epidermal growth
A functional polymorphism in the epidermal growth factor gene predicts hepatocellular carcinoma risk in Japanese hepatitis C patients
... Epidermal growth factor gene polymorphism 61 A/G in patients with chronic liver disease for early detection of hepatocellular carcinoma: a pilot study. Epidermal growth fac- tor 61A[r] ...
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Prognostic significance of Human epidermal growth factor receptor 2 expression in patients with resectable gastric adenocarcinoma
... Human epidermal growth factor receptor 2 (HER2), a target used in breast cancer treatment, is the second member of the epidermal growth factor receptor (EGFR) family and is a type of receptor ...
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Epidermal growth factor inhibits the hydroosmotic effect of vasopressin in the isolated perfused rabbit cortical collecting tubule
... Epidermal growth factor (EGF) is a 53-amino acid polypeptide which is a potent mitogen for cultured cells. The kidney has recently been shown to be a major site of synthesis for the EGF precursor. EGF ...
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M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop
... with epidermal growth factor receptor (EGFR) or heparin-bound epidermal growth factor (HB-EGF) neutralizing antibodies and HBEGF expression in peripheral blood mononuclear cells from ovarian ...
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Role of lapatinib in the first-line treatment of patients with metastatic breast cancer
... Abstract: Lapatinib is a dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR/ErbB1) and human epidermal growth factor receptor 2 (HER2/ErbB2). EGFR and HER2 overexpression ...
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HER2 therapy: Molecular mechanisms of trastuzumab resistance
... A potential mechanism by which resistance to targeted antibodies may develop is via disruption of the interaction between the therapeutic agent and the target protein. Resistance to trastuzumab was associated with ...
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Neuroinflammation in Autism Spectrum Disorders: the Role of High Mobility Group Box 1 Protein
... of epidermal growth factor (EGF), that is involved in growth and differentiation of cells in the CNS (60) and gastrointestinal tract ...with epidermal growth factor receptor (EGFR), ...
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The role of reversible ubiquitylation in EGF signalling
... Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of [r] ...
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6100.pdf
... EGFR(epidermal growth factor receptor) and the related HER-2 (human epidermal growth factor receptor 2) associated with breast cancer has allowed for the development of more targeted ...
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Prognostic value of <em>EGFR</em> and <em>KRAS</em> in resected non-small cell lung cancer: a systematic review and meta-analysis
... of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with ...mal growth factor receptor gene is not a prognostic factor for long-term outcome after surgical ...
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Identification of EGF-NF-κB-FOXC1 signaling axis in basal-like breast cancer
... the epidermal growth factor receptor (EGFR), an estab- lished BLBC marker, upregulates FOXC1 expression in BLBC cells through Ras/ERK and PI3K/AKT-mediated pathways ...tumor growth in mice ...
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Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis
... the epidermal growth factor receptor (EGFR). Human epidermal growth factor receptor (HER)2 and EGFR have attracted much attention in the medical literature over the past few years owing to the ...
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<p>Targeting the MET-Signaling Pathway in Non-Small–Cell Lung Cancer: Evidence to Date</p>
... survival, growth and ...of epidermal growth factor-receptor (EGFR) and mechanisms of resistance to tyrosine-kinase inhibitors (TKIs) demon- strated the importance of MET ampli fi cation as an escape ...
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<em>EGFR</em>, <em>KRAS</em>, <em>BRAF</em>, <em>PTEN</em>, and <em>PIK3CA </em>mutation in plasma of small cell lung cancer patients
... in epidermal growth factor receptor (EGFR), Kirsten rat sarcoma viral oncogene (KRAS), v-raf murine sarcoma viral oncogene homolog B1 (BRAF), phosphatase and tensin homolog (PTEN), and phosphatidylinositol- ...
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... CK20, epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) in relation to the clinical and pathological characteristics of patients with breast cancer ...
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EGFR gene copy number as a predictive biomarker for the treatment of metastatic colorectal cancer with anti-EGFR monoclonal antibodies: a meta-analysis
... at epidermal growth factor receptor (EGFR), were found effective in combination with chemotherapy or as a single agent for the treatment of chemotherapy-resistant mCRC ...
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Expression of amphiregulin predicts poor outcome in patients with pancreatic ductal adenocarcinoma
... malignancies in humans [4]. There is increasing recogni- tion that epidermal growth factor receptor variant III (EGFRvIII), the most common form of mutant EGFR, is an important target for cancer therapy. ...
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Hennes, Nadine Regina (2008): Untersuchungen zur Expression und Lokalisation des epidermalen Wachstumsfaktors (EGF) und seines Rezeptors (EGFR) im Intestinaltrakt des Schweines. Dissertation, LMU München: Tierärztliche Fakultät
... Expression and localisation of the epidermal growth factor (EGF) and its receptor (EGFR) in the intestinal tract of pigs.. The epidermal growth factor (EGF) is a peptide which exerts it[r] ...
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Exploring receptor tyrosine kinases-inhibitors in Cancer treatments
... Endothelial Growth Factor Receptor (VEGFR), Epidermal Growth Factor Re- ceptor (EGFR), Platelet-Derived Growth Factor Receptor (PDGFR), and Fibroblast Growth Receptor (FGR) while ...
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Challenging issues in molecular-targeted therapy
... whole epidermal growth factor receptor (EGFR) family of proteins contributes to tumor cell growth in numerous types of ...of growth factors to attract the endothelial cells that build new ...
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