral entorhinal cortex lesions impair local spatial frameworks
... A prominent theory in the neurobiology of memory processing is that episodic memory is supported by contextually gated spatial representations in the hippocampus formed by combining spatial information from medial ...
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Merging information in the entorhinal cortex: what can we learn from robotics experiments and modeling?
... the entorhinal cortex (EC), two brain structures highlighted by the discovery of place cells (O ’ Keefe and Nadel, 1978) and grid cells, respectively (Hafting et ...
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Excitatory microcircuits within superficial layers of the medial entorhinal cortex
... The hippocampus and parahippocampal regions are critically involved in learning and memory as well as in neurological dis- eases such as temporal lobe epilepsy and Alzheimer’s disease. More specifically, these regions ...
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Kümpfbeck, Franziska (2019): Physiological basis and function of depolarizing afterpotentials in the entorhinal cortex. Dissertation, LMU München: Fakultät für Biologie
... Layer II of the mEC is mainly composed of two major excitatory principal cell types, namely stellate cells (SC) and pyramidal cells (PC) , shown in Figure 1.. Two intermediate cell group[r] ...
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Polysomnography, brain volumetry, and mismatch negativity as early biomarkers of amnestic mild cognitive impairment progression
... Methods: This study was conducted on 60 amnestic mild cognitive impairment (amMCI) and 20 healthy control subjects submitted to baseline Montreal Cognitive Assessment (MoCA) scale, one-night polysomnography (PSG), ...
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Mixed-mode oscillations in pyramidal neurons under antiepileptic drug conditions
... Subthreshold oscillations in combination with large-amplitude oscillations generate mixed- mode oscillations (MMOs), which mediate various spatial and temporal cognition and mem- ory processes and behavioral motor tasks. ...
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Association of SLC1A2 and SLC17A7 polymorphisms with major depressive disorder in a Thai population
... cingulate cortex and dorsolateral prefron- tal cortex of patients with MDD ...orbitofrontal cortex of patients with MDD ...the entorhinal cortex of patients with either MDD or bipolar ...
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Sex modulates the ApoE ε4 effect on brain tau deposition measured by 18F-AV-1451 PET in individuals with mild cognitive impairment
... the entorhinal cortex, inferior temporal cortex, amygdala, fusiform gyrus, and parahippocampal cortex, but no significant ApoE ε4 by sex interaction effect on the entorhinal ...
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Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40
... Background: The relationship between the pathogenic amyloid β -peptide species A β 1 – 42 and tau pathology has been well studied and suggests that A β 1 – 42 can accelerate tau pathology in vitro and in vivo. The ...
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Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment
... the entorhinal cortex, the area of the brain first affected by the formation of neurofibrillary tangles, according to Braak ...of entorhinal cortex neurons to neurofibrillary tangle pathology ...
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Alterations in Cortical Thickness and White Matter Integrity in Mild Cognitive Impairment Measured by Whole Brain Cortical Thickness Mapping and Diffusion Tensor Imaging
... the entorhinal, middle tem- poral, parahippocampal, and superior temporal ...transentorhinal cortex and quickly spread to the entorhinal cortex and the ...the entorhinal and hippocampal ...
Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease
... entorhinal cortex]. B) Example of randomly selected area from the entorhinal cortex, which was imported in ...entorhinal cortex]. E) Example of a randomly selected area from the ...
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