exchange factor
The Exchange Factor Cdc24 Is Required for Cell Fusion during Yeast Mating
... mammalian exchange factor conserved region 3 sequences are shown, with residues that are similar (boxed in grey) or identical (boxed in black) in 80% or more of the ...
13
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis
... Activation of Arhgef1/RhoA signaling by AT1 receptor stimu- lation is subsequent to the phosphorylation of the Tyr738 of Arh- gef1 by the tyrosine kinase Jak2 (16, 17). The Jak family of tyrosine kinases, classically ...
12
Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma
... Abstract: Guanine nucleotide exchange factor H1 (GEF-H1), which couples microtubule dynamics to RhoA activation, is a microtubule-regulated exchange factor. Studies have shown that GEF-H1 can ...
10
The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity
... Guanine exchange factor; GTP: Guanosine triphosphate; HHV8: Human herpes virus 8; HUVEC: Human umbilical vein endothelial cell; KS: Kaposi sarcoma; KSHV: Kaposi sarcoma herpes virus; LNA: Latent nuclear ...
7
New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia
... nucleotide exchange factor (RhoGEF), has been studied primarily in tissue culture, where it exhibits transforming ability, associates with and modulates the actin cytoskeleton, regulates neurite outgrowth, ...
11
Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22
... guanine-nucleotide exchange factor (GEF) of Rab1 [6,7] and whose N-terminal domain exhibits adenosine monophosphorylation (AMPylation) activity toward Rab1 ...
25
The GDP GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering
... Inhibitory neurotransmission relies on glycine and γ-aminobutyric acid (GABA) receptors being clustered at postsynaptic specializations opposite axon terminals releasing the corresponding neurotransmitters. Central to ...
44
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B
... ISRIB action converges on eIF2B, a protein complex with guanine nucleotide exchange (GEF) activity towards eIF2 (5) that is inhibited by phosphorylated eIF2 (6, 7). Addition of ISRIB accelerates eIF2B GEF activity ...
43
Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes
... This is the first study to show that LPS induces JNK- dependent hepatocyte apoptosis in vitro in the virtual absence of Kupffer and stellate cells, and that LPS’s effect is a[r] ...
11
Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
... initiation factor 2 (eIF2) is a G protein heterotrimer required for GTP-dependent delivery of initiator tRNA to the ...nucleotide exchange factor for eIF2, is a heteropen- tamer that, in yeast, is ...
10
Nck adapter proteins: functional versatility in T cells
... Upon TCR ligation, two p21-activated kinases (PAK1 and PAK2) are activated [66-69]. In non-lymphoid cells, PAK has been linked to various events associated with cytoskeletal dynamics [70]. PAK activation contributes to ...
13
A DOCK8 WIP WASp complex links T cell receptors to the actin cytoskeleton
... nucleotide exchange factor activity of DOCK8 is essential for the integrity of the subcortical actin cytoskeleton as well as for TCR-driven WASp activation, F-actin assembly, immune synapse formation, actin ...
16
Fama and French Three-Factor Model: Evidence from Istanbul Stock Exchange
... risk factor, RM-Rf, size risk factor (SMB) and BE/ME risk factor (HML) were used as the explanatory ...risk factor is found to be effective on each excess portfolio ...risk factor (SMB) ...
12
Monetary Fundamental-Based Exchange Rate Model in Iran: Applying a MS-TVTP Approach
... the exchange rate was that international flows of resources resulting from the imbalance of payments could be through their effects on the national money supply and price level, and therefore, the effect on the ...
22
Factors Shaping Agri-food Product Trade in Poland
... Poland has a positive rate of economic growth, but it has weakened in recent years. In 2009, GDP in Poland was 8,100 Euro/person and was lower than the EU average (23,600 Euro/person). For comparison, the GDP calculated ...
8
Real exchange rate and manufacturing growth in Latin America
... their exchange rates ...overvalued exchange rate, causing severe balance of payments difficulties, which, after a period of speculation against the currency, usually led to ...
17
The oil cycle, the Federal Reserve, and the monetary and exchange rate policies of Qatar
... Supporters of the Arab oil-exporting countries’ decades-long fixed exchange rate regime ar- gue that since, oil is traded in United States (US) dollars, pegging to the dollar is optimal. However, the weakening ...
36
Does Humble Leadership Behavior Promote Employees’ Voice Behavior?—A Dual Mediating Model
... We used AMOS19.0 to conduct a confirmatory factor analysis (CFA) of the variables. The hypothesized model fit the data reasonably (Table 1). CFA results showed that the four-factor model (i.e., humble ...
10
The Choice of Heat-Exchange Devices with Tubes Having Ring Turbulizers on Base Exergy Analysis
... [4] Zakirov S.G., Karimov K.F., Muminov A., Azizov D.X., Karabaev A.S., 2004, Report of Scientific Research Work ―Exergy Method of Thermodynamic Analysis of Heat Exchange Processes in Refrigerating Machines and ...
8