experimental asthma
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis
... conditions. Asthma models were induced by intraperitoneal injection with 100 µg OVA (grade V, Sigma-Aldrich, ...antigen-associated asthma was induced by challenging mice intranasally three times a week for ...
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Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental asthma
... The most characteristic protein regulations associated with neutrophilic experimental asthma included increased levels of acute phase reactants. The adaptive immune re- sponse is traditionally expected to ...
12
Animal models of chronic experimental asthma — strategies for the identification of new therapeutic targets
... of experimental asthma proved to be a valuable tool for the investigation of mechanisms that underlie acute allergic airway inflammation and development of airway hyperresponsiveness, two of the hallmarks ...
5
Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells
... To investigate the effects of the S1P/S1PR2 axis on bronchial asthma, we employed an experimental asthma mouse model and evaluated the therapeutic effects of JTE013. As expected, OVA-treated mice ...
8
Inhibition of experimental asthma by indoleamine 2,3 dioxygenase
... Epidemiological evidence points to the inverse relationship between microbial exposure and the prevalence of allergic asthma and autoimmune diseases in Westernized countries. The molecular basis for this obser- ...
11
Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma
... demonstrated that integrin α v β 6 -deficient mice are protected from airway hyperresponsiveness, due in part to increased expression of the murine ortholog of human chymase. Here, we determined that chymase protects ...
11
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function
... Airway DCs play a crucial role in the pathogenesis of allergic asthma, and interfering with their function could constitute a novel form of therapy. The sphingosine 1–phosphate receptor agonist FTY720 is an oral ...
11
Pentraxin 3 promotes airway inflammation in experimental asthma
... established. Immunization of mice with OVA/LPS has been reported to cause neutrophilic airway inflamma- tion, in contrast to the eosinophilic airway inflammation provoked by OVA/Alum [20]. We confirmed that immunization ...
10
Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice
... induces experimental asthma, but in a fashion independent of active ...of asthma we present, allergen-derived proteases play an important role in mediating allergic ...
12
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis
... Even though CAT2 is induced highly in asthma, it is not required for experimental asthma-induced inflammation. This observation is consistent with our recent finding that arginase is not required for ...
9
Study of pattern of drug treatment in patients with exacerbations of bronchial asthma in an emergency ward of a teaching hospital: A prospective, cross sectional study
... national asthma education and prevention program 2007 has published useful algorithms on the management of acute exacerbations of asthma depending on ...bronchial asthma at the emergency department ...
7
A review of adult asthma and the effectiveness of education programs in reducing symptoms
... The asthma care program must be a comprehensive treatment plan that integrates a dynamic education program about the pathophysiology of asthma, a comprehensive assess- ment of environmental triggers, and a ...
8
BRONCHIAL ASTHMA: AN UNMET DISEASE
... Epidemiology: Asthma is a common medical condition that affects 300 million people worldwide and 25 million people in United States with that number expected to ...that asthma usually affects 5-16% of the ...
8
Asthma Education: How much does it Improve Knowledge of Childhood Asthma Amongst Medical Students and Paramedics
... Asthma Education How much does it Improve Knowledge of Childhood Asthma Amongst Medical Students and Paramedics ORIGINAL ARTICLE Asthma Education How Much Does it Improve Knowledge of Childhood Asthma[.] ...
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Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy
... ACQ: Asthma Control Questionnaire; ANOVA: Analysis of Variance; Asthma BRIDGE: Asthma BioRepository for Integrative Genomic Exploration; CACS: Chronic Asthma Control Score; C-ACT: Childhood ...
8
Three Courses of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinic Efficacy Observation Trail
... chronic asthma were recruited from 2010 to 2015: 323 in 2010, 391 in 2011, 283 in 2012, 206 in 2013, 164 in 2014, and 149 in 2015, among them 910 person-time completed Tianjiu Therapy (242 in 2010, 169 in 2011, ...
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Physician perspectives on the burden and management of asthma in six countries: The Global Asthma Physician Survey (GAPS)
... comparing asthma management in different types of physicians in Italy found that use of the ACT was consid- erably higher in pneumologists and allergologists than in general practitioners ...
11
The all age asthma cohort (ALLIANCE) - from early beginnings to chronic disease: a longitudinal cohort study
... of asthma in children and in adults are rather uniform with wheezing, shortness of breath and cough, population-based clinical and genetic studies suggest that asthma is not one disease but many ...
13
Clinical and epidemiological study of bronchial asthma in children & assessment of severity of asthma and its correlation with serum IgE levels
... BRONCHIAL ASTHMA IN CHILDREN & ASSESSMENT OF SEVERITY OF ASTHMA AND ITS CORRELATION WITH SERUM IgE LEVELS” prepared by me at Government Mohan Kumaramangalam Medical College and Hospital,Salem-636030 ...
111
National and regional asthma programmes in Europe
... There is a bias with this review. The search was restricted to published data and many national programmes were probably not found. There is also a number of limitations when interpreting the results of the published ...
10