estrogen deficiency
Osteoarthritis associated with estrogen deficiency
... gen deficiency alone can induce OA alterations in healthy cartilage or, by contrast, whether OP subchondral bone is the origin of the cartilage changes in these ...animals. Estrogen deficiency leads ...
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Estrogen deficiency induces bone loss by enhancing T cell production of TNF α
... from estrogen-replete ...of estrogen deficiency T cells stimulate osteoclastogenesis through a mechanism unre- lated to the presence of stromal cells and independent of regulation of OPG, RANKL, and ...
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Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation
... Generalized osteoporosis in postmenopausal rheumatoid arthritis (RA) is caused both by estrogen deficiency and by the inflammatory disease. The relative importance of each of these factors is unknown. The ...
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Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss
... Totally, 18 specific pathogen-free C57BL/6 J female mice (7 weeks of age) were randomly divided into three groups and six mice for per group (sham group, OVX group, and test group (3 mg/kg Chrysosplenetin injection). The ...
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The effects of Cordyceps sinensis phytoestrogen on estrogen deficiency induced osteoporosis in Ovariectomized rats
... These findings suggested that the effect of CSIF on osteoporosis is due to decrease CTX and IFN-γ level, as well as increase the OC level in plasma in OVX animals. The mineral dissolution of bone from the CSIF treated ...
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A crucial role for thiol antioxidants in estrogen deficiency bone loss
... of estrogen deficiency, but also predicts that bone loss seen in other situations in which ROS have been implicated, such as in aging and inflammation, might be caused by a prolonged augmentation of ROS ...
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Transgenic mice expressing soluble tumor necrosis factor receptor are protected against bone loss caused by estrogen deficiency
... back with the posterior legs maintained in external rotation with a tape. The hip, knee, and ankle articulations were in 90 8 flexion. Bone mineral content (BMC), bone mineral density (BMD) and scanned area were recorded ...
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Pyrroloquinoline Quinone Prevents Estrogen Deficiency-Induced Osteoporosis by Inhibiting Oxidative Stress and Osteocyte Senescence
... Accumulating studies have shown that oxidative stress increases with aging, which is related to the pathophysiology of postmenopausal osteoporosis. Pyrroloquinoline quinone (PQQ) is a natural anti-oxidant with ...
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Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow
... an estrogen deficiency stimulates accumulation of B lymphocyte ...with estrogen then co-cultured with bone marrow cells in the presence of estrogen, the stromal ...
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Estrogen deficiency and bone loss: an inflammatory tale
... how estrogen deficiency causes bone loss, the mecha- nisms involved have proven to be complex and ...Although estrogen is established to have direct effects on bone cells, recent animal studies have ...
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MicroRNA-23a Participates in Estrogen Deficiency Induced Gap Junction Remodeling of Rats by Targeting GJA1
... alternations in the post-menopausal women. On the other hand, in terms of lifespan, 18 months old rats are equivalent to human around 50 years old and that is the average menopausal onset age of women [37-38]. In the ...
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Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow Evidence for autonomy from factors released during bone resorption
... that estrogen loss increases the number of mesenchymal progenitors that are capable of committing to the osteoblast lineage in the murine bone mar- row, and that these changes are temporally linked with in- ...
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Original Article miR-193-3p ameliorates bone resorption in ovariectomized mice by blocking NFATc1 signaling
... trogen deficiency-induced metabolic bone dis- order, is one of the most prevalent forms of pri- mary osteoporosis and occurs in approximately 50% of postmenopausal women worldwide ...present, estrogen ...
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Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae
... in estrogen deficiency, we studied effects on cultured neonatal mouse calvariae of bone marrow supernatants (MSup) from sham-operated (SHAM), ovariectomized (OVX), or 17 beta-estradiol (OVX+E)-treated ...
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Review Article The Role of T Cells in Osteoporosis, an Update
... Abstract: Emerging evidence highlights the importance of the interplay between the bone and immune systems. That evidence bolsters a longstanding recognition that estrogen deficiency, infection, ...
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Efficacy of biorhythmic transdermal combined hormone treatment in relieving climacteric symptoms: a pilot study
... this estrogen deficiency, most notably vasomotor instability (hot flashes) and sleep ...of estrogen deficiency have lasting and cumulative consequences, such as accelerated loss of ...
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œstrogènes et contrôle de la prolifération germinale
... The role of so-called female sex steroids in males needs to be completely re-evaluated in the light of the clinical features of male estrogen deficiency, new me[r] ...
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Associations Factors Affecting on Osteoporosis in Postmenopausal Women in Saudi Arabian, Jeddah
... the estrogen deficiency is a major risk factor in early and the late phase of bone loss in women, since estrogens have a very favorable, antiresorptive and a discreet anabolic effect on bone tissue ...
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Serum Ferritin: Is It an Independent Predictor of Reduced Bone Mineral Density among Elderly Women?
... men. Estrogen deficiency is the main cause of postmenopausal osteoporosis as it is associated with increased bone turnover rate and remodeling imbalance of bone resorption exceeding bone formation ...to ...
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The combination of Artemisia princeps Pamp, Leonurus japonicas Houtt, and Gardenia jasminoides Ellis fruit attenuates the exacerbation of energy, lipid, and glucose by increasing hepatic PGC 1α expression in estrogen deficient rats
... pected, estrogen deficiency offsets the estrogen effects in these processes, which leads to metabolic disorders such as insulin resistance, obesity, dyslipidemia, high blood pressure and ...unclear. ...
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