epithelial and mesenchymal transition
Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway
... (TGF)-β2-induced epithelial-to-mesenchymal transition (EMT) plays an important role in the development of PVR, and EMT inhibition decreases collagen gel contraction and fibrotic membrane formation, ...
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Tetraspanin in oncogenic epithelial mesenchymal transition
... demonstrate that overexpression of the tetraspanin superfamily member TM4SF5 in human hepatocellular carcinoma cells causes cellular phenotypic changes that resemble classical descriptions of ...
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Nasal polyposis: insights in epithelial-mesenchymal transition and differentiation of polyp mesenchymal stem cells Emanuela Chiarella 1, Nicola Lombardo2 , Nadia Lobello 2, Annamaria Aloisio1 , Teodoro Aragona 3 Corrado Pelaia 4, Stefania Scicchitano1 , Heather Mandy Bond 1* and Maria Mesuraca1
... the epithelial-mesenchymal transition (EMT), a process in which epithelial cells lose their typical phenotype acquiring a mesenchymal ...of mesenchymal stem cells which can be ...
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A proximal activator of transcription in epithelial mesenchymal transition
... Epithelial-mesenchymal transition (EMT) is an important mechanism for phenotypic conversion in normal development and disease states such as tissue fibrosis and ...site. Epithelial cells ...
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Extramammary Paget disease of the vulva: immunohistochemical analysis of neoangiogenesis and epithelial-mesenchymal transition markers expression
... Recent data have shown that disease course may be influenced by some tissue markers related to tumor angiogenesis and epithelial/mesenchymal transition. Tumor angiogenesis is the rise of new blood ...
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Clinical significance of epithelial-mesenchymal transition
... of epithelial-mesenchymal transition (EMT), a process where cells change their epithelial towards a mesenchymal phenotype, has gained overwhelming attention especially in the cancer ...
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Epithelial Mesenchymal Transition: a double-edged sword
... endothelial mesenchymal transition), neural ...and epithelial po- larity is submitted to EMT, growth factors activate mem- brane receptors in such a manner that actin cytoskeleton is remodeled and ...
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Mechanisms and drivers of epithelial to mesenchymal transition in COPD
... involve epithelial-mesenchymal transition (EMT), including hepatic fibrosis [65, 80], kidney fibrosis [58, 79, 81] and non-COPD-related pulmonary fibrosis [58, ...bronchial epithelial cells in ...
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
... exhibited an annotated GeneSymbol and were sub- jected to characterize the functional processes in- duced by TGFβ by means of network analysis. The String protein-protein interaction database was quer- ied with the 428 ...
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Epithelial mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?
... Epithelial-mesenchymal transition (EMT) has become widely accepted as a mechanism by which injured renal tubular cells transform into mesenchymal cells that contribute to the development of ...
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OVOL guides the epithelial-hybrid-mesenchymal transition
... of Epithelial-to-Mesenchymal Transition (EMT) and its ...hybrid epithelial/mesenchymal (E/M) phenotype that has maximum cellular plasticity and allows migration of Circulating Tumor ...
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MicroRNA-328 inhibits migration and epithelial–mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells
... of mesenchymal markers such as N-cadherin, Snail, and ...the epithelial–mesenchymal transition process directly through a binding site on the CD44 3′ untranslated ...
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Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells
... Abstract: Quercetin, a flavone, is multifaceted, having anti-oxidative, anti-inflammatory, and anticancer properties. In the present study, we explored the effects of quercetin on the epithelial– mesenchymal ...
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Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells
... remodeled epithelial adherens junctions pathway, and manipulated nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated oxidative stress response signaling pathway in SCC25 cells with the involvement of a ...
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Metadherin regulates epithelial–mesenchymal transition in carcinoma
... carcinomas. Epithelial–mesenchymal transition (EMT) is a vital process in embryonic development, organ repair, and cancer ...and mesenchymal biomarkers, and negative correlations between MTDH ...
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Epithelial-Mesenchymal Transition in tumor microenvironment
... and epithelial-mesenchymal transition (EMT) is of potential importance for this process ...whereby epithelial cell layers lose polarity together with cell-cell contacts and then undergo a dra- ...
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Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy
... In our data, cultured cells from effluents of tuberculous pleurisy demonstrated two phenotypes. One phenotype, which was shown in five cases, revealed totally fibroblast- like cells under phase-contrast microscopy and ...
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Original Article MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer
... lated in GC cell compared with the expression in GES-1 cells (Figure 1C). Furthermore, we found that up-regula- tion of miR-211 suppressed the cells invasion ability compared with miR-NC group in SGC-7901 and BGC-823 ...
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Epithelial mesenchymal transition and its implications for fibrosis
... or transition” are comingled inap- propriately with the term “epithelial-mesenchymal ...(16). Epithelial- mesenchymal interaction refers to proximate paracrine cross-talk between tissue ...
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Epithelial to mesenchymal transition is associated with rapamycin resistance
... that epithelial-to-mesenchymal transition (EMT) confers rapamycin ...the epithelial marker E-cadherin protein is higher in rapamycin sensitive (RS) cells and mesenchymal breast cancer ...
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