Ex Vivo Perfusion Model
A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis
... the ex vivo lung perfusion (EVLP) model of infection using porcine lungs to investigate Klebsiella pneumoniae-triggered pneumonia as a model of respiratory ...EVLP model ...
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Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study
... equal perfusion flow, resulted in higher vascular pressures ...septal perfusion during this phase of the respiratory ...septal perfusion in this group. We hypothesize that inferior perfusion ...
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Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model
... Core biopsies were taken from each kidney (n = 10) in situ (baseline) and after 6 h of perfusion. Biopsies were stored in RNA later solution (Invitrogen RNA later ™ Soln.) for fixing. The tissue was lysed ...
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Ex vivo lung perfusion as a human platform for preclinical small molecule testing
... a model of topical endotoxin injury, with treatment groups given mesenchymal stem cells (MSC) or MSC condi- tioned media and other modulators ...experimental model to assess lung function in the setting of ...
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Effect of renal perfusion and structural heterogeneity on shear wave elastography of the kidney: an in vivo and ex vivo study
... in vivo, we further established an ex vivo model to explore the effect of renal perfusion on kidney ...artery perfusion pressure, in good agree- ment with the variation trends ...
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Incorporating ex vivo lung perfusion into the UK adult lung transplant service: an economic evaluation and decision analytic model
... as model assumptions and parameters created ...the model would be potentially ...[23]. Model parameters and distributions are listed in Table 2, and an incremental cost-effectiveness plane and a ...
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A porcine ex vivo model of pigmentary glaucoma
... a model similar to human eyes in size and ...porcine ex vivo model that recreates several features of pigmentary glaucoma, including intraocular hypertension, accumulation of pigment in the ...
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Characterization of micro-invasive trabecular bypass stents by ex vivo perfusion and computational flow modeling
... in ex vivo anterior segment models, they have not previously been evaluated in whole eye perfusion models nor characterized by computational fluid ...an ex vivo whole human eye ...
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The effect of prolonged of warm ischaemic injury on renal function in an experimental ex vivo normothermic perfusion system
... Parekh et al. analysed the effects of warm and cold ischae- mia in human kidneys in a study of 40 patients undergo- ing partial nephrectomy for renal tumours [13]. The renal pedicle was cross-clamped to achieve ...
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Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model
... In our model, MAPC cells were administered in the airways. This route of administration is based on the pathological findings of ischemia-reperfusion injury and acute respiratory distress syndrome, which share a ...
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New Avenues for Nanoparticle Related Therapies
... during ex vivo per- fusion and successfully knocked-down MHC class II when transplanted to immunodeficient mouse hosts ...Furthermore, ex vivo organ perfusion can be used as a ...
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Effect of lung flooding and high-intensity focused ultrasound on lung tumours: an experimental study in an ex vivo human cancer model and simulated in vivo tumours in pigs
... Compared to other human tissues, a flooded lung has an ideally suitable beam path, because water has a very low attenuation. In contrast to flooded lung tissue, tumour tissue converts acoustic energy into a therapeutic ...
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Krapp, Jan David (2002): Computergesteuertes Perfusionssystem zur normothermen ex-vivo Vorbehandlung von Dünndarmtransplantaten. Dissertation, LMU München: Medizinische Fakultät
... Ein weiteres Problem das anfänglich bestand, waren die physikalische Hämolyse und der Abfall Hämatokritwertes über die 120 Minuten Perfusion, durch hämodynamisch ungünstig geformte Bestandteile des Systems. ...
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Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
... It is worthwhile to notice that organotypic slice cul- tures have become a powerful tool to study physiological and pharmacological properties of tissues, since they re- produce the in vivo environment, ...
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Characterising the tumour morphological response to therapeutic intervention : an ex vivo model
... In cancer, morphological assessment of histological tissue samples is a fundamental part of both diagnosis and prognosis. Image analysis offers opportunities to support that assessment through quantitative metrics of ...
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Quantitative MRI correlates of hippocampal and neocortical pathology in intractable temporal lobe epilepsy
... to model the DW signal, such as apparent di ff usion coe ffi cient (ADC) or intravoxel incoherent motion ...(Charmed) model [81] represents the intra-cellular compartment as impermeable parallel cylinders ...
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Introduction of an ex vivo pig model for teaching percutaneous nephrolithotomy access techniques
... simulation model for learning and teaching percutaneous access was developed and ...The model used for this study was previously developed by ...This model uses pig tissue and common PCNL equipment ...
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Crypts-on-a-Chip : Developing an ex vivo Model of the Intestinal Crypts
... Proteases have a potential to compromise the integrity of cell surface molecules, which may impact the ability of ligands, peptides, or antibodies to bind to these surface receptors. CD24 and CD44 have been shown to bind ...
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Effect of the sensitization to Dermatophagoïdes pteronyssinus on the inflammatory response and bronchoconstrictive of brown Norway rats
... In order to clarify the implied mechanisms in the pathology of the asthma, several research on the asthmatic animal types have been realized. Inter species differences; the multiplicity of the immunization ways, the type ...
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Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model
... an ex vivo technique, DIC is particularly suitable for biological applications, as it reveals strains in inhomogeneous, aniso- tropic and non-linear materials, like bone, which has also a complex morphology ...
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