Erythrocyte binding
Possible Mimics of Duffy Binding Protein-II for Plasmodium vivax Binding Endothelial Cells or Binding Plasmodium falciparum by Mimicking Epitope on Erythrocyte Binding Antigen-175 A
... neuraminyl (α 2->6’) galactosyl 4’ (di-hydrido) sulfo (β 1->3) N-acetamido deoxy galactosaminyl 6 (di-hydrido) sulfo di- (hydrido) di-phospho serinyl (di-hydrido) sulfo tyrosine dipeptide and N-acetamido deoxy ...
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PfRON3 is an erythrocyte binding protein and a potential blood stage vaccine candidate antigen
... To investigate the erythrocyte-binding activity of PfRON3, GST-tagged PfRON3-I, II, III and IV (Figure 1), and GST (negative control) were expressed in E. coli BL21 [18] and purified on glutathione − ...
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Receptor specificity and erythrocyte binding preferences of avian influenza viruses isolated from India
... Introduction: Hemagglutination (HA) and hemagglutination inhibition (HI) assays are conventionally used for detection and identification of influenza viruses. HI assay is also used for detection of antibodies against ...
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Sequence similarity between the erythrocyte binding domain of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV 1 strain MN reveals a functional heparin binding motif involved in binding to the Duffy antigen receptor for chemokines
... both binding properties of chemo- kines; to glycosaminoglycans (GAGs) or to sulfated tyro- sines on chemokine ...for binding [30], and the HBM may interact with this as ...HIV binding and may inter- ...
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Plasmodium yoelii Erythrocyte Binding like Protein Modulates Host Cell Membrane Structure, Immunity, and Disease Severity
... ABSTRACT Erythrocyte-binding-like (EBL) proteins are known to play an important role in malaria parasite invasion of red blood cells (RBCs); however, any roles of EBL proteins in regulating host immune ...
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Evidence for Diversifying Selection on Erythrocyte-Binding Antigens of Plasmodium falciparum and P. vivax
... The erythrocyte binding A genetic map and recombination parameters of the human motif of Plasmodium vivax duffy binding protein is highly polymor- malaria parasite Plasmodium ...
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Erythrocyte binding assays reveal higher binding of Plasmodium knowlesi Duffy binding protein to human Fya+/b+ erythrocytes than to Fya+/b erythrocytes
... the binding level was quantita- tively determined by counting the number of rosettes in the erythrocyte binding assay, and the difference in the mean number of rosettes obtained in the assays for Fy ...
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A Novel Erythrocyte Binding Protein of Plasmodium vivax Suggests an Alternate Invasion Pathway into Duffy Positive Reticulocytes
... EBP2-reticulocyte binding was ...reticulocytes. Binding inhibition was quanti- fied by determining the number of rosettes (COS7 assay) or number of reticulocytes with bound EBP2 (flow cytometry) in the ...
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Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV 1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines
... introduced similar alanine mutations into three posi- tively-charged amino acids of each of the three P. know- lesi EBPs at the polycationic site. In all 3 cases this eliminated normal binding to rhesus ...
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Immunogenicity of the Plasmodium vivax merozoite surface protein 1 paralog in the induction of naturally acquired antibody and memory B cell responses
... against erythrocyte binding, approximately 75% of high responders and ...PvMSP1P-19 binding to ...SP1P-19 binding to erythrocytes during acute phase, and they can maintain this antibody after ...
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Single-Chain Antibody Fragment Specific for Plasmodium vivax Duffy Binding Protein
... The erythrocyte-binding capabilities of several proteins have been examined, including merozoite surface protein 1, reticulocyte binding protein, and DBP, which have high binding affinity to ...
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Identification of Gangliosides GD1b and GT1b as Receptors for BK Virus
... BKV binding to and interaction with human erythrocyte membranes and determined that this interaction was dependent on a neuramin- idase-sensitive, proteinase K-resistant ...
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An Erythrocyte Cytoskeleton-Binding Motif in Exported Plasmodium falciparum Proteins
... falciparum erythrocyte membrane protein 1 (PfEMP1) is inserted (11, 12, ...RBCs. Binding to endothelial cells sequesters infected RBCs in the microvasculature, which pre- vents the clearance of the infected ...
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Human erythrocyte protein 4 1 is a phosphatidylserine binding protein
... liposome binding to control ...saturable binding with the extent of binding being proportional to the liposome PS ...PS binding protein and may be involved in the molecular mechanisms that ...
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Functionally Abnormal Na+ K+ Pump in Erythrocytes of a Morbidly Obese Patient
... H]ouabain binding to intact cells, as well as the enzymatic activity of the (Na + -K + )- dependent ATPase in erythrocyte membranes were found to be markedly increased compared with control cells (18-fold ...
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Abnormality of glycophorin alpha on paroxysmal nocturnal hemoglobinuria erythrocytes
... major erythrocyte sialoglycoprotein. The pattern of binding of nascent C3b was the same for normal and PNH ...C3b binding to a different membrane constituent did not appear to account for the greater ...
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Sendai virus-erythrocyte membrane interaction: quantitative and kinetic analysis of viral binding, dissociation, and fusion.
... 87-95 0022-538X/86/040087-09$02.00/0 Copyright C 1986, American Society for Microbiology Sendai Virus-Erythrocyte Membrane Interaction: Quantitative and Kinetic Analysis of Viral Binding[r] ...
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Adhesion analysis of different PfEMP1 variants to CD36, ICAM-1 and primary endothelial cells
... the binding of the used isolates on ICAM- 1 using standard binding assays including the binding to primary ...the binding of IT4-ICAM-1 isolates to understand the binding phenotypes and ...
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Relationship of insulin binding and insulin stimulated tyrosine kinase activity is altered in type II diabetes
... The insulin receptor contains an alpha subunit with insulin binding properties and a beta subunit with insulin-stimulated tyrosine kinase function. Preparations containing insulin and insulinlike growth factor I ...
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Molecular defect in the sickle erythrocyte skeleton Abnormal spectrin binding to sickle inside our vesicles
... sickle erythrocyte membrane skeleton have been described, there is little quantitative data on the function of the proteins that compose the ...membrane binding site, and found sickle erythrocytes to have ...
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