essential genes
Essential Genes And Their Role In Autism Spectrum Disorder
... lethal genes in knockout mice and genes responsible for cell-based ...of genes and pathogenic variants identified by sequencing studies of complex human ...
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Silencing of essential genes within a highly coordinated operon in Escherichia coli
... Cross-sensitization of ileS and lspA-silencing strains to globo- mycin and mupirocin could not be reduced by complementation, indicating the complexity in expression and regulation of the two overlapping essential ...
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Protein disorderness based prediction of essential genes of Saccharomyces cerevisiae: A machine learning approach
... identify essential genes of prokaryotes through wet lab and in-silico ...identifying essential genes of the organisms in the wet lab has been gene knock-out experiments (Kemphues et al) where ...
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Combining Genome-Scale Experimental and Computational Methods To Identify Essential Genes in Rhodobacter sphaeroides
... identify essential genes and the fitness contributions of nonessential genes on a genomic scale ...important genes using NGS data of transposon ...
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In Vivo Validated Essential Genes Identified in Acinetobacter baumannii by Using Human Ascites Overlap Poorly with Essential Genes Detected on Laboratory Media
... of essential gene ...of essential gene screens or extrapolating from these results to computationally select antimicrobial drug targets or predict essential genes in other ...media. ...
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Genomewide Identification of Essential Genes and Fitness Determinants of Streptococcus mutans UA159
... certain genes are conditionally essential; that is, they may be required for growth in one environment, but not in ...study, genes were designated essential under the conditions tested if they ...
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Essential genes in the hDf6 region of chromosome I in Caenorhabditis elegans.
... Lethal screeningusingsDp2: In order to screen for lethal mutations of genes in the hDf6 region of chromosome I , the duplication sDp2 was used as previously described (HOWELL [r] ...
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Nonsense mutations in essential genes of Saccharomyces cerevisiae.
... Mutants containing an ochre mutation in any essential yeast gene give rise to nonsectoring, white colonies, since cell growth is dependent on the presence of the plas[r] ...
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ESSENTIAL GENES AND DEFICIENCIES IN THE UNC-22 IV REGION OF CAENORHABDITIS ELEGANS
... The lethal mutations will be tested for suppression by the informational suppressor, sup-7 X, to identify null alleles of the let genes (WATERSTON 1981). In addition to t[r] ...
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High throughput screen of essential gene modules in Mycobacterium tuberculosis: a bibliometric approach
... These essential genes were fallen in 307, 326, 297, 310 and 316 operons in H37Rv, H37Ra, CDC1511, F11 and KZN1435, respectively (Table ...of essential genes ...more essential ...
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Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways
... identify essential genes in vitro (7–16) and in vivo ...condition, genes for numerous essential central metabolic pathways can be rendered dispensable through ...of genes as ...
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GENETIC ORGANIZATION OF THE REGION AROUND UNC-15 (I), A GENE AFFECTING PARAMYOSIN IN CAENORHABDITIS ELEGANS
... Pre- viously identified genes in this region were mapped, and new mutations were induced with EMS in order to identify essential genes around unc-15.. Twenty of these were ame[r] ...
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Fitness Landscape of the Fission Yeast Genome
... These separate fits to the model resulted in similar distri- butions of states between chromosome arms for both the coding regions and introns of essential genes, supporting con- sistent convergence of the ...
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Analyses of amber mutants of Salmonella phage SPN3US
... identified essential proteins in ...identified essential genes in SPN3US, and it helped to verify the identified similar proteins in the ϕKZ-related phages from the previous ...
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In Vivo Gene Essentiality and Metabolism in Bordetella pertussis
... the genes involved in ...117 genes were identified as conditionally essential at 1 day postinfection, and 169 genes were identified as con- ditionally essential at 3 days ...identified ...
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Analysis of β-1,3-Glucan Assembly in Saccharomyces cerevisiae Using a Synthetic Interaction Network and Altered Sensitivity to Caspofungin
... for genes whose deletion led to altered sensitiv- search revealed that mutations in 12 additional genes ity to caspofungin, a glucan synthase ...These genes are such an analysis should give insights ...
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Defining the ABC of gene essentiality in streptococci
... The increased accessibility of next-generation sequen- cing (NGS) technologies has facilitated the development of a variety of transposon-genome junction sequencing techniques, which combine dense mutant libraries and ...
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Cytomegalovirus UL91 Is Essential for Transcription of Viral True Late (γ2) Genes
... these essential genes control transcription of late genes UL99 (pp28) and UL75 (gH) and activate the true-late ele- ment in the UL44 promoter ...true-late genes UL32 (pp150), UL73 (gN), UL75 ...
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Large-Scale Functional Genomic Analysis of Sporulation and Meiosis in Saccharomyces cerevisiae
... the genes required for meiosis and sporulation among 4323 nonessential Saccharomyces cerevisiae annotated open reading frames ...sporulation-essential genes were identified, including 78 novel ORFs ...
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Effects of nullisomic chromosome deficiencies on conjugation events in Tetrahymena thermophila: insufficiency of the parental macronucleus to direct postzygotic development.
... These results suggest that failure of Nulli conjugants to complete events of conjugation and produce viable progeny is the result of deficiencies for essential genes that[r] ...
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