Exons and Introns
Characterizing exons and introns by regularity of nucleotide strings
... in introns and exons captured by the proposed ...in exons and introns would be inadequate if the accuracy of classifi- cation was questioned, since its discriminatory power is ...
17
Protecting exons from deleterious R-loops: a potential advantage of having introns
... I read this MS with interest and think that it deserves pub- lication. However, I am disappointed about the absence of any quantitative estimations of the effect of hybridiza- tion of transcripts with their DNA matrixes. ...
9
Synergistic assembly of human pre-spliceosomes across introns and exons
... internal exons can occur with exceptionally low frequency (~1 in 10 5 splicing events) (Fox-Walsh and Hertel, ...internal exons in multi-intron RNAs, enabling the human splicing machinery to avoid ...
19
Spliceosomal introns in Trichomonas vaginalis revisited
... were downloaded from the Sequence Read Archive at the National Center for Biotechnology Information (https://www.ncbi.nlm.nih.gov/sra). These datasets contain expressed sequences of T. vaginalis strains G3 and B7RC2, ...
9
U12-type Spliceosomal Introns of Insecta
... U12-type introns . The first U12-type intron, which lies between exons two and three, is absent in all the three mosquitoes and Pediculus but is conserved in the rest of the insects; whereas, the second ...
9
Selection on Position of Nonsense Codons in Introns
... for exons in protein coding genes, where tests based on silent and replacement site substitu- tions can be ...In introns, length, phase, and frequency of occur- rence have been studied as a product of the ...
19
Emergence and loss of spliceosomal twin introns
... Figures 4 and 5 show the clades of species that include the stwintron in more detail, to highlight instances of stwintron loss in Eurotiomycetes and Leotiomycetes, respectively (fungi that lost the lipS stwintron are ...
15
Introns and Splicing Elements of Five Diverse Fungi
... the introns, the distribution of polypyrimidine tracts within the introns, and homologs of se- lected proteins that have been associated with ...fungal introns are typically short and exons ...
13
PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons
... conserved exons are governed by splicing factors that can act as enhancers or repressors, depending on ...within introns—a consequence of mutations that accumulate over evolutionary ...cryptic exons, ...
11
Mobile Introns Shape the Genetic Diversity of Their Host Genes
... Self-splicing introns populate several highly conserved protein-coding genes in fungal and plant ...these introns have retained their ability to spread to intron-free target sites, often assisted by ...
9
Estimation of genetic distances from human and mouse introns
... in introns would allow us to test the prediction that, if a local rate variation exists and expands over large tracts of the genome, it would affect all parts of a gene, and therefore the evolutionary rates ...
7
Identification of motifs that function in the splicing of non canonical introns
... of introns and exons that act to recruit the spliceosome and associated splicing ...human introns that lack a canonical PY ...of introns that acts as a binding site for U2AF65, a key factor in ...
17
Tissue-specific classification of alternatively spliced human exons
... In general, the ACE skipped exons and non-ACE skipped exons are more divisible by 3, more modular, have less NMD, have longer introns, have shorter exons, have weaker spli[r] ...
57
Subdivision of Large Introns in Drosophila by Recursive Splicing at Nonexonic Elements
... long introns, but special mechanisms for their expression have not been ...large introns by recursive splicing at nonexonic elements and alternative ...of introns ⬎20 kb, but they are found only at ...
14
Identification of novel exons and transcribed regions by chimpanzee transcriptome sequencing
... annotated exons, mRNAs or ...new exons or 3' ...novel exons and UTRs, novel transcribed regions may also stem from different types of noncoding ...and introns from unspliced mRNAs are ...
16
Contrasting chromatin organization of CpG islands and exons in the human genome
... on exons compared to introns and whether it was associated with spliced exons rather than skipped exons, as H3K36me3 and nucleosomes were shown to ...
8
Detecting differential usage of exons from RNA-Seq data
... 2 Description of the method 2.1 Preparation: Flattening gene models and counting reads The initial step of an analysis is the alignment of the sequencing reads against the target genome. Here it is important to use a ...
19
Molecular characterization of a new member of the lariat capping twin-ribozyme introns
... This exoG becomes covalently bound at the 5′ end of the intron RNA, and subsequently, in a second reaction, the free 3′OH group of the 5′ exon attacks the phosphodiester bond at the 3′SS. This process results in the ...
13
Synergistic assembly of human pre-spliceosomes across introns and exons
... observed RNA molecules that exhibited subcomplex binding during the experiment is indicated. 716[r] ...
53