Ephrin ligands
Köhler, Jenny (2005): Imaging of the dynamics of Eph receptors and their ephrin ligands in mature hippocampal neurons. Dissertation, LMU München: Fakultät für Biologie
... of ligands of the EphB receptors, such as ephrinB2 and ephrinB3, in astrocytes that ensheath chains of migrating neu- roblasts in the adult subventricular ...their ligands in glial cell in the hippocampal ...
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Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model
... their ephrin ligands has also been implicated in human ...the ephrin-A5 ligand and its receptors, EphA4 and EphA7, in granule cell-precursor formation and in guiding cell ...of ephrin-A5, ...
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Drosophila Eph receptor guides specific axon branches of mushroom body neurons
... their Ephrin ligands have been shown to play roles in many aspects of axon guidance, including midline crossing at the optic chiasm, retinotopic map formation and motoneuron innervation of target muscles ...
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Roles of EphB3/ephrin B1 in feather morphogenesis
... The ephrin receptor (Eph) tyrosine kinases and their ephrin ligands are involved in morphogenesis during organ ...on ephrin-B1 and its receptor EphB3. Early in feather development, ...
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Paradoxes of the EphB1 receptor in malignant brain tumors
... Eph receptors are a subfamily of receptor tyrosine kinases. Eph receptor-mediated forward and ephrin ligand- mediated reverse signalings are termed bidirectional signaling. Increasing evidence shows that ...
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Growth cone navigation in substrate bound ephrin gradients
... of ephrin ligands are involved in the formation of topographic ...discontinuous ephrin distributions and stop at a distinct zone in the gradient while still undergoing filopodial ...substrate-bound ...
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Eph receptors and ephrin class B ligands are expressed at tissue boundaries in Hydra vulgaris
... A search for genes encoding Eph receptors and ephrin ligands was performed using the Hydra genome server (http://hydrazome.metazome. net/cgi-bin/gbrowse/hydra/) and the NCBI homepage (http://www.ncbi. ...
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Protein dynamics and conformational selection in bidirectional signal transduction
... The interactions between the Eph receptors and ephrins of the same subclass are promiscuous; however, crosssubclass binding is observed only for two receptors. EphA3 can bind ephrinB2, and EphA4 interacts with all nine ...
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Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum
... identified ephrin/Eph family members as guidance cues that regulate matrix/striosome ...its ephrin ligands displayed specific temporal patterns of expression and function that play a significant role ...
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Creutzfeldt, Claire (2003): The role of EphrinA for the retinotopic map formation in mouse visual cortex: An Optical Imaging study. Dissertation, LMU München: Medizinische Fakultät
... the ephrin-A knockout mouse, which would reduce functional defects in the cortical map and refine topographic ...Certain ephrin ligands and their receptors can be guidance molecules at the same time ...
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Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling
... of ephrin A ligands (Cheng and Flanagan, 1994; Dottori et ...B ligands (Gale et ...with ephrin ligands and can be involved in both cis- and trans-interactions (Hornberger et ...
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The role of the Eph ephrin signalling system in the regulation of developmental patterning
... its ephrin ligands in ...that ephrin A signal- ling might be triggered by interaction with Eph proteins and suggested that in some situations the Eph signal was not ...and ephrin genes are ...
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EphA/ephrin A reverse signaling promotes the migration of cortical interneurons from the medial ganglionic eminence
... some ephrin ligands can have attractive effects on specific sets of axons (Castellani et ...example, ephrin A3, which is expressed in the striatum, prevents MGE-derived cortical interneurons from ...
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Isolation and functional analysis of Xenopus ephrin-A3
... Indirect in vivo evidence for signal transduction through an ephrin was provided by work investigating the role of EphB2 (Henkemeyer et a l, 1996). Two mutations were introduced into the mouse EphB2 gene, and ...
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ALTERATION OF THE EPHA2/EPHRIN-A SIGNALING AXIS IN PSORIATIC EPIDERMIS
... contrast, ephrin-A1 is transiently down- regulated and subsequently increased along with ephrin-A3 at later ...and ephrin-A1 are coordinately induced by pro-inflammatory cytokines ...EGF ...
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Investigation of ephrin regulation during hindbrain segmentation
... the ephrin-B2 locus has been isolated in two PAC clones - 383-111 and 548-N22 (section ...the ephrin-B2 start codon by the ET-cloning m ethod of homologous recombination in bacteria and the plasm id ...
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Presenilin-dependent intramembrane cleavage of ephrin-B1
... type ephrin ligand, is cleaved by ADAM10/ Kuzbanian upon activation by its cognate receptor, and this process is implicated in Eph-ephrin-A mediated axonal repulsion ...that ephrin-B is shed by ...
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Ephrin B1 maintains apical adhesion of neural progenitors
... E14.5 embryos were decapitated and electroporations were performed as described (Arvanitis et al., 2010). Briefly, solutions containing 5 µg/µl expression vectors were mixed with 0.01% Fast Green and injected into the ...
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Exploring the Horizons of Ephrin B2 Receptor for Combating Paramoxyviridae Infection
... Upon finalizing the ligand (Berberine) and the receptor (Ephrin B2), the subsequent step in combating the infection would be by predicting the binding energies between the receptor and the ligand. To speculate ...
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trans Bis(4 aminopyridine κN)bis(succinimidato κN)copper(II) dihydrate
... environment; the Cu II atom lies on a center of symmetry. Both succinimidate and 4-aminopyridine ligands behave as mono- dentate ligands, which coordinate through deprotonated imidate and pyridine (not ...
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