extracellular matrix protein
Extracellular matrix protein 1 is correlated to carcinogenesis and lymphatic metastasis of human gastric cancer
... Extracellular matrix protein 1 (ECM1) is a soluble pro- tein, which was first identified in 1994 [9]. Mutations in this gene were reported to be associated with lipoid pro- teinosis disorder (known ...
8
<p>Extracellular matrix protein 1 (ECM1) is associated with carcinogenesis potential of human bladder cancer</p>
... ecM1 protein in three representative ...ecM1 protein in cell ...ecM1, extracellular matrix protein 1; Bca, bladder cancer; qrT-Pcr, quantitative real-time Pcr; Tcga, The cancer genome ...
10
Investigating the role of the extracellular matrix protein, Spondin 1, in ovarian folliculogenesis
... the protein from the ECM as the fifth and sixth TSRs bind the ECM but TSRs 1-4 do not ...the protein is responsible for commissural axon guidance [137], while the reeler/spondin half is responsible for ...
188
Recombinant extracellular matrix protein fragments support human embryonic stem cell chondrogenesis
... noncommercial protein fragments were expressed in mammalian 293-EBNA cells and modified with either N or C terminal ...and protein concentrations were calculated using BCA Protein Assay (Pierce) ...
11
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del 1
... (P < 0.01), whether we applied purified recombinant Del-1 protein (Figure 5, a and b) or Del-1–expressing adenovirus (Figure 5, c and d) to CAMs. We hypothe- sized that if αvβ5 is required to induce αvβ3 ...
13
AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer
... To examine components downstream of PI3K/ AKT pathway, we focused on matrix metalloproteinases (MMPs) because they have been found to be major contributors to tumor cell invasion and metastasis [38-40]. Expression ...
15
Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein
... In conclusion, this study is the first demonstration that the latent TGF-[3 binding protein is a structural extracellular matrix protein involved in the formation of large fibrillar stru[r] ...
11
Alterations of perineuronal nets in the dorsolateral prefrontal cortex of neuropsychiatric patients
... an extracellular matrix protein, reported a downregulation in psychotic bipolar and schizophrenic patients when compared to control individuals and bipolar patients without psychosis (Guidotti et ...
9
Cytotoxic mAb from rheumatic carditis recognizes heart valves and laminin
... Anti-streptococcal antibodies cross-reactive with N-acetyl-β D -glucosamine (GlcNAc) and myosin are present in the sera of patients with rheumatic fever (RF). However, their role in tissue injury is not clear. In this ...
9
The DNA repair protein AlkB, EGL 9, and leprecan define new families of 2 oxoglutarate and iron dependent dioxygenases
... DNA-repair protein AlkB, the extracellular matrix protein leprecan and the disease-resistance-related protein EGL-9 define new families of the 2OG-Fe(II) dioxygenase super- ...EGL-9 ...
8
Design of Tissue-specific Cellular Microenvironments for Adipose-derived Stromal Cell Culture and Delivery
... the protein level, intracellular GPDH enzyme activity was measured using a GPDH Enzyme Activity Measurement Kit (Kamiya Biomedical Corporation, ...cytosolic protein content for each sample determined using ...
210
Identification of Extracellular DNA Binding Proteins in the Biofilm Matrix
... copper-binding protein CopL (47), from the SW analysis screen (Table 1), and two lipoproteins chosen at random, open reading frame (ORF) 0100, which belongs to the same protein family as 0419 identified in ...
30
EFFECTS OF BONE MORPHOGENETIC PROTEIN-2 AND PARATHYROID HORMONE-RELATED PEPTIDE ON COLLAGEN XI DURING SKELETAL DEVELOPMENT
... determine protein concentration using a BCA assay (Bio Rad; Hercules, ...of protein samples were combined with NuPA GE LDS sample buffer and β-mercaptoethanol (Life Technologies; Carlsbad, CA) and incubated ...
94
Recent Advances in Tissue Engineering and Regenerative Medicine
... of extracellular matrix that retains the hierarchical branching structures of airways and vasculature, seeded endothelial cells and transplanted these cells into ...acellular matrix is a feasible ...
7
Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage
... inhibitor p27 [54] and pro-apoptotic activities through in- hibition of MYB [55,56] or induction of p53 transcription [57]. MYCN together with MYB were shown to be in- volved in a reciprocal regulatory loop promoting ...
17
Extracellular Leucine-Rich Repeat Protein Let-4 is Required to Organize the Extracellular Matrix and Maintain Junctions in C. Elegans Epithelia
... I have identified a system with a correlation between apical ECM components and junctional defects, adding to the growing field of apical ECM studies. This is different from the previously described connections related ...
231
ESWT Enhances Expression of Pdia-3 which is a Key Factor of 1α,25-Dihydroxyvitamin D3 Rapid Membrane Signaling Pathway in Treatment of Early Osteoarthritis Knee
... Osteoarthritis had been considered to be primarily cartilage disorder characterized by cartilage degradation. Intensive inflammatory cytokines such as interleukin, tumor necrosis factor and proteases secreted from joint ...
21
Current achievements and future perspectives in whole-organ bioengineering
... Triton X-100. Chemical acid agents (that is, acetic acid or per-acetic acid) can solubilize the cytoplasmatic compo- nents removing the nucleic acids but, at the same time, they subtract the collagen from the ...
12
CIP2A mediates fibronectin-induced bladder cancer cell proliferation by stabilizing β-catenin
... β-catenin protein, though the exact mechanism was not yet ...phosphorylation. Protein phosphat- ase 2A (PP2A), whose catalytic phosphatase activity can be inhibited by CIP2A, has been reported to repress ...
12
Renovation of the egg extracellular matrix at fertilization
... extracellar matrix extend well into embryogenesis and adult ...a protein retains, the more freedom a structurally unrelated domain in that same protein would have to diverge without losing affinity ...
7