epigenome-wide association study (EWAS)
Validation of differentially methylated microRNAs identified from an epigenome wide association study; Sanger and next generation sequencing approaches
... This study compared sequencing approaches to inves- tigate differentially methylated miRNAs associated with DKD identified from an epigenome-wide association study ...
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Epigenome-Wide Association Study of Wellbeing
... strong association with psychological and mental ...an epigenome-wide association study (EWAS) approach to identify differentially methylated sites associated with individual ...
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Epigenome-Wide Association Study of Aggressive Behavior
... an epigenome-wide association study (EWAS) to identify regions in the genome where DNA methylation level is associated with aggressive ...The association between aggressive behavior and ...
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Epigenome-Wide Association Study of Tic Disorders
... this study, we report results obtained in the first epigenome-wide association study (EWAS) of tic ...first study assesses the role of DNA methylation in tic disorders, and it ...
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An epigenome-wide association study meta-analysis of educational attainment
... Overlap between EWAS probes and published GWAS associations. To supplement our polygenic score analyses of the overlap between epigenetic and genetic associations, we next investi- gated whether our lead probes are ...
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DNA methylation and smoking in Korean adults: epigenome-wide association study
... EWAS: Epigenome-wide association study; EXOC3L4 : Exocyst complex component 3-like 4; F2RL3 : F2R-like thrombin/trypsin receptor 3; FAM53B : Family with sequence similarity 53 member B; FDR: ...
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Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families
... recent epigenome-wide study [63] has found a strong as- sociation between the same CpG site (cg06500161) that we observed and plasma ...recent epigenome- wide association ...
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Epigenome-wide association study of asthma and wheeze in childhood and adolescence
... Methods of causal inference such as MR help to define direction of causation in detected associations. Our MR analysis suggested a causal effect of asthma on DNA methylation at several CpG sites associated with asthma at ...
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Epigenome-wide association study of DNA methylation in panic disorder
... previous study reported that long-term medication for schizophrenia decreased DNA methylation of the GAD1 promoter, which was hypermethylated in a mouse model of schizophrenia ...present study were ...
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Epigenome-wide association study of asthma and wheeze characterizes loci within HK1
... Additional file 1: Method S1. Cohort-Specific DNA-M preprocessing steps. Methods S2. SVA to account for technical variations in ALSPAC. Additional file 2: This file includes supplemental Tables (S1–S8)— Table S1. ...
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An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study
... our study is the use of blood samples as DNA methylation is tissue ...our study is that due to the cross-sectional nature of our study, we cannot make statements about ...a study on weight ...
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Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms
... There were many strengths in our study analysis. We had a large sample size (n = 511), improving the power of our EWAS interrogation of 271,316 CpG sites. Furthermore, we obtained data collected from an ...
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Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci
... The level of cotinine is influenced not only by intake (such as smoking pattern and smoking quantity) but also by the rate of clearance of cotinine [28]. Therefore, we uti- lized a GRS for NMR (a proxy for nicotine and ...
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Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk.
... postmenopausal women and age at recruitment minus age at menarche for premenopausal women), number of pregnancies, and breastfeeding duration were consid- ered. The models were assessed for association with breast ...
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Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
... an association between methy- lation in this gene and HDL-C is ...the association we observed between DHCR24 methylation and HDL-C might be due to SNP variation in PCSK9 ...genome-wide ...
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Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis
... case-control study were stratified into four pathology sub-groups (in situ cases, ER-negative cases, ER-positive early onset <50 years, and ER-positive late onset >50 years, see Additional file 1: Table ...
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Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach
... higher total serum IgE levels compared to non-asthmatic children and (2) children maybe on asthma medication upon diagnosis, which leads to lowered serum IgE levels; for both reasons, asthma status maybe a predictor of ...
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Epigenome wide association study of SNP–CpG interactions on changes in triglyceride levels after pharmaceutical intervention: a GAW20 analysis
... this association is further explained by the presence or absence of a nearby SNP ...A study focusing on obesity found the interaction between CpG sites in an enhancer region interacts with CpG creating SNP ...
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Combining omics data to identify genes associated with allergic rhinitis
... A total of 31 controls and 48 cases for allergic rhinitis with asthma or 30 cases for allergic rhinitis alone were included in the epigenome-wide association study (EWAS) analysis. These ...
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Hypomethylation of FAM63B in bipolar disorder patients
... sequencing-based epigenome-wide association study (EWAS) performed on blood samples from 759 SZ cases and 738 control individ- uals identified differential DNA methylation in family with ...
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