Epstein-Barr virus encoded RNA
Case Report Primary gingival diffuse large B-cell lymphoma: a case report and a review of the literature
... and Epstein-Barr virus-encoded RNA ...immunodeficiency virus (HIV)-antibody test was ...ciency virus-negative patients, and only 12 cases, including our own, have ever ...
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Systemic Epstein Barr virus positive T cell lymphoproliferative childhood disease in a 22 year old Caucasian man: A case report and review of the literature
... At morphology, neoplastic T cells are usually small and lack significant cytological atypia [6]. However, cases with pleomorphic medium-sized to large-sized lymphoid cells, irregular nuclei and frequent mitoses have been ...
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Clinicopathological and molecular features of responders to nivolumab for patients with advanced gastric cancer
... EBV- encoded RNA; EBV: Epstein-Barr virus; ECOG PS: Eastern Cooperative Oncology Group performance status; FISH: Fluorescence in situ hybridization; HER2: Human epidermal growth factor ...
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Regulation of Autophagic Activation by Rta of Epstein-Barr Virus via the Extracellular Signal-Regulated Kinase Pathway
... of Epstein- Barr virus (EBV) increases the membrane-bound form of LC3 (LC3-II) and LC3-containing punctate structures in EBV-positive ...interfering RNA, reduces the expres- sion of EBV lytic ...
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Profiling of Virus-Encoded MicroRNAs in Epstein-Barr Virus-Associated Gastric Carcinoma and Their Roles in Gastric Carcinogenesis
... Tissue samples.Viral miRNA expression was examined in tissues from 10 patients with surgically resected EBV-associated gastric carcinoma. An additional 5 NPC cases and 5 EBV-positive DLBCL cases were selected to measure ...
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Hyaline vascular variant of unicentric Castleman disease of the tonsil: a case report
... interfollicular areas. A characteristic lollipop appearance was also observed due to the onion-skin arrangement of the expanded mantle zone lymphocytes with a vessel penetrating the germinal center. No aberrant lymphoid ...
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Epstein-Barr Virus-Encoded RK-BARF0 Protein Expression
... Analyses of BARF0 transcripts in EBV-infected cells. In EBV-positive BL cells, LCLs, and NPC cells, transcripts en- coding the BARF0 ORF were recently shown to utilize a 5⬘ splice site and one of three different 3⬘ ...
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The signaling pathways of Epstein-Barr virus-encoded latent membrane protein 2A (LMP2A) in latency and cancer
... Abbreviations used: BCR – B-cell receptor; BL – Burkitt’s lymphoma; EBER – EBV- encoded small non-polyadenylated RNA; EBNA – EBV nuclear antigen; EBV – Epstein- Barr virus; ERK – extrace[r] ...
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Expression and Localization of the Epstein-Barr Virus-Encoded Protein Kinase
... Previously, we reported that EBV BGLF4 is an early gene based on its mRNA levels throughout viral reactivation in Akata cells in the presence of maribavir or acyclovir. The results demonstrated early kinetics comparable ...
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Cloning of the Rhesus Lymphocryptovirus Viral Capsid Antigen and Epstein Barr Virus Encoded Small RNA Homologues and Use in Diagnosis of Acute and Persistent Infections
... Epstein-Barr virus (EBV) is a human gammaherpesvirus in the lymphocryptovirus (LCV) genera which is associated with the development of several different malignancies, including Burkitt’s lymphoma, ...
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Conservation of sequence and function between the product of the 52-kilodalton immediate-early gene of herpesvirus saimiri and the BMLF1-encoded transcriptional effector (EB2) of Epstein-Barr virus.
... The amino acid sequence predicted for this protein shows it to be homologous to the EB2 transcriptional effector encoded by the BMLF1 open reading frame of Epstein-Barr virus EBV, the IE[r] ...
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The Epstein Barr virus EBNA1 protein modulates the alternative splicing of cellular genes
... that the RIP-Seq data are representative of the biological role of EBNA1 in binding to cellular RNAs. Interestingly, the enrichment of these RNAs in EBNA1 RIP are relatively low. This finding might suggest that the ...
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Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease
... Over the next weeks in hospital, she experienced pro- gressive abdominal bloating, malaise, dyspnea and night sweats without documented fevers. Computed tomog- raphy (CT) of her lungs revealed extensive, peripherally ...
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Genomic Diversity of Epstein-Barr Virus Genomes Isolated from Primary Nasopharyngeal Carcinoma Biopsy Samples
... Nonsynonymous mutations in protein-coding and noncod- ing genes. HKNPC6 genome contained a truncating mutation (C¡T, coordinate 79381), within the coding region of the BLLF1 gene. As a result, the transmembrane domain of ...
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Case Report Epstein-Barr virus associated T-cell lymphoproliferative disease misdiagnosed as ulcerative colitis: a case report
... The Epstein-Barr virus (EBV) is a ubiquitous virus that infects >90% of humans and persists for life [1]. EBV usually infects B cells, but it can also affect T and NK cells [2]. ...
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Epstein Barr Virus Infection Promotes Epithelial Cell Growth by Attenuating Differentiation Dependent Exit from the Cell Cycle
... To elucidate the mechanisms by which EBV promotes the transformation of normal epithelial cells into carcinomas, it is important to study latent EBV infection in non- transformed cells. While LCLs have been useful models ...
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Case Report Epstein-Barr virus-associated NK-cell lymphoproliferative disorder treated with haploidentical hematopoietic stem cell transplantation
... cells as the main target cells. Finally, lymph node biopsy pathology showed parts of the nor- mal structures were reserved while T lympho- cytes hyperplasia was found in the paracortex zone, with slightly bigger lymphoid ...
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Knockout of Epstein Barr Virus BPLF1 Retards B Cell Transformation and Lymphoma Formation in Humanized Mice
... BPLF1-KO virus resulted in decreased detection of EBV and suppressed tumori- ...BPLF1-KO virus may further support the idea of less- aggressive disease in the absence of ...
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Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase
... Human immunodeficiency virus type 1. HIV-1 is a retrovirus that causes AIDS and harbors extensive sequence variations, primarily due to recombination and to the lack of fidelity of its reverse transcriptase (49, ...
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Purified Hexameric Epstein-Barr Virus-Encoded BARF1 Protein for Measuring Anti-BARF1 Antibody Responses in Nasopharyngeal Carcinoma Patients
... antigenic domains were selected (Fig. 1A). Antibodies were generated against the three selected synthetic peptides, as well as against a purified full-length baculovirus-encoded BARF1- His fusion protein expressed ...
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