Eph receptors
Simultaneous targeting of Eph receptors in glioblastoma
... these receptors. The EphA3, EphA2, and EphB2 receptors are recognized by eA5 [36] (Supplementary Table ...internalized Eph receptors [27] (Figure ...
17
Eph receptors and ephrin class B ligands are expressed at tissue boundaries in Hydra vulgaris
... rerio Eph receptor Eph3 ...melanogaster Eph (NP_726589); Caenorhabditis elegans VAB-1 (NP_494806); Ephydatia fluviatilis Protein Tyrosine Kinase ...melanogaster eph- rinB ...
8
Köhler, Jenny (2005): Imaging of the dynamics of Eph receptors and their ephrin ligands in mature hippocampal neurons. Dissertation, LMU München: Fakultät für Biologie
... EphB2 receptors (EphB2-C1) could in- duce reverse transcytosis of EphB2 clusters from these neurons into neighbouring ...the Eph/ephrin com- plexes in the opposite direction – from the neuron into the ...
196
Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum
... some Eph receptors, which are selectively enriched in the matrix compartment (Janis et ...and Eph receptors have been involved in the generation of distinct developmental compartments, such as ...
10
The role of the Eph signalling pathway in epithelialisation of the somites
... The Eph receptors were named as such as the first one identified was isolated from a erythropoietin-producing human hepatocellular carcinoma cell line (Hirai et ...f Eph-related receptors and ...
255
Weinges, Stefan (2006): Molecular dissection of ephrinB reverse signaling. Dissertation, LMU München: Fakultät für Biologie
... Eph receptors and their membrane-bound ligands, the ephrins, are unique in the receptor tyrosine kinase family because their signaling is bidirectional, through both the receptor and the ligand (Kullander ...
140
Eph/ephrin interactions modulate muscle satellite cell motility and patterning
... During development and regeneration, directed migration of cells, including neural crest cells, endothelial cells, axonal growth cones and many types of adult stem cells, to specific areas distant from their origin is ...
11
Eph and NMDA receptors control Ca2+/calmodulin dependent protein kinase II activation during C elegans oocyte meiotic maturation
... vertebrate Eph receptors can lead to cell adhesion or repulsion in migrating neurons, depending on the level of input (Pasquale, 2005; Poliakov et ...Thus, Eph receptors are capable of ...
13
Eph/ephrin signalling during development
... of Eph and ephrin proteins Eph receptors are subdivided into two subclasses, termed EphA and EphB, based on sequence similarity and their preference for binding a particular subclass of ...EphA ...
5
Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord
... B-type Eph receptor family in the mouse ventral spinal cord ...EphB receptors, as well as EphA4, as shown by in situ hybridization ...several Eph receptors and reveal that ephrinB2 ...
11
The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging
... and Eph B3 in vitro in a colorectal cell line (HT-29) and a mouse model ...and Eph B3 indi- cate that their coexpression suppresses cancer progression by cell-cell contacts and compartmentalization of the ...
8
Investigating the role of ephrins and their receptors in mouse folliculogenesis and ovulation
... and Eph receptors, and given that Eph- ephrin signaling regulates cellular adhesion (29), we wanted to determine the effect of EPHA5 signaling on GFSHR-17 and primary mouse GC adhesion (Figure 2-6 ...
187
Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells
... the EPH receptors [21], which are overexpressed in many malignancies [12–16] and which are often associated with a poor clinical outcome [13] as well as with a resist- ance to chemo- [31, 32] and ...
19
Paradoxes of the EphB1 receptor in malignant brain tumors
... Eph receptors are a subfamily of receptor tyrosine kinases. Eph receptor-mediated forward and ephrin ligand- mediated reverse signalings are termed bidirectional ...that Eph/ephrin signaling ...
10
Functional Analysis Of Receptor Tyrosine Kinases Sek1 And Elk In Neural Crest In The Xenopus Embryo
... its receptors and thus these neural crest cells would repel each ...truncated receptors may be due to masking of another as yet unidentified ligand for Sekl expressed in the fourth arch neural ...more ...
134
The role of the Eph ephrin signalling system in the regulation of developmental patterning
... the Eph family of fourteen receptors is identical in all ...mammalian Eph cDNAs, but of the many (>50) clones analysed none resemble ...degenerate Eph primer strategies (Lickliter et ...
10
EPH/ephrin profile and EPHB2 expression predicts patient survival in breast cancer
... The clinical role of EPHB2 in breast cancer is not well established. High EPHB2 protein expression has been associated with shorter overall survival [23]. The authors reported high EPHB2 cytoplasmic protein and mRNA ...
19
EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population
... and Eph receptors might affect monocyte chemotaxis, contributing to the development of ...the Eph/ephrin molecule is important for the developing cardiovascular system, as shown by the presence of ...
7
Effective Parameters in Contact Mechanic for Micro/nano Particle Manipulation Based on Atomic Force Microscopy
... for EpH biological micro particle with spherical, cylindrical, and circular crowned roller shape was used to investigate the effect of geometry on contact simulation process in ...two EpH and C3T3 cells ...
10
Original Article Orthodontic force influences the activity of osteoclasts in alveolar bone remodeling by regulating EphB4/ephrinB2 expression
... on Eph kinase activity and kinase-dependent signal- ing, whereas the reverse signal of ephrinB2 is dependent on the Src family kinases and other effector molecules [13, ...that Eph/ephrin-mediated ...
8