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Expression of key protease-regulated receptor genes

Integrated network analysis to explore the key genes regulated by parathyroid hormone receptor 1 in osteosarcoma

Integrated network analysis to explore the key genes regulated by parathyroid hormone receptor 1 in osteosarcoma

... of Genes and Genomes; MF: Molecular function; MMP2 : Matrix metalloproteinase 2; NF- κ B: Nuclear factor kappa B; NR4A2 : Nuclear receptor subfamily 4 group A member 2; OS: Osteosarcoma; PGC-1α : PPAR γ ...

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Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells

Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells

... of protease-activated receptor (PAR) 1 and 2 amongst the surface proteins expressed in ...negatively regulated by proteases able to stimulate PAR1 ...

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Circadian and Light Regulated Expression of CBFs and their Upstream Signalling Genes in Barley

Circadian and Light Regulated Expression of CBFs and their Upstream Signalling Genes in Barley

... high expression levels in response to cold; moreover, they play a key regulatory role in cold acclimation ...CBF expression. Earlier, studies established that the expression patterns of some ...

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Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors

Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors

... a key role in the formation of two important classes of cranial motoneurons, the bm and the closely related visceromotor ...whose expression is dependent on Phox2b in fbm precursors ...Phox2b- ...

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The Ethyl Acetate Fraction of Torbangun (Coleus amboinicus L.) Leaves Increasing Milk Production With Up-Regulated Genes Expression of Prolactin Receptor

The Ethyl Acetate Fraction of Torbangun (Coleus amboinicus L.) Leaves Increasing Milk Production With Up-Regulated Genes Expression of Prolactin Receptor

... Figure 2. The Expression of the estradiol receptor gene (ERα) of the mammary gland in lactating rats. These are real-time PCR results and fold change is with respect to the housekeeping gene. KO: control ...

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Expression of ADAMTS 8, a secreted protease with anti angiogenic properties, is down regulated in brain tumours

Expression of ADAMTS 8, a secreted protease with anti angiogenic properties, is down regulated in brain tumours

... are key events in tumour progression, and factors regulating stromal – epithelial interactions and matrix composition are potential targets for the development of novel anti-invasive/antiangiogenic ...the ...

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Identification of Pax2 regulated genes by expression profiling of the mid hindbrain organizer region

Identification of Pax2 regulated genes by expression profiling of the mid hindbrain organizer region

... ectopic expression experiments in chick embryos to further study the role of Brn1 and Brn2 in mid- hindbrain ...Ectopic expression of the transcriptional repressor EnR-Brn1 in combination with Otx2 strongly ...

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Molecular Evolution of Key Receptor Genes in Primates and Non-Human Primates

Molecular Evolution of Key Receptor Genes in Primates and Non-Human Primates

... gene expression, gene loss, gene duplication, and natural selection have received the most attention as the molecular mechanisms responsible for the differences in protein activity in these species [4, ...human ...

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Dihydropyridine receptor gene expression is regulated by inhibitors of myogenesis and is relatively insensitive to denervation

Dihydropyridine receptor gene expression is regulated by inhibitors of myogenesis and is relatively insensitive to denervation

... influence expression of the dihydropyridine-sensitive "slow" Ca2+ channel, we analyzed dihydropyridine receptor (DHPR) mRNA abundance in mouse skeletal ...gene expression was reversibly suppressed by ...

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Modulation of protease-activated receptor expression by Porphyromonas gingivalis in human gingival epithelial cells

Modulation of protease-activated receptor expression by Porphyromonas gingivalis in human gingival epithelial cells

... gingivalis proteases was investigated by quantitative real-time reverse transcription polymerase chain reaction (QRT-PCR) and flow cytometry. Results: PAR-1, PAR-2, and PAR-3 were expressed in GECs. PAR-4 was not found ...

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Abnormal expression of A20 and its regulated genes in peripheral blood from patients with lymphomas

Abnormal expression of A20 and its regulated genes in peripheral blood from patients with lymphomas

... cell receptor (TCR)-CD3 signaling ...abnormal expression of MALT1, A20, and NF-κB genes, which may be related to T cell im- munodeficiency, in T cells from patients with acute mye- loid leukemia ...

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Analysis of variation in NF κB genes and expression levels of NF κB regulated molecules

Analysis of variation in NF κB genes and expression levels of NF κB regulated molecules

... NF-κB genes and expression levels of 15 ...IRF1 expression phenotypes, and between REL and CD40 expression ...(TNF) receptor fam- ily; signals through FAS are able to induce ...

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Reference Genes for RT qPCR Analysis of Environmentally and Developmentally  Regulated Gene Expression in Alfalfa

Reference Genes for RT qPCR Analysis of Environmentally and Developmentally Regulated Gene Expression in Alfalfa

... reference genes identified a set of candidates with high potential as reference for normalization in RT-qPCR analysis of gene expression in ...alfalfa. Genes encoding ubiquitin protein ligase 2a ...

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Protease and Protease Activated Receptor 2 Signaling in the Pathogenesis of Atopic Dermatitis

Protease and Protease Activated Receptor 2 Signaling in the Pathogenesis of Atopic Dermatitis

... residual expression of ...a key regulator of KLK5 and KLK7 activity and that defective SC adhesion by epidermal protease hyperactivity is the primary pathogenic event in ...epidermal protease, ...

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Chemokine receptor CCR6 expression is regulated by miR 518a 5p in colorectal cancer cells

Chemokine receptor CCR6 expression is regulated by miR 518a 5p in colorectal cancer cells

... protein-coding genes could serve as miRNA ...aberrant expression of miRNAs in different cancer entities, it is yet unknown if this directly influences the carcinogenic process ...

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Human β-defensin 2 and protease activated receptor-2 expression in patients with chronic periodontitis

Human β-defensin 2 and protease activated receptor-2 expression in patients with chronic periodontitis

... b-defensins expression in the oral cavity can be orchestrated by receptors present in the cell membrane that recognize certain molecular patterns associ- ated to periodontal pathogens, including Aggregatibacter ...

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Genome-wide Expression Analysis of Mouse Liver Reveals CLOCK-regulated Circadian Output Genes*

Genome-wide Expression Analysis of Mouse Liver Reveals CLOCK-regulated Circadian Output Genes*

... mRNA expression levels of fatty acid synthetase and another two lipogenic enzymes, Lce and acyl-CoA synthase 4, were decreased in the liver of Clock mutant ...therefore key and rate-limiting, so it plays an ...

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Expression of Zebra Fish Aromatase cyp19a and cyp19b Genes in Response to the Ligands of Estrogen Receptor and Aryl Hydrocarbon Receptor

Expression of Zebra Fish Aromatase cyp19a and cyp19b Genes in Response to the Ligands of Estrogen Receptor and Aryl Hydrocarbon Receptor

... estrogen receptor (ER) or aryl hydrocarbon receptor ...the expression of zebra fish cyp19a (zfcyp19a) and cyp19b (zfcyp19b) genes, encoding aromatase P450, an important steroido- genic ...

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Spatial organization of genes as a component of regulated expression

Spatial organization of genes as a component of regulated expression

... INO1 genes, and retention of these genes in the cache of the periphery allows for faster gene activation than if those genes needed to be accessed from their original location, the ...regulate ...

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Steady-state expression of self-regulated genes

Steady-state expression of self-regulated genes

... noisy expression of the regulatory proteins that bind the promoter under study Blake and Collins, 2005, Blake et ...in expression in response to varying doses of the inducer ...

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