Epithelial cell adhesion molecule
Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells
... against epithelial cell adhesion molecule (EpCAM), a protein that is overexpressed on colorec- tal adenocarcinoma cells, to develop EpCAM Apt-CUR-NP ...
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Original Article Loss of epithelial cell adhesion molecule (EpCAM) in infiltrative basal cell carcinoma
... Basal cell carcinoma (BCC) is the most common type of skin cancer and expresses high protein levels of the epithelial cell adhesion molecule (EpCAM, ...of adhesion and ...
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Downregulation of miR122 by grainyhead like 2 restricts the hepatocytic differentiation potential of adult liver progenitor cells
... Late fetal and adult livers are reported to contain bipotential liver stem/ progenitor cells (LPCs), which share surface markers, including epithelial cell adhesion molecule (EpCAM), with ...
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Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE®), is highly active against primary uterine and ovarian carcinosarcoma cell lines in vitro
... of epithelial cell adhesion molecule-1 (EpCAM), also known as TROP-1 or TACSTD1, is a known poor prognostic biomarker across a large number of carcinomas and carcinosarcomas [4, ...promotes ...
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Urinary EpCAM in urothelial bladder cancer patients: characterisation and evaluation of biomarker potential
... 2007). Epithelial cell adhesion molecule expression is a prognostic indicator in several cancers; in UBC, Brunner et al (2008) reported that high tissue levels of EpCAM are associated with ...
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CD24+/CD38- as new prognostic marker for non-small cell lung cancer
... about epithelial cell adhesion molecule (EpCAM) gene expression in NSCLC, a few studies have reported the upregulation of EpCAM in NSCLC cell lines and specimens, notably in squamous ...
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Expression of EpCAM in uveal melanoma
... The Epithelial Cell Adhesion Molecule (EpCAM) discov- ered in the early 1980's is a type I transmembrane glyco- protein encoded by the ga733-2 gene on chromosome 4 (locus ...of ...
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The intracellular domain of cell adhesion molecule 1 is present in emphysematous lungs and induces lung epithelial cell apoptosis
... chiolar epithelial cell apoptosis and a local imbalance in protease over anti-protease activities [2, ...lung epithelial cell adhesion molecule 1 (CADM1), also known as tumor ...
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Role of microRNAs in hepatocellular carcinoma: a clinical perspective
... EpCAM, epithelial cell adhesion molecule; AFP, alpha-fetoprotein; CDX2, caudal type homeobox transcription factor; GATA6, GATA binding protein 6; NLK, nemo-like kinase; T-ICs, tumor-initiating ...
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Lymphatic Imaging: Focus on Imaging Probes
... Comparison of mAbs targeting epithelial cell adhesion molecule for the detection of prostate cancer lymph node metastases with multimodal contrast agents: quantitative small-animal PET[r] ...
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A 3D in vitro model of the human breast duct: a method to unravel myoepithelial luminal interactions in the progression of breast cancer
... and epithelial cell adhesion molecule (EpCAM), for myoepithelial and luminal cells, respectively ...both cell types of the ductal tree [13, ...both cell types retained their ...
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Targeting FBPase is an emerging novel approach for cancer therapy
... EpCAM: epithelial cell adhesion molecule; H3K27Ac: histone H3 lysine 27 acetylation; HDAC: histone deacetylase; Dnmt1: DNA methyltransferase 1; ECAR: extracellular acidification rate; ERKs: ...
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Differential expression of the adhesion molecule Echinoid drives epithelial morphogenesis in Drosophila
... two cell types, which are specified coordinately during midoogenesis (Dorman et ...floor cell cytoplasm and thus also highlights the changes in floor cell shape that occur during appendage ...
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The Korean herbal medicine, Do In Seung Gi Tang, attenuates atherosclerosis via AMPK in high fat diet induced ApoE−/− mice
... Fig. 2 Effect of DISGT on reducing aortic lesions and expression of adhesion molecules in the aorta. a The aorta was collected from HFD-fed mice that were treated with DISGT or statin orally for 16 weeks. ...
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Troglitazone, a PPAR-γ activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-α
... lymphocyte cell line used in this assay expresses high levels of the α4β7 integrin, [35,44] which can interact with multiple ligands including mucosal addressin-1 (MAdCAM-1), as well as VCAM-1, L-selectin and ...
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Associations between outdoor temperature and markers of inflammation: a cohort study
... intercellular adhesion molecule-1 (sICAM-1) and vascu- lar cell adhesion molecule-1 (sVCAM-1) [18], which are interrelated markers of inflammation and endothelial ...
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Tretter, Jana Ylva (2017): Innovative therapy modalities for solid EpCAM-positive tumors. Dissertation, LMU München: Medizinische Fakultät
... High-Content Screening (HCS) is a method which uses living cells to investigate cellu- lar pathways in healthy and/or diseased cells and the effects of small inhibitory mole- cules on these pathways. Cells accomplish all ...
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Huang, Zhe (2017): EpCAM expression dynamics in cancer progression. Dissertation, LMU München: Medizinische Fakultät
... tumor cell migration activity (Driemel, Kremling et ...carcinoma cell population was sorted via FACS for differing EpCAM expression levels into two subpopulation, namely, EpCAM high and EpCAM low ...
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Treatment of malignant pleural effusions: the case for localized immunotherapy
... A recent clinical trial described the use of tumor infiltrat- ing lymphocytes (TIL) derived from MPE and malignant ascites in combination with cisplatin [10]. Effusion-derived TIL provided longer progression-free ...
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Proliferative ductular reactions correlate with hepatic progenitor cell and predict recurrence in HCC patients after curative resection
... biliary cell lineages ...single cell or strings of a few such cells in periportal or periseptal re- gions of regenerative nodules or hepatic ...stem cell factor c-kit [KIT] and prominin-1 ...
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