ER-β
Original Article The expression of transcription factor BORIS and its association with the estrogen receptor beta (ER-β) in cervical carcinogenesis
... different ER-β antibodies to determine those best at detecting ER-β through ...determine ER-β protein expres- sion in cervical tissues. We identified ER-β nuclear ...
14
Original Article The cervical malignant cells display a down regulation of ER-α but retain the ER-β expression
... of ER-β in the human uterine cervix [8, 9, 18] and its role in human cancer is not completely ...of ER-α, we identified nuclear expression of ER-β in the nor- mal cervical tissue with ...
9
Shabani, Naim (2008): Prognostische Signifikanz der Expression von Estrogenrezeptor alpha (ER-α) und beta (ER-β), Progesteronrezeptor A (PR-A) und B (PR-B) in Endometriumkarzinomen. Dissertation, LMU München: Medizinische Fakultät
... für ER-α, PR-A and PR-B haben wir Gewebschnitte vom humanen invasiven Mammakarzinom ...benutzt. ER-β Antikörper sind positiv am humanen Colongewebe getestet ...
61
DAX 1 expression in human breast cancer: comparison with estrogen receptors ER α, ER β and androgen receptor status
... of ER- β protein decreases in neoplastic breast cells, suggesting that ER- β could be an inhibitor of tumorigenesis [1,12], other studies have sug- gested that ER- β expression ...
9
Estradiol’s Salutary Effects on Keratinocytes Following Trauma-Hemorrhage Are Mediated by Estrogen Receptor (ER)-α and ER-β
... known ER subtypes, ER-α and ...of ER contributes to the effect of estrogen in ...for ER subtypes to determine which sub- type has a predominant role in the effects of estrogen on immune cell ...
8
Expression of voltage-gated sodium channel Nav1.5 in non-metastatic colon cancer and its associations with estrogen receptor (ER)-β expression and clinical outcomes
... and ER-β expression was detected by using immunohistochemistry (IHC) on tissue microarray constructed from paraffin-embedded ...high ER-β expression (OR = ...high ER-β expression ...
10
<p>Silencing of estrogen receptor β promotes the invasion and migration of osteosarcoma cells through activating Wnt signaling pathway</p>
... followed: ER β -F, 5 ′ -GCCGCCCCATGTGCTGAT-3 ′ ; ER β -R, 5 ′ -GG ACCCCGTGATGGAGGACTT-3 ′ ; β -catenin-F, 5 ′ -TGAGG ACAAGCCACAAGATTAC-3 ′ ; β -catenin-R, 5 ′ - TCCACC ...
10
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer
... both Er α and Er β are required for the tumour-promoting effects of ...either Er α or Er β become insensitive to the tumour-promoting effects of oes- ...Interestingly, Er ...
8
An overlooked connection: serotonergic mediation of estrogen-related physiology and pathology
... [25,66]. ER β regulates the antidepressant effect of E2 in mice; ERβ knockout mice fail to show the decrease in immobility usually induced by E2 doses in a forced swim test ...
10
Hochu-Ekki-to Treatment Improves Reproductive and Immune Modulation in the Stress-Induced Rat Model of Polycystic Ovarian Syndrome
... NGFR, ER-α, and ER-β, but not GR, were higher in the proestrous group than in the diestrous group ...of ER-α and ER-β relative to both control groups ...AR, ER-α, ...
22
Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells
... as ER β may potentially be targeted by specific drugs to potentiate its anticancer ...the ER β -specific agonist DPN potentiated the effects of RO, further confirming the important role played ...
10
Estrogen rescues heart failure through estrogen receptor Beta activation
... The improvement of heart function in HF mice treated with ER β agonist DPN was also associated with reduced cardiac fibrosis and increased cardiac angiogenesis, while the ER α agonist PP[r] ...
11
Relaxin deficiency results in increased expression of angiogenesis- and remodelling-related genes in the uterus of early pregnant mice but does not affect endometrial angiogenesis prior to implantation
... (Esr1), ER-β (Esr2), progesterone receptor (Pgr)), tissue remodeling (matrix metalloproteinase 14 (Mmp14), Timp3)), and other key genes identified in our microarray analysis (ankryn repeat domain 37 ...
14
Seel, Nina Nicola (2012): Expression des Östrogenrezeptors beta beim humanen duktalen Pankreasadenokarzinom und Inhibition der Tumorprogression durch Einsatz des selektiven Östrogenrezeptormodulators Raloxifen. Dissertation, LMU München: Tierärztliche Fakultät
... In früheren Studien wurde gezeigt, dass Raloxifen (RAL) an ER α und ER β gleichermaßen mit ähnlicher Affinität bindet [153]. Dabei agiert Raloxifen am ER α als Agonist/Antagonist und[r] ...
117
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy
... that ER β expression pro- motes the invasion and metastasis of breast cancer and that high ERβ level is linked with poor prognosis [7], multiple studies have demonstrated that ER β is an ...
18
The Expression of Estrogen Receptors in Hepatocellular Carcinoma in Korean Patients
... α β as androgen receptor (AR), in hepatocellular carcinoma (HCC) is thought to be correlated with prognosis, survival, and male prevalence of ...Wild-type ER- and AR were α expressed in all of the samples ...
6
Valproate pretreatment protects pancreatic β-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3β
... of ER stress-induced CHOP expression in INS-1 ...palmitate-induced ER stress via CHOP, up-regulation of CHOP expression cannot be the only mechanism that GSK-3β promotes the apoptosis during palmitate ...
11
Original Article Topical application of 8DSS induces anagen hair growth in telogenic mouse skin
... the Wnt/β-catenin signaling pathway, and en- hanced expression of wnt10b activates the Wnt/β-catenin signaling pathway in the regula- tion of hair growth. In addition, several studies have demonstrated that ...
10
Tamoxifen may prevent both ER+ and ER breast cancers and select for ER carcinogenesis: an alternative hypothesis
... that ER- cancers can emerge over time after exposure to tamoxifen. ER+ primary tumors may recur as ER- metastases in up to 20% of cases ...with ER+ or progesterone receptor posi- tive (PR+) ...
6
Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice
... diabetes, including Akita mice, which harbor a heterozygous mutation in Ins2 (Ins2 WT/C96Y ), and leptin receptor–deficient (Lepr –/– ) mice, resulted in an increase in b cell mass and ameliorated hyperglycemia. The ...
13